Slit-Robo is the name of a cell signaling protein complex with many diverse functions including axon guidance and angiogenesis. Slit refers to a secreted...

well-studied example is the requirement for Slit-Robo signaling in regulation of axonal midline crossing. Slit-Robo signaling is also critical for many neurodevelopmental...

midline glia (in insects) and diffuses outward. Slit/Robo signaling is important in pioneer axon guidance. Slit mutations were first discovered in the...

SLIT-ROBO Rho GTPase activating protein 2C is a protein in humans that is encoded by the SRGAP2C gene. Cortical development gene Slit-Robo Rho GTPase-activating...

SLIT-ROBO Rho GTPase-activating protein 2 (srGAP2), also known as formin-binding protein 2 (FNBP2), is a mammalian protein that in humans is encoded by...

by the Slit-Robo system where Slit proteins act as axonal repellents and Robo proteins (Robo-1, Robo-2, Robo-3) act in conjunction with Slit ligands...

In the Slit/Robo chemoreppelant pathway the C. elegans homologs are Slt-1/Sax-3 whereas the Drosophila homologs are also known as Slit/Robo(1-3). In...

DCC and UNC-5. Slits: Secreted proteins that normally repel growth cones by engaging Robo (Roundabout) class receptors in Slit-Robo cell signaling complexes...

The retraction of the apical process of the RGC is likely mediated by Slit–Robo signaling. RGCs will grow along glial end feet positioned on the inner...

(2004). "Induction of tumor angiogenesis by Slit-Robo signaling and inhibition of cancer growth by blocking Robo activity". Cancer Cell. 4 (1): 19–29. doi:10...

between the inside and outside of the cell membrane Slingshot homolog Slit-Robo and the associated Netrin-Frazzled SMURF1 and SMURF2, SMAD Ubiquitination...

receptors, BMP7, Wnt/dishevelled, EPHB 1–3, Semaphorin/plexin-neuropilin, slit-robo, netrin-frazzled, reelin. Rac, CDC42 and RhoA serve as cytoskeletal regulators...

SLIT-ROBO Rho GTPase-activating protein 1 is an enzyme that in humans is encoded by the SRGAP1 gene. GRCh38: Ensembl release 89: ENSG00000196935 – Ensembl...

preventing Robo/Slit repulsive interactions. Comm expression turns off after the growth cone has crossed the midline; this permits Robo/Slit repulsion...

Gill slits are individual openings to gills, i.e., multiple gill arches, which lack a single outer cover. Such gills are characteristic of cartilaginous...

SLIT-ROBO Rho GTPase-activating protein 3 is an enzyme that in humans is encoded by the SRGAP3 gene. GRCh38: Ensembl release 89: ENSG00000196220 – Ensembl...

by slit-Robo signaling. This is accomplished by the formation of a DCC-Robo complex, which inhibits attractive netrin/DCC signals while allowing slit-Robo...

film RoboCop, the second entry in the RoboCop franchise and the last to feature Weller as RoboCop until he returned in Mortal Kombat 11 (2019), RoboCop:...

in the mechanisms of pioneer axons include netrin, ephrin, semaphorin, Slit-Robo, and Notch. Receptors for these molecules have also been studied. Netrins...

themselves play a role in modulating the astrocytes through Slit-Robo interactions. In the absence of Slit, astrocytic processes do not align correctly, or create...

three obstacles. The third section, at the top of the wall, contains a flat piece of carpet, two obstacles, and a slit. Duke Annual Robo-Climb Competition...

Sandra; Zhao, Zhen; Ma, Le; Tessier-Lavigne, Marc; Marín, Oscar (2012). "Slit/Robo Signaling Modulates the Proliferation of Central Nervous System Progenitors"...

development of the visual system. His group also discovered the role of Slit-Robo signaling in the precise targeting of layers in the optic tectum by ingrowing...

Chen JH, Wu JY, Rao Y, Ornitz DM (August 1999). "The mouse SLIT family: secreted ligands for ROBO expressed in patterns that suggest a role in morphogenesis...

PMID 10102266. S2CID 16810644. Brose K, Bland KS, Wang KH, et al. (1999). "Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive...

vertebrates typically develop in the walls of the pharynx, along a series of gill slits opening to the exterior. Most species employ a counter-current exchange...

while watching RoboCop 2: "The first girl I killed was from a 'RoboCop' movie... I seen him cut somebody's throat then take the knife and slit down the chest...

Chromatophore Fins dorsal fin Gill branchial arch gill raker gill slit pharyngeal arch pharyngeal slit pseudobranch Glossohyal Jaw hyomandibula pharyngeal jaw Leydig's...

Chromatophore Fins dorsal fin Gill branchial arch gill raker gill slit pharyngeal arch pharyngeal slit pseudobranch Glossohyal Jaw hyomandibula pharyngeal jaw Leydig's...

Chromatophore Fins dorsal fin Gill branchial arch gill raker gill slit pharyngeal arch pharyngeal slit pseudobranch Glossohyal Jaw hyomandibula pharyngeal jaw Leydig's...