Directed evolution (DE) is a method used in protein engineering that mimics the process of natural selection to steer proteins or nucleic acids toward...

The term directed evolution is used within the transhumanist community to refer to the idea of applying the principles of directed evolution and experimental...

Evolution is the change in the heritable characteristics of biological populations over successive generations. It occurs when evolutionary processes...

are used for the next round of mutagenesis. Protein Sequence space Directed evolution Protein engineering High-dimensional space DePristo, Mark A.; Weinreich...

development of directed evolution methods was honored in 2018 with the awarding of the Nobel Prize in Chemistry to Frances Arnold for evolution of enzymes...

selection as the organizing mechanism in evolution for a rectilinear (straight-line) model of directed evolution. With the emergence of the modern synthesis...

"Orthogenesis" (goal-directed evolution), "nomogenesis" (evolution according to fixed law), "emergent evolution", "creative evolution", and others. The Jesuit...

general strategies for protein engineering: rational protein design and directed evolution. These methods are not mutually exclusive; researchers will often...

Steinberg, Barrett E. (16 April 2020). "SMOOT libraries and phage-induced directed evolution of Cas9 to engineer reduced off-target activity". PLOS ONE. 15 (4):...

was awarded the Nobel Prize in Chemistry for pioneering the use of directed evolution to engineer enzymes. In 2019, Alphabet Inc. announced that Arnold...

the function of a protein. Directed evolution is the attempt to engineer proteins using methods inspired by molecular evolution. Change at one locus begins...

synthetic biology.). Auxotrophy Biological dark matter Body plan Directed evolution Expanded genetic code Foldamer Hachimoji DNA Hypothetical types of...

Experimental evolution is the use of laboratory experiments or controlled field manipulations to explore evolutionary dynamics. Evolution may be observed...

identified by directed evolution. More recently (2024), snowflake yeast were subject to over 3,000 generations of further directed evolution, forming macroscopic...

greater control over human biological nature through a process called directed evolution. Some thinkers believe that this may shatter our sense of self, and...

in vitro random recombination method to generate mutant genes for directed evolution and to enable a rapid increase in DNA library size. Three procedures...

Underworld: Evolution is a 2006 American action horror film directed by Len Wiseman from a screenplay by Danny McBride, based on a story by Wiseman and...

Saturation mutagenesis is commonly used to generate variants for directed evolution. Sequence saturation mutagenesis Reetz, M. T.; Carballeira J. D. (2007)...

Phage-assisted continuous evolution (PACE) is a phage-based technique for the automated directed evolution of proteins. It relies on relating the desired...

Teleology in biology is the use of the language of goal-directedness in accounts of evolutionary adaptation, which some biologists and philosophers of...

experimental evolution to the control of human evolution. Law professor Maxwell Mehlman has said that "for transhumanists, directed evolution is likened...

be transformed after any diversification step. This allows facile directed evolution of binding proteins over several generations. A prerequisite for the...

design by directed evolution". Annu Rev Biophys. 37: 153–73. doi:10.1146/annurev.biophys.37.032807.125832. PMID 18573077. Maher B. (2009). "Evolution: Biology's...

The Mitsubishi Lancer Evolution, popularly referred to as the "Evo", is a sports sedan and rally car based on the Lancer that was manufactured by Japanese...

Alternatives to Darwinian evolution have been proposed by scholars investigating biology to explain signs of evolution and the relatedness of different...

Islamic views on evolution are diverse, ranging from theistic evolution to Old Earth creationism. Some Muslims around the world believe "humans and other...

use. Due to the iterative nature of directed evolution and the necessity for large libraries, directed evolution at the macroscale can be a costly endeavor...

X-Men: Evolution is an American animated television series about the Marvel Comics superhero team X-Men. In this incarnation, many of the characters are...

DNA processes, and the virus has also been used for phage display, directed evolution, nanostructures and nanotechnology applications. The phage coat is...

Recurring cultural, political, and theological rejection of evolution by religious groups exists regarding the origins of the Earth, of humanity, and...