• Cephalosporins are a broad class of bactericidal antibiotics that include the β-lactam ring and share a structural similarity and mechanism of action with...
    33 KB (4,053 words) - 20:21, 18 September 2024
  • Thumbnail for Drug discovery
    of antiandrogens Discovery and development of cephalosporins Retrometabolic drug design "The drug development process". US Food and Drug Administration...
    59 KB (6,793 words) - 20:39, 29 May 2025
  • Thumbnail for Cephalosporin
    of β-lactam antibiotics called cephems. Cephalosporins were discovered in 1945, and first sold in 1964. The aerobic mold which yielded cephalosporin C...
    36 KB (2,420 words) - 10:59, 26 May 2025
  • Thumbnail for Β-Lactam antibiotic
    wall Discovery and development of cephalosporins History of penicillin Nitrocefin Holten KB, Onusko EM (August 2000). "Appropriate prescribing of oral...
    34 KB (3,708 words) - 22:37, 29 May 2025
  • Thumbnail for Giuseppe Brotzu
    Giuseppe Brotzu (category Members of the Regional Council of Sardinia)
    PMID 10208039. Cephalosporin Discovery and development of cephalosporins Bo G (2000). "Giuseppe Brotzu and the discovery of cephalosporins". Clinical Microbiology...
    4 KB (321 words) - 06:24, 1 June 2025
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    discovery and production of many other cephalosporins. Cephalosporins are drugs used for some people who are allergic to penicillin. Cephalosporins are...
    5 KB (393 words) - 14:54, 8 March 2024
  • Thumbnail for Ceftriaxone
    Ceftriaxone (category Cephalosporin antibiotics)
    Providencia, and Serratia, have the ability to become resistant through the development of cephalosporinases (enzymes that hydrolyze cephalosporins and render...
    36 KB (3,187 words) - 13:48, 1 June 2025
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    Penicillins, Amino, Cephalosporins, Second Generation, Cephalosporins, Third Generation, Cephalosporins, Other, Penicillins, Extended-Spectrum, Aminoglycosides...
    36 KB (3,671 words) - 05:58, 23 May 2025
  • Thumbnail for History of penicillin
    history of penicillin follows observations and discoveries of evidence of antibiotic activity of the mould Penicillium that led to the development of penicillins...
    132 KB (16,733 words) - 13:16, 22 May 2025
  • Thumbnail for Carbapenem
    (MDR) bacterial infections. Similar to penicillins and cephalosporins, carbapenems are members of the beta-lactam antibiotics drug class, which kill bacteria...
    31 KB (3,527 words) - 20:16, 29 May 2025
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    claims. The aftermath of World War II saw an explosion in the discovery of new classes of antibacterial drugs including the cephalosporins (developed by Eli...
    124 KB (13,072 words) - 01:05, 31 May 2025
  • Thumbnail for Cefoxitin
    Cefoxitin (category Cephalosporin antibiotics)
    cephalosporins. Cefoxitin requires a prescription and as of 2010 is sold under the brand name Mefoxin by Bioniche Pharma, LLC. The generic version of...
    27 KB (2,636 words) - 20:18, 29 May 2025
  • Thumbnail for Cefpodoxime
    Cefpodoxime (category Cephalosporin antibiotics)
    gonorrhea. It also finds use as oral continuation therapy when intravenous cephalosporins (such as ceftriaxone) are no longer necessary for continued treatment...
    7 KB (406 words) - 17:44, 7 April 2025
  • Thumbnail for Thienamycin
    (penicillins, cephalosporins). Production of classic β-lactams in both fungi and bacteria occur through two steps: First, the condensation of l-cysteine...
    12 KB (1,219 words) - 09:30, 5 January 2025
  • Edward Abraham (category Fellows of the American Academy of Arts and Sciences)
    commercially sold cephalosporin antibiotic Cefalotin sold by Eli Lilly and Company. There are now five generations of cephalosporins, of which some are among...
    17 KB (1,734 words) - 20:44, 26 May 2025
  • Thumbnail for Beta-lactamase
    Beta-lactamase (category Enzymes of known structure)
    multi-resistance to beta-lactam antibiotics such as penicillins, cephalosporins, cephamycins, monobactams and carbapenems (ertapenem), although carbapenems are relatively...
