Base excision repair (BER) is a cellular mechanism, studied in the fields of biochemistry and genetics, that repairs damaged DNA throughout the cell cycle...

mutagens. Three excision repair pathways exist to repair single stranded DNA damage: Nucleotide excision repair (NER), base excision repair (BER), and DNA...

response mechanisms (base excision repair (BER), nucleotide excision repair (NER), DNA mismatch repair (MMR), homologous recombination repair (HR), non-homologous...

Stage 3: Base excision DNA repair. The intermediate products of demethylation are catalysed by specific enzymes of the base excision DNA repair pathway...

accurate base excision repair or translesion synthesis without mutation. G:C to T:A transversions occurred in 5.9% of the clones, single base deletions...

Mouse models of nucleotide-excision–repair syndromes reveal a striking correlation between the degree to which specific DNA repair pathways are compromised...

base excision repair. These AP sites are removed by AP endonucleases, which effect single strand breaks around the site. Nucleotide excision repair,...

accurate base excision repair or translesion synthesis without mutation. G:C to T:A transversions occurred in 5.9% of the clones, single base deletions...

structure is formed, the base excision repair enzyme OGG1 targets 8-OHdG and binds to the lesion without immediate excision. OGG1, present at a 5mCp-8-OHdG...

kinases perform repair regulation at three levels - via PTMs, at the level of chromatin, and at the level of the nucleus. Base excision repair (BER) is responsible...

repair of double strand breaks by homologous recombination or non-homologous end joining, repair of single nucleotide damages by base excision repair...

(often some of both). But elimination of any gene essential for base excision repair kills the embryo—it is too lethal to display symptoms (much less...

enrichment for transversion mutations (G:C>T:A) has been associated with base excision repair (BER) deficiency and linked to defective MUTYH, a DNA glycosylase...

involved in base excision repair. It is found in bacterial, archaeal and eukaryotic species. OGG1 is the primary enzyme responsible for the excision of 8-oxoguanine...

intermediates in base excision repair. In this process, a DNA glycosylase recognizes a damaged base and cleaves the N-glycosidic bond to release the base, leaving...

The DNA repair pathways in mammalian mitochondria include base excision repair, double-strand break repair, direct reversal and mismatch repair. Alternatively...

interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate,...

are a family of enzymes involved in base excision repair, classified under EC number EC 3.2.2. Base excision repair is the mechanism by which damaged bases...

DNA molecules by cleaving the N-glycosidic bond and initiating the base-excision repair (BER) pathway. The human gene encodes one of several uracil-DNA glycosylases...

chromatin-associated protein that is required for normal base excision repair and double-strand break repair of DNA damage in mammalian cells. Deficiency of SIRT6...

DNA. XRCC1 is involved in single-strand break repair, base excision repair and nucleotide excision repair. As reviewed by London, XRCC1 protein has three...

(hMYH) physically interacts with proteins involved in long patch DNA base excision repair". The Journal of Biological Chemistry. 276 (8): 5547–55. doi:10.1074/jbc...

bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species (ROS) and introducing...

encodes DNA ligase 1, which functions in DNA replication and the base excision repair process. Eukaryotic DNA ligase 1 catalyzes a reaction that is chemically...

the process of base excision repair are sensitive to bile salts. This indicates that wild-type S. enterica uses base excision repair to remove DNA damages...

suggests that other forms of DNA repair including non-homologous end joining, nucleotide excision repair and base excision repair also depend on RECQL4 function...

DNA excision repair protein ERCC-6 (also CS-B protein) is a protein that in humans is encoded by the ERCC6 gene. The ERCC6 gene is located on the long...

recombination. PCNA interacts with many proteins. Apoptotic factors ATPases Base excision repair enzymes Cell-cycle regulators Chromatin remodeling factor Clamp loader...

natural host. Three putative DNA base excision repair enzymes were characterized from Mimivirus. The base excision repair (BER) pathway was experimentally...

endonuclease is an enzyme that is involved in the DNA base excision repair pathway (BER). Its main role in the repair of damaged or mismatched nucleotides in DNA...