Cephalosporins are a broad class of bactericidal antibiotics that include the β-lactam ring and share a structural similarity and mechanism of action with...
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of antiandrogens Discovery and development of cephalosporins Retrometabolic drug design "The drug development process". US Food and Drug Administration...
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of β-lactam antibiotics called cephems. Cephalosporins were discovered in 1945, and first sold in 1964. The aerobic mold which yielded cephalosporin C...
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Β-Lactam antibiotic (section Mechanism of action)
wall Discovery and development of cephalosporins History of penicillin Nitrocefin Holten KB, Onusko EM (August 2000). "Appropriate prescribing of oral...
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Giuseppe Brotzu (category Members of the Regional Council of Sardinia)
PMID 10208039. Cephalosporin Discovery and development of cephalosporins Bo G (2000). "Giuseppe Brotzu and the discovery of cephalosporins". Clinical Microbiology...
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discovery and production of many other cephalosporins. Cephalosporins are drugs used for some people who are allergic to penicillin. Cephalosporins are...
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Ceftriaxone (category Cephalosporin antibiotics)
Providencia, and Serratia, have the ability to become resistant through the development of cephalosporinases (enzymes that hydrolyze cephalosporins and render...
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Penicillins, Amino, Cephalosporins, Second Generation, Cephalosporins, Third Generation, Cephalosporins, Other, Penicillins, Extended-Spectrum, Aminoglycosides...
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history of penicillin follows observations and discoveries of evidence of antibiotic activity of the mould Penicillium that led to the development of penicillins...
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Carbapenem (section Spectrum of activity)
(MDR) bacterial infections. Similar to penicillins and cephalosporins, carbapenems are members of the beta-lactam antibiotics drug class, which kill bacteria...
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Pharmaceutical industry (redirect from History of the pharmaceutical industry)
claims. The aftermath of World War II saw an explosion in the discovery of new classes of antibacterial drugs including the cephalosporins (developed by Eli...
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Cefoxitin (category Cephalosporin antibiotics)
cephalosporins. Cefoxitin requires a prescription and as of 2010 is sold under the brand name Mefoxin by Bioniche Pharma, LLC. The generic version of...
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Cefpodoxime (category Cephalosporin antibiotics)
gonorrhea. It also finds use as oral continuation therapy when intravenous cephalosporins (such as ceftriaxone) are no longer necessary for continued treatment...
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Thienamycin (section Mechanism of action)
(penicillins, cephalosporins). Production of classic β-lactams in both fungi and bacteria occur through two steps: First, the condensation of l-cysteine...
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Edward Abraham (category Fellows of the American Academy of Arts and Sciences)
commercially sold cephalosporin antibiotic Cefalotin sold by Eli Lilly and Company. There are now five generations of cephalosporins, of which some are among...
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Beta-lactamase (category Enzymes of known structure)
multi-resistance to beta-lactam antibiotics such as penicillins, cephalosporins, cephamycins, monobactams and carbapenems (ertapenem), although carbapenems are relatively...
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Penicillin (category Drugs developed by Eli Lilly and Company)
avoidance, 90% of these patients can eventually tolerate penicillin. Additionally, those with penicillin allergies can usually tolerate cephalosporins (another...
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Impetigo (section Signs and symptoms)
Alternatively, amoxicillin combined with clavulanate potassium, cephalosporins (first-generation) and many others may also be used as an antibiotic treatment...
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mutilus) and Clitopilus passeckerianus (formerly Pleurotus passeckerianus). Cephalosporins were first sold in 1964, the mold which yielded cephalosporin C was...
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Latamoxef (category Cephalosporin antibiotics)
antibiotic usually grouped with the cephalosporins. In oxacephems such as latamoxef, the sulfur atom of the cephalosporin core is replaced with an oxygen...
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ampicillin to cephalosporins, however further resistance to cephalosporins has occurred due to changes in the transpeptidase domain of penicillin binding...
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Antibiotic (redirect from History of antibiotics)
(penicillins and cephalosporins) or the cell membrane (polymyxins), or interfere with essential bacterial enzymes (rifamycins, lipiarmycins, quinolones, and sulfonamides)...
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Alexander Fleming (category Fellows of the Royal College of Physicians of Edinburgh)
Penicillins and Cephalosporins. Academic Press. pp. xxii. ISBN 978-1-4832-7719-6. Ward, John W.; Warren, Christian (2006). Silent Victories: The History and Practice...
68 KB (7,629 words) - 10:50, 28 May 2025
Cefotaxime (category Cephalosporin antibiotics)
antibiotic in the third-generation class of cephalosporins, cefotaxime is active against numerous Gram-positive and Gram-negative bacteria, including several...
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from tetracycline and nitrofurantoin, but 10–20% of P. mirabilis strains are also resistant to first-generation cephalosporins and ampicillin. P. mirabilis...
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Howard Florey (category Fellows of the American Academy of Arts and Sciences)
pp. 269–272. Bo G (2000). "Giuseppe Brotzu and the discovery of cephalosporins". Clinical Microbiology and Infection. 6 (Suppl 3): 6–9. doi:10.1111/j...
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Ciprofloxacin (section Spectrum of activity)
worsening muscle weakness. Rates of side effects appear to be higher than some groups of antibiotics such as cephalosporins but lower than others such as...
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Due to the discovery of penicillin by Alexander Fleming, and the efforts of Florey and Chain in 1938, large-scale, pharmaceutical production of antibiotics...
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"Treatment of typhoid fever and other systemic salmonelloses with cefotaxime, ceftriaxone, cefoperazone, and other newer cephalosporins". Reviews of Infectious...
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Natural product (redirect from List of natural product drugs)
including penicillin and the cephalosporins (antibacterial drugs from Penicillium rubens and Cephalosporium acremonium, respectively) and griseofulvin (an...
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