• Thumbnail for 2-Imidazoline
    2-Imidazoline (Preferred IUPAC name: 4,5-dihydro-1H-imidazole) is one of three isomers of the nitrogen-containing heterocycle imidazoline, with the formula...
    10 KB (902 words) - 20:21, 28 August 2022
  • Thumbnail for Imidazoline
    3-imidazolines, and 4-imidazolines. The 2- and 3-imidazolines contain an imine center, whereas the 4-imidazolines contain an alkene group. The 2-Imidazoline...
    906 bytes (89 words) - 17:55, 5 May 2025
  • Imidazoline receptors are the primary receptors on which clonidine and other imidazolines act. There are three main classes of imidazoline receptor: I1...
    14 KB (1,312 words) - 18:27, 23 April 2025
  • Thumbnail for Rhinitis medicamentosa
    certain oral medications (e.g., sympathomimetic amines and various 2-imidazolines) that constrict blood vessels in the lining of the nose, although evidence...
    12 KB (1,166 words) - 12:09, 30 June 2024
  • attention. Lophine and its dihydro analogue amarine (meso-2,4,5-triphenyl-2-imidazoline) were discovered early in the history of organic chemistry (between...
    4 KB (267 words) - 00:12, 4 February 2025
  • Thumbnail for Imidazolidine
    intermediate, resulting from the addition of only two hydrogen atoms is called imidazoline (dihydroimidazole). The connection of imidazolidine to related compounds...
    5 KB (347 words) - 13:12, 17 May 2025
  • Thumbnail for Moxonidine
    Moxonidine (category Imidazoline receptor modulators)
    Moxonidine (INN) is a new-generation alpha-2/imidazoline receptor agonist antihypertensive drug licensed for the treatment of mild to moderate essential...
    10 KB (877 words) - 08:15, 28 March 2025
  • Thumbnail for Alpha-2 adrenergic receptor
    example of autoreceptor. However, it is now known that clonidine binds to imidazoline receptors with a much greater affinity than α2 receptors, which would...
    25 KB (2,218 words) - 04:02, 10 February 2025
  • Thumbnail for Lysidine (chemical)
    Lysidine (chemical) (category Imidazolines)
    Lysidine is a derivative of 2-imidazoline. It is a colorless solid with basic properties and soluble in organic solvents. It is used as a precursor to...
    3 KB (134 words) - 10:53, 13 December 2021
  • Thumbnail for Idazoxan
    Idazoxan (category Imidazoline antagonists)
    selective α2-adrenergic receptor antagonist, and an antagonist for the imidazoline receptor. Idazoxan has been under investigation as an antidepressant...
    7 KB (617 words) - 21:29, 21 February 2025
  • Thumbnail for Rhinitis
    use of certain oral medications (primarily sympathomimetic amine and 2-imidazoline derivatives) and topical decongestants (e.g., oxymetazoline, phenylephrine...
    34 KB (3,071 words) - 19:54, 25 December 2024
  • Thumbnail for Oxymetazoline
    Oxymetazoline (category Imidazolines)
    DE 1117588, Fruhstorfer W, Müller-Calgan H, "2-(2,6-dimethyl-3-hydroxy-4-tert-butyl-benzyl)-2-imidazoline,and acid addition salts thereof,and process for...
    16 KB (1,466 words) - 18:54, 29 March 2025
  • Thumbnail for Efaroxan
    Efaroxan (category Imidazoline receptor modulators)
    the imidazoline receptor. The Darzens reaction between 2-fluorobenzaldehyde [57848-46-1] (1) and Ethyl 2-bromobutyrate [533-68-6] (2) gives ethyl 2...
    4 KB (308 words) - 08:14, 28 March 2025
  • Thumbnail for 2-Imidazolidinethione
    Crystal Structures of Copper Complexes with 1-Methyl-1,3-imidazoline-2-thione and 1,3-Imidazoline-2-thione". Zeitschrift für Anorganische und Allgemeine Chemie...
    3 KB (164 words) - 20:08, 5 April 2024
  • Thumbnail for Nutlin
    Nutlin (redirect from Nutlin-2)
    Nutlins are cis-imidazoline analogs which inhibit the interaction between mdm2 and tumor suppressor p53, and which were discovered by screening a chemical...
    7 KB (603 words) - 01:53, 29 March 2025
  • Thumbnail for Mazindol
    Mazindol (category Imidazolines)
    3-diaminopropane. An alternative synthesis was described: 2-Phenyl-2-Imidazoline [936-49-2] (3) Methyl 4-Chlorobenzoate [1126-46-1] (4) As of 2016 mazindol...
