Jun dimerization protein 2 (JUNDM2) is a protein that in humans is encoded by the JDP2 gene. The Jun dimerization protein is a member of the AP-1 family...
37 KB (4,166 words) - 19:15, 12 April 2025
Transcription factor Jun is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with protein c-Fos, forms the AP-1 early response...
46 KB (5,537 words) - 17:29, 19 February 2025
molecules, such as calcium or glutamate, protein phosphorylation state, protein complementation, receptor dimerization, and other processes provide highly...
66 KB (7,627 words) - 19:39, 1 June 2025
political party in Turkey Juicy Drop Pop, a brand of lollipops Jun dimerization protein, a member of the AP-1 family of transcription factors J.D. Power...
890 bytes (139 words) - 03:16, 22 May 2024
repeats. Cdc4 is a WD-40 repeat F-box protein. Like all members of this family, it contains a conserved dimerization motif called D domain. In yeast Cdc4...
16 KB (1,874 words) - 01:46, 3 December 2023
the cell. The dimerization and docking (D/D) domain of the dimer binds to the A-kinase binding (AKB) domain of A-kinase anchor protein (AKAP). The AKAPs...
27 KB (2,665 words) - 16:53, 12 May 2025
AP-1 transcription factor (redirect from Activation Protein 1)
zipper is responsible for dimerization of the Jun and Fos protein subunits. This structural motif twists two alpha helical protein domains into a “coiled...
42 KB (4,614 words) - 10:42, 5 February 2025
Extracellular signal-regulated kinases (ERKs) c-Jun N-terminal kinases (JNKs) p38 mitogen-activated protein kinases (p38s) Generally, ERKs are activated...
46 KB (5,510 words) - 21:54, 29 November 2024
Leucine zipper (category Protein structural motifs)
alpha helix of a second polypeptide, facilitating dimerization. Leucine zippers are a dimerization motif of the bZIP (Basic-region leucine zipper) class...
16 KB (2,049 words) - 20:45, 24 May 2025
Activating transcription factor 2 (category Moonlighting proteins)
eukaryotic transcription factors, Jun dimerization protein 2 and activation transcription factor 2, in Escherichia coli by Jun N-terminal kinase 1". Anal. Biochem...
19 KB (2,261 words) - 06:43, 5 December 2023
involved in dimerization and DNA binding, as are other transcription factors of the leucine zipper domain-containing family (c-Fos and c-jun). The bZIP...
15 KB (1,802 words) - 02:08, 26 May 2025
kDa protein, which forms heterodimer with c-jun (part of Jun family of transcription factors), resulting in the formation of AP-1 (Activator Protein-1)...
26 KB (3,991 words) - 05:29, 10 July 2024
Transcription factor JunD is a protein that in humans is encoded by the JUND gene. The protein encoded by this intronless gene is a member of the JUN family, and...
13 KB (1,561 words) - 16:46, 26 May 2025
FKBP (redirect from FK506 binding protein)
dimerize in the presence of FK1012, a derivative of the drug tacrolimus (FK506). This has made it a useful tool for chemically induced dimerization applications...
6 KB (656 words) - 18:45, 22 August 2023
ABC transporter (redirect from ABC Transporter Protein Family)
that is the case, the key point is that the NBD does not dimerize unless ATP and binding protein is bound to the transporter. Prokaryotic ABC exporters...
111 KB (14,448 words) - 00:51, 28 May 2025
gene) is an ovarian BH3 domain-containing proapoptotic Bcl-2 protein capable of dimerization with diverse antiapoptotic Bcl-2 members". Molecular Endocrinology...
19 KB (2,223 words) - 05:29, 3 January 2024
derived from immunoglobulin Fc domain, allow dimerization and solubilization. Can be used for purification on Protein-A Sepharose Designed Intrinsically Disordered...
24 KB (2,683 words) - 05:50, 23 May 2025
which phosphorylate a specific tyrosine residue within the STAT protein promoting dimerization via their SH2 domains. The phosphorylated dimer is then actively...
6 KB (514 words) - 10:42, 22 May 2025
Protein phosphorylation is a reversible post-translational modification of proteins in which an amino acid residue is phosphorylated by a protein kinase...
67 KB (7,955 words) - 05:53, 8 May 2025
et al. (June 2008). "Structural properties of AMP-activated protein kinase: dimerization, molecular shape, and changes upon ligand binding". The Journal...
65 KB (7,149 words) - 18:25, 23 May 2025
BZIP domain (redirect from BZIP protein)
together (dimerize) two DNA binding regions. The DNA binding region comprises a number of basic amino acids such as arginine and lysine. Proteins containing...
7 KB (663 words) - 00:42, 13 March 2024
P53 (redirect from Protein P53)
"Biogenesis of p53 involves cotranslational dimerization of monomers and posttranslational dimerization of dimers. Implications on the dominant negative...
131 KB (14,418 words) - 05:49, 1 June 2025
2010). "A crystal structure of the cyclic GMP-dependent protein kinase I{beta} dimerization/docking domain reveals molecular details of isoform-specific...
8 KB (825 words) - 21:37, 20 April 2023
chemically induced dimerization applications. FK1012 is a chemical inducer of dimerization (CID) which makes the protein capable of dimerization or oligomerization...
5 KB (333 words) - 21:35, 23 May 2025
FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family (e.g., c-Jun, JunD), thereby forming the transcription...
57 KB (7,191 words) - 12:09, 14 April 2025
The unfolded protein response (UPR) is a cellular stress response related to the endoplasmic reticulum (ER) stress. It has been found to be conserved...
31 KB (3,654 words) - 17:39, 10 May 2025
STAT5 (category Proteins)
STAT5-STATX, with other STAT proteins. The SH2 domains of the STAT5 proteins are once again used for this dimerization. STAT5 can also form homo-tetramers...
11 KB (1,215 words) - 11:33, 23 September 2023
Growth hormone-binding protein (GHBP) is a soluble carrier protein for growth hormone (GH). The full range of functions of GHBP remains to be determined...
23 KB (2,742 words) - 02:25, 27 May 2025
Nerve growth factor (category Proteins)
expression of pro-apoptotic proteins is increased when the activation of cell death-promoting transcription factors such as c-Jun are not suppressed by the...
27 KB (3,118 words) - 21:39, 29 May 2025
Melatonin receptor 1A (category G protein-coupled receptors)
E, Angers S, Fossier P, Bouvier M, Jockers R (Jun 2002). "Monitoring of ligand-independent dimerization and ligand-induced conformational changes of melatonin...
8 KB (1,006 words) - 08:50, 28 November 2024