• Polyadenylation is the addition of a poly(A) tail to an RNA transcript, typically a messenger RNA (mRNA). The poly(A) tail consists of multiple adenosine...
    57 KB (7,095 words) - 12:54, 22 February 2024
  • Thumbnail for Mature messenger RNA
    of a mature mRNA molecule occurs in 3 steps: Capping of the 5' end Polyadenylation of the 3' end RNA Splicing of the introns During capping, a 7-methylguanosine...
    6 KB (596 words) - 00:20, 15 February 2023
  • Thumbnail for SV40
    SV40 is an abbreviation for simian vacuolating virus 40 or simian virus 40, a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses...
    19 KB (2,241 words) - 16:21, 28 March 2024
  • Thumbnail for Three prime untranslated region
    Regulatory regions within the 3′-untranslated region can influence polyadenylation, translation efficiency, localization, and stability of the mRNA. The...
    20 KB (2,555 words) - 11:24, 22 February 2024
  • Cleavage and polyadenylation specificity factor (CPSF) is involved in the cleavage of the 3' signaling region from a newly synthesized pre-messenger RNA...
    15 KB (1,894 words) - 16:46, 28 November 2023
  • Thumbnail for Messenger RNA
    early stop codon, which, upon translation, produces a shorter protein. Polyadenylation is the covalent linkage of a polyadenylyl moiety to a messenger RNA...
    49 KB (5,922 words) - 00:21, 9 May 2024
  • Thumbnail for Post-transcriptional modification
    tail. The cleavage and adenylation reactions occur primarily if a polyadenylation signal sequence (5'- AAUAAA-3') is located near the 3' end of the pre-mRNA...
    11 KB (1,438 words) - 13:16, 13 April 2024
  • Thumbnail for CPEB
    CPEB, or cytoplasmic polyadenylation element binding protein, is a highly conserved RNA-binding protein that promotes the elongation of the polyadenine...
    19 KB (2,236 words) - 04:01, 27 May 2024
  • The cytoplasmic polyadenylation element (CPE) is a sequence element found in the 3' untranslated region of messenger RNA. While several sequence elements...
    9 KB (1,178 words) - 13:13, 22 February 2024
  • Thumbnail for U1A polyadenylation inhibition element (PIE)
    The U1A polyadenylation inhibition element (PIE) is an RNA element which is responsible for the regulation of the length of the polyA tail of the U1A...
    2 KB (175 words) - 17:50, 16 January 2022
  • Thumbnail for Long terminal repeat
    type 1 provirus, polyadenylation signals present in the 5' long terminal repeat (LTR) are disregarded while the identical polyadenylation signals present...
    11 KB (1,378 words) - 11:06, 3 December 2023
  • Thumbnail for Primary transcript
    modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly...
    23 KB (3,023 words) - 12:36, 22 February 2024
  • major role in post-transcriptional control of RNAs, such as: splicing, polyadenylation, mRNA stabilization, mRNA localization and translation. Eukaryotic...
    39 KB (4,589 words) - 13:12, 26 August 2023
  • Thumbnail for GLD-2
    specific RNAs, forming a poly(A) tail, which is a process known as polyadenylation. For RNA specificity, GLD-2 associates with an RNA-binding protein...
    10 KB (1,396 words) - 10:08, 17 October 2022
  • Thumbnail for Transcription (biology)
    template-independent addition of adenines at its new 3' end, in a process called polyadenylation. Beyond termination by a terminator sequences (which is a part of a...
    58 KB (6,780 words) - 04:35, 23 May 2024
  • behind another vehicle Surveillance, following someone's movements Polyadenylation, adding a poly(-A) tail to a nucleic acid Tail (disambiguation) This...
    471 bytes (98 words) - 00:11, 15 July 2021
  • Thumbnail for Gene expression
    decapping. Another modification is 3′ cleavage and polyadenylation. They occur if polyadenylation signal sequence (5′- AAUAAA-3′) is present in pre-mRNA...
    81 KB (9,242 words) - 21:24, 22 May 2024
  • Thumbnail for Polymerase
    Eukaryotic cellular (cRdRP; dual-subunit) Template-less RNA elongation Polyadenylation: PAP, PNPase Polymerases are generally split into two superfamilies...
    7 KB (673 words) - 14:35, 24 October 2023
  • Thumbnail for RNA polymerase
    template-independent addition of adenines at its new 3′ end, in a process called polyadenylation. Given that DNA and RNA polymerases both carry out template-dependent...
    41 KB (4,799 words) - 19:34, 17 April 2024
  • the capping process (this kind of mechanism ensures capping, as with polyadenylation). The enzymes for capping can only bind to RNA polymerase II, ensuring...
    16 KB (1,873 words) - 09:28, 17 November 2023
  • Thumbnail for Gene
    Finally, the ends of gene transcripts are defined by cleavage and polyadenylation (CPA) sites, where newly produced pre-mRNA gets cleaved and a string...
    111 KB (12,642 words) - 13:10, 7 June 2024
  • Thumbnail for Macular degeneration
    ARMS2 gene though destabilization of its mRNA through deletion of the polyadenylation signal. ARMS2 protein may localize to the mitochondria and participate...
    90 KB (9,840 words) - 07:29, 23 May 2024
  • Thumbnail for Alternative splicing
    viral proteins. In addition, the primary transcript contained multiple polyadenylation sites, giving different 3' ends for the processed mRNAs. In 1981, the...
    62 KB (7,809 words) - 17:56, 21 May 2024
  • Thumbnail for Facioscapulohumeral muscular dystrophy
    on the type of 4qA allele. A polyadenylation signal is within exon 3. Because exon 3 and its containing polyadenylation signal are not contained within...
    174 KB (16,337 words) - 04:51, 20 May 2024
  • Thumbnail for CPSF3
    Cleavage and polyadenylation specificity factor subunit 3 is a protein that in humans is encoded by the CPSF3 gene. GRCh38: Ensembl release 89: ENSG00000119203...
    6 KB (781 words) - 15:10, 27 March 2024
  • Thumbnail for Cell nucleus
    protein translation. The three main modifications are 5' capping, 3' polyadenylation, and RNA splicing. While in the nucleus, pre-mRNA is associated with...
    87 KB (9,882 words) - 00:14, 1 June 2024
  • encodes one or more polyadenylation signals. Once the signals are transcribed into the mRNA, the proteins cleavage and polyadenylation specificity factor...
    13 KB (1,631 words) - 10:55, 5 June 2024
  • Thumbnail for CPSF2
    Cleavage and polyadenylation specificity factor subunit 2 is a protein that in humans is encoded by the CPSF2 gene. This protein is a subunit of the cleavage...
    9 KB (1,051 words) - 20:19, 13 January 2024
  • Thumbnail for DNA virus
    terminates transcription upon reaching a specific signal, such as a polyadenylation site. dsDNA viruses make use of several mechanisms to replicate their...
    25 KB (2,893 words) - 04:22, 4 July 2023
  • Thumbnail for Rhabdoviridae
    RNA synthesis, it is thought to be involved in methyl capping and polyadenylation activity. P protein plays important and multiple roles during  transcription...
    26 KB (2,776 words) - 14:35, 2 May 2024