    53 KB (6,271 words) - 20:07, 29 May 2025
  • Thumbnail for Penicillin
    Penicillin (category Drugs developed by Eli Lilly and Company)
    avoidance, 90% of these patients can eventually tolerate penicillin. Additionally, those with penicillin allergies can usually tolerate cephalosporins (another...
    100 KB (10,776 words) - 21:50, 29 May 2025
  • Thumbnail for Impetigo
    Alternatively, amoxicillin combined with clavulanate potassium, cephalosporins (first-generation) and many others may also be used as an antibiotic treatment...
    21 KB (1,942 words) - 05:47, 25 February 2025
  • mutilus) and Clitopilus passeckerianus (formerly Pleurotus passeckerianus). Cephalosporins were first sold in 1964, the mold which yielded cephalosporin C was...
    20 KB (1,812 words) - 23:08, 23 May 2025
  • Thumbnail for Latamoxef
    Latamoxef (category Cephalosporin antibiotics)
    antibiotic usually grouped with the cephalosporins. In oxacephems such as latamoxef, the sulfur atom of the cephalosporin core is replaced with an oxygen...
    8 KB (710 words) - 19:20, 11 February 2025
  • Thumbnail for Haemophilus influenzae
    ampicillin to cephalosporins, however further resistance to cephalosporins has occurred due to changes in the transpeptidase domain of penicillin binding...
    45 KB (4,829 words) - 02:13, 30 May 2025
  • Thumbnail for Antibiotic
    (penicillins and cephalosporins) or the cell membrane (polymyxins), or interfere with essential bacterial enzymes (rifamycins, lipiarmycins, quinolones, and sulfonamides)...
    157 KB (14,722 words) - 19:58, 29 May 2025
  • Thumbnail for Alexander Fleming
    Alexander Fleming (category Fellows of the Royal College of Physicians of Edinburgh)
    Penicillins and Cephalosporins. Academic Press. pp. xxii. ISBN 978-1-4832-7719-6. Ward, John W.; Warren, Christian (2006). Silent Victories: The History and Practice...
    68 KB (7,629 words) - 10:50, 28 May 2025
  • Thumbnail for Cefotaxime
    Cefotaxime (category Cephalosporin antibiotics)
    antibiotic in the third-generation class of cephalosporins, cefotaxime is active against numerous Gram-positive and Gram-negative bacteria, including several...
    18 KB (1,677 words) - 20:18, 29 May 2025
  • Thumbnail for Proteus mirabilis
    from tetracycline and nitrofurantoin, but 10–20% of P. mirabilis strains are also resistant to first-generation cephalosporins and ampicillin. P. mirabilis...
    12 KB (1,254 words) - 15:44, 30 April 2025
  • Thumbnail for Howard Florey
    Howard Florey (category Fellows of the American Academy of Arts and Sciences)
    pp. 269–272. Bo G (2000). "Giuseppe Brotzu and the discovery of cephalosporins". Clinical Microbiology and Infection. 6 (Suppl 3): 6–9. doi:10.1111/j...
    114 KB (13,612 words) - 13:56, 29 March 2025
  • Thumbnail for Ciprofloxacin
    worsening muscle weakness. Rates of side effects appear to be higher than some groups of antibiotics such as cephalosporins but lower than others such as...
    66 KB (6,652 words) - 20:22, 29 May 2025
  • Due to the discovery of penicillin by Alexander Fleming, and the efforts of Florey and Chain in 1938, large-scale, pharmaceutical production of antibiotics...
    22 KB (2,830 words) - 20:01, 23 May 2025
  • Thumbnail for Typhoid fever
    "Treatment of typhoid fever and other systemic salmonelloses with cefotaxime, ceftriaxone, cefoperazone, and other newer cephalosporins". Reviews of Infectious...
    98 KB (10,766 words) - 22:09, 21 May 2025
  • Thumbnail for Natural product
    including penicillin and the cephalosporins (antibacterial drugs from Penicillium rubens and Cephalosporium acremonium, respectively) and griseofulvin (an...
    116 KB (12,419 words) - 12:19, 7 May 2025