Nucleoside-diphosphate kinases (NDPKs, also NDP kinase, (poly)nucleotide kinases and nucleoside diphosphokinases) are enzymes that catalyze the exchange...
20 KB (2,538 words) - 00:00, 25 September 2024
disrupted nucleoside diphosphate kinase, adenylate kinase performed dual enzymatic functions. ADK complements nucleoside diphosphate kinase deficiency...
21 KB (2,459 words) - 00:32, 6 January 2024
Nucleoside diphosphate kinase A is an enzyme that in humans is encoded by the NME1 gene. It is thought to be a metastasis suppressor. This gene (NME1)...
13 KB (1,528 words) - 13:44, 4 January 2024
molecule, another kinase, thymidylate kinase, can act upon dTMP to create the diphosphate form, dTDP. Nucleoside diphosphate kinase catalyzes production...
34 KB (3,808 words) - 15:55, 11 April 2025
reactions catalyzed by the enzyme families of nucleoside diphosphate kinases (NDKs), which use other nucleoside triphosphates as a high-energy phosphate donor...
52 KB (5,657 words) - 03:17, 19 May 2025
kinase and further to thymidine triphosphate by the enzyme nucleoside diphosphate kinase. The triphosphate is included in a DNA molecule, a reaction...
103 KB (11,263 words) - 11:00, 28 February 2025
uridine diphosphate, which nucleoside diphosphate kinase can phosphorylate into uridine triphosphate. Thymidine phosphorylase or pyrimidine-nucleoside phosphorylase...
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nucleoside diphosphate Thus, the two substrates of this enzyme are ATP and nucleoside monophosphate, whereas its two products are ADP and nucleoside diphosphate...
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CTP via CTP synthetase. UTP can be biosynthesized from UDP by Nucleoside Diphosphate Kinase after using the phosphate group from ATP. UDP + ATP ⇌ UTP +...
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enzymology, a diphosphate-purine nucleoside kinase (EC 2.7.1.143) is an enzyme that catalyzes the chemical reaction diphosphate + a purine nucleoside ⇌ {\displaystyle...
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molecule of ATP, since GTP is readily converted to ATP with nucleoside-diphosphate kinase (NDK). During the elongation stage of translation, GTP is used...
8 KB (607 words) - 22:54, 16 December 2024
is catalyzed by nucleoside diphosphate kinase, which utilizes ATP as the phosphate donor. Similarly, nucleoside monophosphate kinase facilitates the phosphorylation...
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nucleotide kinase is any kinase taking a nucleotide reactant. It may mean: Nucleoside-phosphate kinase, EC 2.7.4.4 Nucleoside-diphosphate kinase, EC 2.7...
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(replacement) of nucleoside diphosphates for nucleoside triphosphates bound to other proteins. Many cellular proteins cleave (hydrolyze) nucleoside triphosphates...
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Guanosine diphosphate, abbreviated GDP, is a nucleoside diphosphate. It is an ester of pyrophosphoric acid with the nucleoside guanosine. GDP consists...
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formed by GDP-forming succinyl-CoA synthetase may be utilized by nucleoside-diphosphate kinase to form ATP (the catalyzed reaction is GTP + ADP → GDP + ATP)...
55 KB (6,095 words) - 06:15, 12 May 2025
} nucleoside diphosphate + ADP Thus, the two substrates of this enzyme are nucleoside triphosphate and AMP, whereas its two products are nucleoside diphosphate...
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step for NRTIs, including nucleoside diphosphate kinase (NDP kinase), phosphoglycerate kinase, pyruvate kinase and creatine kinase, resulting in formation...
33 KB (3,234 words) - 06:11, 2 November 2024
Nucleoside diphosphate kinase 3 is an enzyme that in humans is encoded by the NME3 gene. NME3 has been shown to interact with NME1 and NME2. Mutations...
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Nucleoside diphosphate kinase B is an enzyme that in humans is encoded by the NME2 gene. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed...
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Nucleotide (redirect from Nucleoside diphosphate)
called a nucleoside), and one phosphate group. With all three joined, a nucleotide is also termed a "nucleoside monophosphate", "nucleoside diphosphate" or...
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Mitochondrial DNA depletion syndrome (redirect from Nucleoside bypass therapy)
succinyl-CoA, but is also associated with the complex formed by nucleoside diphosphate kinase (NDPK) in the last step of the dNTP salvage pathway. The RRM2B...
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form), which can inhibit ribonucleotide reductase. Nucleoside-diphosphate kinase or nucleoside kinase A adds the third phosphoryl group to form dFdCTP (gemcitabine...
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resulting in the formation of ADP and the corresponding nucleoside diphosphate. These nucleoside diphosphates are required for cellular nucleic acid synthesis...
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In enzymology, a (deoxy)nucleoside-phosphate kinase (EC 2.7.4.13) is an enzyme that catalyzes the chemical reaction ATP + deoxynucleoside phosphate ⇌...
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selection and Darwinian evolution. Becker et al. showed how pyrimidine nucleosides can be synthesized from small molecules and ribose, driven solely by...
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Ca2+/calmodulin-dependent protein kinase Cell signaling Cyclin-dependent kinase G protein-coupled receptor Nucleoside-diphosphate kinase Phosphatase Phosphatidylinositol...
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to as polymerase inhibitors.[citation needed] RTIs come in four forms: Nucleoside analog reverse-transcriptase inhibitors (NARTIs or NRTIs) Nucleotide analog...
25 KB (2,897 words) - 23:33, 1 December 2024
nucleoside-diphosphate kinase EC 2.7.4.7: phosphomethylpyrimidine kinase EC 2.7.4.8: guanylate kinase EC 2.7.4.9: dTMP kinase EC 2.7.4.10: nucleoside-triphosphate—adenylate...
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respectively. They are first reduced by RNR and then phosphorylated by nucleoside diphosphate kinases to dATP and dGTP. Ribonucleotide reductase is controlled by...
22 KB (2,619 words) - 09:08, 30 January 2025