• Thumbnail for Complement system
    The complement system, also known as complement cascade, is a part of the humoral, innate immune system and enhances (complements) the ability of antibodies...
    43 KB (5,123 words) - 01:37, 20 April 2025
  • Two's complement is the most common method of representing signed (positive, negative, and zero) integers on computers, and more generally, fixed point...
    46 KB (6,025 words) - 03:18, 18 April 2025
  • specific computer represents numbers. A ones' complement system or ones' complement arithmetic is a system in which negative numbers are represented by...
    11 KB (1,341 words) - 22:27, 15 June 2024
  • Thumbnail for Immune system
    include phagocytosis, antimicrobial peptides called defensins, and the complement system. Jawed vertebrates, including humans, have even more sophisticated...
    119 KB (13,520 words) - 22:39, 15 April 2025
  • Thumbnail for Classical complement pathway
    classical complement pathway is one of three pathways which activate the complement system, which is part of the immune system. The classical complement pathway...
    16 KB (1,877 words) - 16:06, 20 January 2025
  • immunity that is mediated by macromolecules – including secreted antibodies, complement proteins, and certain antimicrobial peptides – located in extracellular...
    17 KB (1,673 words) - 20:08, 9 February 2025
  • Thumbnail for Alternative complement pathway
    pathway is a type of cascade reaction of the complement system and is a component of the innate immune system, a natural defense against infections. The...
    7 KB (865 words) - 13:08, 7 September 2024
  • Complement component 4 (C4), in humans, is a protein involved in the intricate complement system, originating from the human leukocyte antigen (HLA) system...
    35 KB (4,189 words) - 16:19, 7 November 2023
  • A complement receptor is a membrane-bound receptor belonging to the complement system, which is part of the innate immune system. Complement receptors...
    6 KB (376 words) - 06:42, 5 March 2024
  • Thumbnail for Complement component 3
    Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the...
    13 KB (1,556 words) - 13:28, 23 September 2024
  • Thumbnail for Innate immune system
    involved organs/tissues. The complement system is a biochemical cascade of the immune system that helps, or "complements", the ability of antibodies to...
    44 KB (4,847 words) - 15:03, 8 May 2025
  • Thumbnail for Complement deficiency
    Complement deficiency is an immunodeficiency of absent or suboptimal functioning of one of the complement system proteins. Because of redundancies in the...
    15 KB (1,248 words) - 18:12, 28 January 2025
  • Thumbnail for Complement membrane attack complex
    the activation of the host's complement system, and as such is an effector of the immune system. Antibody-mediated complement activation leads to MAC deposition...
    9 KB (1,147 words) - 08:12, 30 December 2024
  • Thumbnail for C3a (complement)
    inflammatory function (C3a desarginine). C3a is an effector of the complement system with a range of functions including T cell activation and survival...
    17 KB (2,036 words) - 05:36, 19 February 2024
  • Aggregate complementation, the separation of pitch-class collections into complementary sets Complementary color, in the visual arts Complement system (immunology)...
    3 KB (328 words) - 00:28, 17 April 2025
  • Thumbnail for Complement component 1q
    The complement component 1q (or simply C1q) is a protein complex involved in the complement system, which is part of the innate immune system. C1q together...
    7 KB (691 words) - 18:41, 21 December 2023
  • Complement control proteins are proteins that interact with components of the complement system. The complement system is tightly regulated by a network...
    16 KB (1,942 words) - 09:32, 27 February 2024
  • Thumbnail for Complement receptor 1
    characterized. In primates, CR1 serves as the main system for processing and clearance of complement opsonized immune complexes. It has been shown that...
    22 KB (2,904 words) - 06:22, 17 August 2024
  • formation of a membrane attack complex (MAC) and target cell lysis. Complement system is efficiently activated by human IgG1, IgG3 and IgM antibodies, weakly...
    8 KB (957 words) - 17:30, 28 April 2024
  • Thumbnail for Complement component 2
    the complement system, acting as a multi-domain serine protease. Deficiency of C2 has been associated with certain autoimmune diseases. The Complement system...
    16 KB (2,068 words) - 18:45, 14 January 2024
  • Thumbnail for C-reactive protein
    dying cells (and some types of bacteria) in order to activate the complement system via C1q. CRP is synthesized by the liver in response to factors released...
    48 KB (5,497 words) - 07:42, 15 April 2025
  • Thumbnail for Anaphylatoxin
    Anaphylatoxin (category Complement system)
    Anaphylatoxins, or complement peptides, are fragments (C3a, C4a and C5a) that are produced as part of the activation of the complement system. Complement components...
    6 KB (607 words) - 15:39, 3 December 2023
  • Total complement activity (TCA) refers to a series of tests that determine the functioning of the complement system in an individual. A variety of tests...
    5 KB (559 words) - 15:53, 23 January 2024
  • Thumbnail for Antibody
    recognize multiple distinct (unrelated) antigens. These can work with the complement system in the earliest phases of an immune response to help facilitate clearance...
    126 KB (13,957 words) - 01:37, 19 March 2025
  • Thumbnail for Complement component 5
    Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...
    9 KB (1,114 words) - 05:29, 8 January 2024
  • attack, kidney failure, and death. The complement system activation may be due to mutations in the complement regulatory proteins (factor H, factor I...
    38 KB (4,164 words) - 22:37, 9 November 2024
  • Thumbnail for Complement receptor 2
    complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d. B cells express CR2 on their surfaces, allowing the complement system...
    14 KB (1,829 words) - 16:40, 11 January 2025
  • Thumbnail for Complement fixation test
    DNA-based methods of pathogen detection, particularly PCR. The complement system is a system of serum proteins that react with antigen-antibody complexes...
    4 KB (520 words) - 02:17, 19 June 2024
  • Thumbnail for C3-convertase
    serine proteases and is necessary in innate immunity as a part of the complement system which eventuate in opsonisation of particles, release of inflammatory...
    10 KB (1,319 words) - 01:19, 29 November 2024
  • Thumbnail for Complement factor B
    Complement factor B is a protein that in humans is encoded by the CFB gene. This gene encodes complement factor B, a component of the alternative pathway...
    9 KB (1,095 words) - 07:56, 3 January 2024