• Thumbnail for GAB2
    GRB2-associated-binding protein 2 also known as GAB2 is a protein that in humans is encoded by the GAB2 gene. GAB2 is a docking protein with a conserved, folded...
    26 KB (3,199 words) - 16:38, 17 July 2025
  • Thumbnail for Mast cell
    The tyrosine kinase FYN phosphorylates Grb2-associated-binding protein 2 (Gab2), which binds to phosphoinositide 3-kinase, which activates PKC. PKC leads...
    55 KB (6,212 words) - 18:37, 10 July 2025
  • Thumbnail for Yersinia pestis
    YopH also binds the p85 subunit of phosphoinositide 3-kinase, the Gab1, the Gab2 adapter proteins, and the Vav guanine nucleotide exchange factor.[citation...
    60 KB (6,764 words) - 18:28, 15 July 2025
  • Thumbnail for Signal transducing adaptor protein
    B-lineage Lymphoma FRS2 – Fibroblast growth factor receptor substrate 2 GAB2 – GRB2-associated binding protein 2 GRAP – GRB2-related adaptor protein GRAP2...
    6 KB (697 words) - 04:45, 15 July 2025
  • 𒆍 U+1218D KA2 222 133 π’†Ž U+1218E KA2 crossing KA2 𒆏 U+1218F KAB 148 88 GAB2 𒆐 U+12190 KAD2 108 63a 𒆑 U+12191 KAD3 109 63c π’†’ U+12192 KAD4 568 354b...
    117 KB (887 words) - 02:16, 23 January 2025
  • Thumbnail for PTPN11
    CD117, CD31, CEACAM1, Epidermal growth factor receptor, Erk FRS2, GAB1, GAB2, GAB3, Glycoprotein 130, Grb2, Growth hormone receptor, HoxA10, Insulin receptor...
    44 KB (4,906 words) - 19:14, 24 July 2025
  • Thumbnail for AKT1
    has been shown to interact with: AKTIP, BRAF, BRCA1, C-Raf, CDKN1B, CHUK GAB2, HSP90AA1, ILK, KRT10, MAP2K4, MAP3K11, MAP3K8, MAPK14, MAPKAPK2, MARK2,...
    24 KB (2,818 words) - 05:02, 19 July 2025
  • Thumbnail for GRB2
    growth factor receptor, Erythropoietin receptor, FRS2, Fas ligand, GAB1, GAB2, Glycoprotein 130, Granulocyte colony-stimulating factor receptor, HER2/neu...
    82 KB (9,409 words) - 01:43, 19 July 2025
  • HGNC:4057 P11413 5951 GAA HGNC:4065 P10253 5952 GAB1 HGNC:4066 Q13480 5953 GAB2 HGNC:14458 Q9UQC2 5954 GAB3 HGNC:17515 Q8WWW8 5955 GAB4 HGNC:18325 Q2WGN9...
    277 KB (17 words) - 09:51, 23 June 2025
  • Thumbnail for Colony stimulating factor 1 receptor
    actin bundling Iba1 Ionized Ca2C-binding adaptor protein 1; actin bundling Gab2 Grb2-associated binder-2; Adaptor Gab3 Grb2-associated binder-3; adaptor...
    44 KB (4,600 words) - 06:55, 15 July 2025
  • Thumbnail for RICS (gene)
    RICS (gene) has been shown to interact with: BCAR1, CDC42, CRK, CRKL, FYN, GAB2, GRIN2B, NCK1, RAC1, RHOA, SHC3, Src, and TrkA. The Mir-132 microRNA has...
    14 KB (1,849 words) - 18:11, 17 July 2025
  • Lufei; Li, Yi; Yang, Ping (February 2021). "Genetic association of BIN1 and GAB2 in Alzheimer's disease: A meta-analysis and systematic review". Geriatrics...
    89 KB (9,222 words) - 01:35, 29 July 2025
  • Thumbnail for PIK3R1
    CBLB, CD117, CD28, CD7, CENTG1, CBL, EPHA2, EPOR, ERBB3, EZR, FCGR2A, GAB1, GAB2, Grb2, HRAS, IRS1 IRS2, IL1R1, JAK2, KHDRBS1, LTK, LAT, LCP2, PIK3CD, PTK2...
    28 KB (3,136 words) - 06:56, 19 July 2025
  • Thumbnail for PLCG2
    and SH3. PLCG2 has been shown to interact with: Bruton's tyrosine kinase, GAB2, LYN, PTPN11, and SHC1 GRCh38: Ensembl release 89: ENSG00000197943 – Ensembl...
    12 KB (1,405 words) - 17:55, 17 July 2025
  • Thumbnail for RAC1
    GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". The Journal of Biological Chemistry. 278 (36): 34641–34653. doi:10.1074/jbc...
    29 KB (3,117 words) - 05:34, 29 September 2024
  • Thumbnail for CRKL
    Abl gene, BCAR1, BCR gene, CBLB, CD117, CD34, Cbl gene, Dock2, EPOR, GAB1, GAB2, INPP5D, MAP4K1, MAP4K5, NEDD9, PIK3R2, Paxillin RAPGEF1, RICS, STAT5A, Syk...
    27 KB (3,165 words) - 16:12, 17 July 2025
  • Thumbnail for NCK1
    GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". J. Biol. Chem. 278 (36): 34641–53. doi:10.1074/jbc.M304594200. PMIDΒ 12819203...
    28 KB (3,458 words) - 16:34, 19 July 2025
  • Thumbnail for Pleckstrin homology domain
    FAM109A, FAM109B, FARP1, FARP2, FGD1, FGD2, FGD3, FGD4, FGD5, FGD6, GAB1, GAB2, GAB3, GAB4, GRB10, GRB14, GRB7, IRS1, IRS2, IRS4, ITK, ITSN1, ITSN2, KALRN...
    16 KB (1,624 words) - 09:34, 30 June 2025
  • Thumbnail for CDC42
    GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". The Journal of Biological Chemistry. 278 (36): 34641–53. doi:10.1074/jbc...
    31 KB (3,700 words) - 16:24, 13 October 2024
  • Thumbnail for ARHGAP31
    GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". J. Biol. Chem. 278 (36): 34641–53. doi:10.1074/jbc.M304594200. PMIDΒ 12819203...
    6 KB (746 words) - 05:08, 19 July 2025
  • Thumbnail for GRAP
    GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". The Journal of Biological Chemistry. 278 (36): 34641–53. doi:10.1074/jbc...
    5 KB (621 words) - 17:27, 16 July 2025
  • Thumbnail for INPP5D
    (March 2000). "Shc associates with the IL-3 receptor beta subunit, SHIP and Gab2 following IL-3 stimulation. Contribution of Shc PTB and SH2 domains". Cellular...
    25 KB (3,055 words) - 06:09, 19 July 2025
  • Thumbnail for Adapter molecule crk
    GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2". J. Biol. Chem. 278 (36): 34641–53. doi:10.1074/jbc.M304594200. PMIDΒ 12819203...
    24 KB (2,943 words) - 16:14, 16 July 2025
  • ISBNΒ 0-8247-9728-0 Interleukin-3 (IL-3)-induced c-fos activation is modulated by Gab2-calcineurin interaction. Pyarajan S, Matejovic G, Pratt JC, Baksh S, Burakoff...
    9 KB (915 words) - 17:39, 6 March 2025