Pattern recognition receptors (PRRs) play a crucial role in the proper function of the innate immune system. PRRs are germline-encoded host sensors, which...
49 KB (5,846 words) - 12:19, 18 July 2025
in the host. They are recognized by toll-like receptors (TLRs) and other pattern recognition receptors (PRRs) in both plants and animals. This allows...
18 KB (2,145 words) - 12:14, 18 July 2025
RIG-I (category RIG-I-like receptors)
RIG-I (retinoic acid-inducible gene I) is a cytosolic pattern recognition receptor (PRR) that can mediate induction of a type-I interferon (IFN1) response...
24 KB (2,964 words) - 09:30, 13 July 2025
EF-Tu receptor, abbreviated as EFR, is a pattern-recognition receptor (PRR) that binds to the prokaryotic protein EF-Tu (elongation factor thermo unstable)...
12 KB (1,511 words) - 12:42, 27 December 2023
on interacting with TLR5 on human T cells. TLRs are a type of pattern recognition receptor (PRR) and recognize molecules that are broadly shared by pathogens...
61 KB (6,771 words) - 19:25, 22 May 2025
receptors (retinoic acid-inducible gene-I-like receptors, RLRs) are a type of intracellular pattern recognition receptor involved in the recognition of...
25 KB (3,011 words) - 17:07, 24 May 2024
promotes a noninfectious inflammatory response by binding to a pattern recognition receptor (PRR). Inflammation is a key aspect of the innate immune response;...
37 KB (3,643 words) - 04:04, 17 July 2025
via the phagocytic pathway. In this way, the mannose receptor acts as a pattern recognition receptor. The presence of a di-aromatic FENTLY (Phe-Glu-Asn-Thr-Leu-Tyr)...
32 KB (3,691 words) - 05:54, 2 June 2025
cells utilize specialized receptors known as Pattern Recognition Receptors(PRRs) to detect viral infection; these receptors are able to recognize pathogen-associated...
8 KB (1,059 words) - 14:12, 24 January 2024
through a common structural motif, RAGE is often referred to as a pattern recognition receptor. RAGE also has at least one other agonistic ligand: high mobility...
58 KB (6,883 words) - 02:35, 18 July 2025
MDA5 (category RIG-I-like receptors)
family, which also includes RIG-I and LGP2, and functions as a pattern recognition receptor capable of detecting viruses. It is generally believed that MDA5...
19 KB (2,222 words) - 17:53, 16 July 2025
being activated by pattern recognition receptors (PRRs) that recognize evolutionarily conserved pathogen-associated molecular patterns (PAMPs) as infectious...
11 KB (1,153 words) - 15:53, 1 September 2024
protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified. Discovered by Tillett and Francis in...
48 KB (5,497 words) - 17:00, 16 July 2025
mast cells. These cells present receptors contained on the surface or within the cell, named pattern recognition receptors (PRRs), which recognize molecules...
44 KB (4,847 words) - 17:37, 16 July 2025
Toll-like receptor 1 (TLR1) is a member of the toll-like receptor (TLR) family of pattern recognition receptors (PRRs) that form the cornerstone of the...
12 KB (1,372 words) - 07:28, 15 July 2025
immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor for a variety of β-1,3-linked and β-1,6-linked glucans from fungi...
15 KB (1,690 words) - 16:56, 16 July 2025
protein with an extracellular carbohydrate recognition domain. It functions as a pattern recognition receptor recognizing α-mannans and as such plays an...
8 KB (1,070 words) - 23:12, 2 January 2024
CD14 was the first described pattern recognition receptor. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection...
7 KB (849 words) - 07:02, 15 July 2025
gene. TLR4 belongs to the toll-like receptor family which is representative of the pattern recognition receptors (PRR), so named for their ability to...
75 KB (9,113 words) - 21:00, 18 July 2025
phylogenetically more highly developed. Pattern-recognition receptors (PRRs) come into play here. These are receptors that recognize the gross, primarily...
21 KB (2,370 words) - 18:49, 16 July 2025
the human brain Pattern recognition receptor, receptors of the innate immune system that identify pathogen-associated molecular patterns Pennsylvania Railroad...
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R gene (section Pattern recognition receptors (PRRs))
essential for pathogen defense are pattern recognition receptors (PRRs), wall associated kinase (WAKs), receptors with nucleotide-binding domain (NLRs)...
18 KB (2,099 words) - 18:35, 12 August 2024
by the TLR3 gene. TLR3 is a member of the toll-like receptor family of pattern recognition receptors of the innate immune system. TLR3 recognizes double-stranded...
9 KB (1,027 words) - 18:49, 16 July 2025
NOD2 (category NOD-like receptors)
and stimulates an immune reaction. NOD2 is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants...
13 KB (1,533 words) - 17:38, 17 July 2025
neuroscience, pattern recognition is a cognitive process that matches information from a stimulus with information retrieved from memory. Pattern recognition occurs...
35 KB (4,555 words) - 09:26, 14 July 2025
genomes. The CpG PAMP is recognized by the pattern recognition receptor (PRR) Toll-Like Receptor 9 (TLR9), which is constitutively expressed only in...
11 KB (1,393 words) - 18:39, 23 February 2024
immunoglobulin-like receptors Major histocompatibility complex (MHC) NOD-like receptors Pattern recognition receptor Toll-like receptors RIG-I like receptors Dynein...
3 KB (275 words) - 18:18, 23 June 2025
immunoglobulin E receptors (e.g., FcεRI), physical injury through pattern recognition receptors for damage-associated molecular patterns (DAMPs), microbial...
55 KB (6,212 words) - 18:37, 10 July 2025
of the toll-like receptor (TLR) family and detects single stranded RNA. The TLR family plays an important role in pathogen recognition and activation of...
13 KB (1,424 words) - 18:38, 17 July 2025
family, which belongs to the pattern recognition receptor (PRR) family. TLR6 acts in a heterodimer form with toll-like receptor 2 (TLR2). Its ligands include...
8 KB (1,073 words) - 07:34, 19 July 2025