The p75 neurotrophin receptor (p75NTR) was first identified in 1973 as the low-affinity nerve growth factor receptor (LNGFR) before discovery that p75NTR...
37 KB (4,235 words) - 09:21, 21 December 2023
Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
23 KB (2,786 words) - 23:53, 26 April 2024
responding to this growth factor, TrkB (pronounced "Track B") and the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). It may...
45 KB (5,339 words) - 00:15, 22 March 2024
Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase receptor type 1, or TRK1-transforming...
27 KB (3,264 words) - 05:43, 13 April 2024
High affinity neurotrophin receptors Ephrin receptors Integrins Low Affinity Nerve Growth Factor Receptor NMDA receptor Several Immune receptors Toll-like...
21 KB (2,456 words) - 22:14, 21 November 2023
Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
58 KB (6,923 words) - 01:30, 3 May 2024
Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
17 KB (1,735 words) - 03:22, 28 February 2024
This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. FGFR2 has important...
14 KB (1,748 words) - 14:34, 11 December 2023
neurotrophic factor receptors are the p75 and the "Trk" families of Tyrosine kinases receptors. p75 is a low affinity neurotrophin receptor, to which all...
5 KB (670 words) - 17:28, 23 January 2021
Neurotrophin-3 (redirect from Neurotrophic Factor-3)
binds a second-receptor type besides Trk receptors, called the LNGFR (for "low affinity nerve growth factor receptor). TrkC is a receptor tyrosine kinase...
14 KB (1,816 words) - 04:39, 31 October 2023
Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor, type...
40 KB (4,321 words) - 10:20, 23 March 2024
is one other NT-3 receptor family besides the Trks (TrkC & TrkB), called the "LNGFR" (for "low affinity nerve growth factor receptor"). As opposed to TrkC...
32 KB (3,936 words) - 03:00, 29 January 2024
The binding of TNF to its receptor and its displacement by LT confirmed the functional homology between the two factors. The sequential and functional...
52 KB (6,302 words) - 07:19, 27 April 2024
Neurotrophin (redirect from Neuronal growth associated protein)
of receptors for neurotrophins: p75 and the "Trk" family of Tyrosine kinases receptors. Nerve growth factor (NGF), the prototypical growth factor, is...
27 KB (3,069 words) - 02:53, 24 May 2024
Fibroblast growth factor receptor 3 is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster of differentiation...
17 KB (1,955 words) - 06:59, 15 April 2024
Placental growth factor (PlGF) is a protein that in humans is encoded by the PGF gene. Placental growth factor (PGF) is a member of the VEGF (vascular...
15 KB (1,923 words) - 12:01, 27 September 2023
Somatostatin (redirect from Growth Hormone Inhibatory Hormone)
Pasireotide is somatostatin analog with a 40-fold increased affinity to somatostatin receptor 5 compared to other somatostatin analogs. Six somatostatin...
23 KB (2,566 words) - 00:09, 5 April 2024
into co-receptors for p75, such as the sortilin co-receptor, has implicated sortilin in connection to neurotrophins, a type of nerve growth factor. The p75...
21 KB (3,129 words) - 20:16, 11 July 2023
Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
40 KB (4,578 words) - 20:20, 10 March 2024
TRAF2 (redirect from Tnf receptor-associated factor 2)
CD40, CFLAR, CHUK, Caveolin 1, EDARADD, HIVEP3, IKK2, Low affinity nerve growth factor receptor, MAP3K14, MAP3K1, MAP3K7IP2, MAP4K2, MAP4K5, RANK, RIPK1...
29 KB (3,427 words) - 04:28, 25 December 2023
gene. NGFRAP1 has been shown to interact with YWHAE and Low affinity nerve growth factor receptor. GRCh38: Ensembl release 89: ENSG00000166681 – Ensembl...
6 KB (847 words) - 23:15, 4 September 2022
successful NMDA receptor antagonists for neurodegenerative diseases continued and focused on developing low affinity blockers. However the affinity could not...
107 KB (12,051 words) - 23:49, 26 April 2024
inhibitory factor receptor Leukocyte extravasation Leukocyte-promoting factor Linear epitope Lipid A Lipopolysaccharide binding protein Low-affinity nerve growth...
13 KB (1,237 words) - 01:24, 15 January 2024
OECs have been identified with high or low cell surface expression of low-affinity nerve growth factor receptor (p75). Neuroscience Neuroglia Olfaction...
18 KB (2,259 words) - 09:20, 18 July 2023
Integrin (redirect from Integrin receptor)
"beta1A integrin expression is required for type 1 insulin-like growth factor receptor mitogenic and transforming activities and localization to focal...
36 KB (3,929 words) - 08:32, 12 May 2024
The μ-opioid receptors (MOR) are a class of opioid receptors with a high affinity for enkephalins and beta-endorphin, but a low affinity for dynorphins...
22 KB (2,424 words) - 08:47, 18 May 2024
PMID 2823383. Lynch CJ, Steer ML (Apr 1981). "Evidence for high and low affinity alpha 2-receptors. Comparison of [3H]norepinephrine and [3H]phentolamine binding...
12 KB (1,307 words) - 05:44, 17 May 2024
Prolactin (redirect from Receptors, prolactin)
cycle-related functions as a growth-, differentiating- and anti-apoptotic factor. As a growth factor, binding to cytokine-like receptors, it influences hematopoiesis...
56 KB (5,820 words) - 00:14, 19 May 2024
has been shown to interact with: E2F1, HNRNPU, IL1A, Low affinity nerve growth factor receptor, NUCB2, and P53 ENSG00000288364 GRCh38: Ensembl release...
11 KB (1,275 words) - 18:10, 27 December 2023
LRP1 (redirect from Low density lipoprotein receptor-related protein 1)
Low density lipoprotein receptor-related protein 1 (LRP1), also known as alpha-2-macroglobulin receptor (A2MR), apolipoprotein E receptor (APOER) or cluster...
32 KB (3,564 words) - 02:52, 28 March 2024