c-Met inhibitors are a class of small molecules that inhibit the enzymatic activity of the c-Met tyrosine kinase, the receptor of hepatocyte growth factor/scatter...
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Hepatocyte growth factor receptor (redirect from Proto-oncogene proteins c-met)
of GRB2, phospholipase C γ (PLC-γ), p85, and SHP2. GAB1 is a key coordinator of the cellular responses to MET and binds the MET intracellular region with...
59 KB (6,731 words) - 19:27, 17 March 2025
muscular defects. Associated Genetic Factors: PAX3 and c-Met Mutations in PAX3 can cause a failure in c-Met expression. Such a mutation would result in a lack...
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proposed. c-MET may interact with FoxM1, a molecule important in the cell cycle, as FOXM1 levels decrease when c-MET is not present. Additionally, c-MET may...
92 KB (11,177 words) - 19:10, 5 May 2025
The Met Gala, formally called the Costume Institute Benefit, is the annual haute couture fundraising festival held for the benefit of the Metropolitan...
80 KB (6,430 words) - 03:40, 15 May 2025
The New York Mets are an American professional baseball team based in the New York City borough of Queens. The Mets compete in Major League Baseball (MLB)...
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of MetOp-A and MetOp-B, all three MetOp spacecraft were operated simultaneously until decommissioning of MetOp-A, MetOp-B and eventually MetOp-C. MetOp...
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hepatocyte growth factor (HGF) and potentiates its activity at its receptor, c-Met. The compound has been found to potently improve cognitive function in animal...
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tyrosine kinase signaling cascade after binding to the proto-oncogenic c-Met receptor. Hepatocyte growth factor is secreted by platelets, and mesenchymal...
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Centre for Development of Advanced Computing (C-DAC) Centre for Materials for Electronics Technology (C-MET) National Institute of Electronics and Information...
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How I Met Your Mother (often abbreviated as HIMYM) is an American sitcom created by Craig Thomas and Carter Bays for CBS. The series, which aired from...
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representatives of the two main Motherwell works teams Glencairn FC and Alpha F.C. met in Baillie's pub in the town's Merry Street, and decided to merge the two...
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Journal of Physics: Condensed Matter (redirect from J. Phys. F: Met. Phys.)
Milano-Bicocca). The journal was formed by the merger of Journal of Physics C: Solid State Physics and Journal of Physics F: Metal Physics in 1989. This...
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cell proliferation, it induces c-Met, a proto-oncogene that encodes the mesenchymal-epithelial transition factor (MET) protein. Increased invasiveness...
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Epithelioid sarcoma (section MET)
PMID 22701332. Kuhnen, C.; Tolnay, Edina; Steinau, Hans Ulrich; Voss, Bruno; Müller, Klaus-Michael (1998). "Expression of c-Met receptor and hepatocyte...
52 KB (5,913 words) - 23:27, 21 February 2025
Centre for Development of Advanced Computing (redirect from C-DAC)
computing C-DAC branches and training centres include: C-DAC Pune (Headquarters) C-DAC Mumbai C-DAC Bangalore C-DAC Chennai C-DAC Delhi C-DAC Kolkata C-DAC...
27 KB (2,077 words) - 14:34, 14 April 2025
December 23, 2024. "AJR's Adam Met earns PhD". 105.7 The Point. December 10, 2021. Retrieved December 23, 2024. Jones, C. T. (September 27, 2024). "This...
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The Met Office, until November 2000 officially the Meteorological Office, is the United Kingdom's national weather and climate service. It is an executive...
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(Baricitinib), and Iclusig (ponatinib). In 2013, Novartis acquired Incyte's c-Met inhibitor capmatinib (INC280, INCB028060), which is marketed under the brand...
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hepatocellular carcinoma. It is a small-molecule tyrosine-kinase inhibitor (TKI) of c-Met (HGFR) and VEGFR2, and also inhibits AXL, RET, and FLT3. It was discovered...
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Platelet-derived growth factor (redirect from Proto-oncogene proteins c-sis)
in this family include vascular endothelial growth factors B and C (VEGF-B, VEGF-C) which are active in angiogenesis and endothelial cell growth, and...
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kinase receptor, c-met, which is required for the survival and proliferation of migrating myoblasts during myogenesis. A lack of c-met disrupts secondary...
28 KB (3,078 words) - 17:48, 25 January 2025
an 80 in (2.0 m) plug at the rear of the fuselage. A single C-130K was purchased by the Met Office for use by its Meteorological Research Flight, where...
110 KB (12,413 words) - 22:53, 4 May 2025
The name of the club was changed to Leeds Met Carnegie during the early part of the 1990s. In 2004, Leeds Met left the Northern Universities League for...
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cancer. Vebreltinib selectively binds to c-Met, preventing its phosphorylation and thereby disrupting c-Met signal transduction pathways. In China, it...
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gathering force in those days. In 1897, when the First Provincial Conference met in Madras, he was invited to preside over it. The same year, when the Indian...
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treatment of non-small cell lung carcinoma (NSCLC). Crizotinib inhibits the c-Met/Hepatocyte growth factor receptor (HGFR) tyrosine kinase, which is involved...
22 KB (1,866 words) - 05:42, 2 November 2024
Tpr leucine zipper. The Tpr-Met fusion protein lacks the extracellular, transmembrane and juxtamembrane domains of c-Met receptor, and has gained the...
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small drug inhibitor of C-Met, as well a potential monoclonal antibody against hereditary gingival fibromatosis (HGF) and C-Met. Hydroxytyrosol Oleuropein...
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after the French city in which it was discovered. It is related to the c-MET receptor tyrosine kinase. MST1R has been shown to interact with Grb2. GRCh38:...
9 KB (1,088 words) - 22:17, 3 March 2023