• Programmed cell death (PCD) sometimes referred to as cell, or cellular suicide is the death of a cell as a result of events inside of a cell, such as apoptosis...
    57 KB (6,843 words) - 14:01, 27 April 2025
  • Thumbnail for Programmed cell death protein 1
    Programmed cell death protein 1 (PD-1), (CD279 cluster of differentiation 279). PD-1 is a protein encoded in humans by the PDCD1 gene. PD-1 is a cell...
    39 KB (4,995 words) - 22:41, 14 December 2024
  • Thumbnail for Cell death
    pathways of programmed cell death have been discovered. Called "non-apoptotic programmed cell-death" (or "caspase-independent programmed cell-death"), these...
    21 KB (2,738 words) - 13:17, 23 April 2025
  • Thumbnail for PD-L1
    Programmed death-ligand 1 (PD-L1) also known as cluster of differentiation 274 (CD274) or B7 homolog 1 (B7-H1) is a protein that in humans is encoded by...
    25 KB (3,052 words) - 15:34, 14 September 2024
  • Thumbnail for Activation-induced cell death
    AICD (activation-induced cell death) is programmed cell death caused by the interaction of Fas receptors (Fas, CD95) and Fas ligands (FasL, CD95 ligand)...
    4 KB (475 words) - 17:58, 21 April 2025
  • Thumbnail for Apoptosis
     'falling off') is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast...
    94 KB (10,857 words) - 05:19, 12 May 2025
  • the intrinsic pathway that block programmed cell death, which can frequently lead to cancer or other effects for the cell if mutated or improperly regulated...
    13 KB (1,569 words) - 04:02, 12 January 2025
  • Thumbnail for PDCD1LG2
    Programmed cell death 1 ligand 2 (also known as PD-L2, B7-DC) is a protein that in humans is encoded by the PDCD1LG2 gene. PDCD1LG2 has also been designated...
    19 KB (2,037 words) - 23:10, 23 March 2025
  • Ischemic cell death, or oncosis, is a form of accidental cell death. The process is characterized by an ATP depletion within the cell leading to impairment...
    7 KB (866 words) - 22:52, 12 December 2024
  • Thumbnail for The Hallmarks of Cancer
    of programmed cell death (cell suicide), the mechanism by which cells are programmed to die in the event they become damaged. Cancer cells are characteristically...
    37 KB (4,314 words) - 19:48, 22 April 2025
  • Autophagic cell death (ACD) is a controversial form of programmed cell death that is morphologically distinct from apoptosis and necrosis. While autophagy...
    2 KB (211 words) - 19:38, 31 March 2025
  • Thumbnail for Bleb (cell biology)
    seen in apoptosis (programmed cell death), but they are also seen in other non-apoptotic functions, including apocrine secretion (cell secretion by disintegration...
    18 KB (1,990 words) - 15:46, 4 December 2024
  • Thumbnail for Sjögren's disease
    lymphomagenesis (origin of lymphoma). Dysregulation of apoptosis (programmed cell death) is believed to play a role in the pathogenesis of a variety of...
    90 KB (9,425 words) - 14:37, 13 May 2025
  • Thumbnail for Mitochondrion
    energy capability before committing to another round of cell division. Programmed cell death (PCD) is crucial for various physiological functions, including...
    169 KB (18,655 words) - 17:36, 16 May 2025
  • Thumbnail for Necroptosis
    contrast to orderly, programmed cell death via apoptosis. The discovery of necroptosis showed that cells can execute necrosis in a programmed fashion and that...
    14 KB (1,667 words) - 09:21, 5 November 2024
  • Thumbnail for Caenorhabditis elegans
    examples of asymmetric cell divisions, and the worm is a very popular model system for studying developmental biology. Programmed cell death (apoptosis) eliminates...
    95 KB (10,941 words) - 13:31, 3 May 2025
  • Thumbnail for Bcl-2 family
    family is most notable for their regulation of apoptosis, a form of programmed cell death, at the mitochondrion. The Bcl-2 family proteins consists of members...
    16 KB (2,148 words) - 20:47, 18 March 2025
  • History of apoptosis research (category Programmed cell death)
    Apoptosis is the process of programmed cell death. From its early conceptual beginnings in the 1950s, it has exploded as an area of research within the...
    12 KB (1,614 words) - 14:38, 29 November 2024
  • Thumbnail for Rohon–Beard cell
    Furthermore, Rohon-Beard neurons did not show any signs of canonical programmed cell death. Neural crest Shimada N, Sokunbi G, Moorman SJ (May 2005). "Changes...
    9 KB (1,001 words) - 02:52, 10 February 2025
  • Thumbnail for Caspase
    Caspase (category Programmed cell death)
    in programmed cell death was first identified in 1993, with their functions in apoptosis well characterised. This is a form of programmed cell death, occurring...
    28 KB (3,134 words) - 05:08, 23 April 2025
  • Thumbnail for Autophagy
    mechanisms of programmed cell death (PCD) is associated with the appearance of autophagosomes and depends on autophagy proteins. This form of cell death most likely...
    79 KB (9,305 words) - 18:49, 4 May 2025
  • organism. These processes include cell proliferation, differentiation, cellular movement and programmed cell death. Each cell in an embryo receives molecular...
    25 KB (2,966 words) - 03:48, 13 May 2025
  • Thumbnail for Calliphora vomitoria
    tremendous amount of change for the fly, such as cell death. While it is commonly believed that programmed cell death and apoptosis are the same, they are not...
    26 KB (3,213 words) - 15:31, 5 October 2024
  • Thumbnail for Neurotrophin
    from initiating programmed cell death – allowing the neurons to survive. Neurotrophins also induce differentiation of progenitor cells, to form neurons...
    28 KB (3,081 words) - 19:11, 28 November 2024
  • and proteins and a loss of compartmentalization. Apoptosis, or programmed cell death, is generally characterized by distinct morphological characteristics...
    12 KB (1,397 words) - 09:59, 11 August 2024
  • Thumbnail for Ceramide
    examples include regulating differentiation, proliferation, and programmed cell death (PCD) of cells. The word ceramide comes from the Latin cera (wax) and amide...
    30 KB (3,370 words) - 15:04, 21 January 2025
  • Thumbnail for Neurodegenerative disease
    Apoptosis is a form of programmed cell death in multicellular organisms. It is one of the main types of programmed cell death (PCD) and involves a series...
    61 KB (6,888 words) - 19:02, 15 May 2025
  • Thumbnail for Pembrolizumab
    protective mechanism of cancer cells, allowing the immune system to destroy them. It targets the programmed cell death protein 1 (PD-1) receptor of lymphocytes...
    83 KB (7,695 words) - 22:22, 22 March 2025
  • Thumbnail for PD-1 and PD-L1 inhibitors
    association of the programmed death-ligand 1 (PD-L1) with its receptor, programmed cell death protein 1 (PD-1). The interaction of these cell surface proteins...
    35 KB (3,427 words) - 20:38, 5 February 2025
  • nasopharyngeal carcinoma. Toripalimab is a recombinant humanized programmed cell death protein 1 (PD-1) monoclonal antibody that acts as a checkpoint inhibitor...
    9 KB (640 words) - 21:57, 7 March 2025