    21 KB (1,700 words) - 01:35, 31 March 2025
  • Thumbnail for Clonidine
    Clonidine (redirect from Catapres-tts-2)
    RM (February 1999). "alpha-2 and imidazoline receptor agonists. Their pharmacology and therapeutic role". Anaesthesia. 54 (2): 146–165. doi:10.1046/j.1365-2044...
    61 KB (5,580 words) - 15:44, 4 May 2025
  • Thumbnail for Alpha-adrenergic agonist
    Selected examples are: Brimonidine Clonidine (mixed alpha2-adrenergic and imidazoline-I1 receptor agonist) Dexmedetomidine Fadolmidine Guanfacine, (preference...
    13 KB (1,316 words) - 23:48, 14 April 2025
  • Thumbnail for Tolonidine
    Tolonidine (category Imidazolines)
    Streichenberger, G. (1975). "Pharmacological properties of 2-(2-chloro-p-toluidino)-2-imidazoline-nitrate (Tolonidine), a new antihypertensive agent. I. Action...
    3 KB (156 words) - 07:47, 4 December 2023
  • Thumbnail for Oxazoline
    (2007). "Direct oxidative conversion of aldehydes and alcohols to 2-imidazolines and 2-oxazolines using molecular iodine". Tetrahedron. 63 (6): 1474–1480...
    17 KB (1,742 words) - 02:58, 5 November 2024
  • Prednazoline (category Imidazolines)
    4-diene-3,20-dione 21-(dihydrogen phosphate) compound with 2-[(2-isopropylphenoxy)methyl]-2-imidazoline Drug class Corticosteroid; Glucocorticoid Identifiers...
    3 KB (67 words) - 12:03, 28 January 2023
  • Thumbnail for CR-4056
    CR-4056 (category Imidazoline receptor modulators)
    candidate with a novel mechanism of action, acting as a ligand for the imidazoline receptor I2. It showed promising results in animal studies against various...
    4 KB (297 words) - 08:14, 28 March 2025
  • Thumbnail for Rilmenidine
    Rilmenidine (category Imidazoline receptor modulators)
    peripheral vasomotor structures. Rilmenidine is a imidazoline analog and shows greater selectivity for imidazoline receptors than for cerebral alpha2-adrenergic...
    8 KB (792 words) - 08:15, 28 March 2025
  • Thumbnail for Xylometazoline
    Xylometazoline (category Imidazolines)
    December 2016. US patent 2868802A, Hüni, Albrecht, "2-(γ-TERT-BUTYL-O,O'-DIMETHYL-PHENYL-METHYL)-IMIDAZOLINE AND SALTS", issued 13 January 1959, assigned to...
    14 KB (1,156 words) - 20:22, 24 March 2025
  • Thumbnail for Tetryzoline
    Tetryzoline (category Imidazolines)
    ingested the drug. There is no antidote for tetryzoline or other similar imidazoline analogue poisoning, but the symptoms can be alleviated. With treatment...
    14 KB (1,227 words) - 09:56, 6 January 2025
  • Agmatine (category Imidazoline agonists)
    targets: Neurotransmitter receptors and receptor ionophores. Nicotinic, imidazoline I1 and I2, α2-adrenergic, glutamate NMDAr, and serotonin 5-HT2A and 5HT-3...
    20 KB (2,105 words) - 15:05, 4 May 2025
  • Thumbnail for Heterocyclic compound
    Unsaturated (and partially unsaturated) 2 × Nitrogen Pyrazolidine Imidazolidine Pyrazole (Pyrazoline) Imidazole (Imidazoline) Nitrogen + Oxygen Oxazolidine Isoxazolidine...
    20 KB (1,062 words) - 22:54, 16 May 2025
  • may refer to: Aminopropionitrile (BAPN) Dihydroimidazol-2-ylidene Imidazolines 2-Imidazoline Pyrazoline This set index page lists chemical structure articles...
    333 bytes (62 words) - 01:53, 28 August 2022
  • Thumbnail for Clorgiline
    Clorgiline (category Imidazoline receptor modulators)
    with high affinity to the σ1 receptor (Ki = 3.2 nM) and with very high affinity to the I2 imidazoline receptor (Ki = 40 pM). Unlike selegiline, clorgiline...
    7 KB (550 words) - 08:15, 28 March 2025
  • Thumbnail for Imidazolidinone
    spiroxatrine. Imidazolones (also called imidazolinones) are oxo derivatives of imidazoline (dihydroimidazoles). Examples include imidazol-4-one-5-propionic acid...
    2 KB (226 words) - 01:45, 9 October 2023