The 43S preinitiation complex (43S PIC) is a ribonucleoprotein complex that exists during an early step of eukaryotic translation initiation. The 43S PIC...
6 KB (587 words) - 13:22, 22 July 2023
Eukaryotic translation (redirect from Translation preinitiation complex)
role in circularization of the mRNA during translation. This 43S preinitiation complex (43S PIC) accompanied by the protein factors moves along the mRNA...
16 KB (1,940 words) - 09:46, 9 March 2025
Met-tRNAiMet called the 43S preinitiation complex (43S PIC). Additional factors of the eIF4F complex (eIF4A, E, and G) recruit the 43S PIC to the five-prime...
13 KB (1,595 words) - 17:00, 27 August 2024
ternary complex (TC) with GTP and the initiator Met-tRNAiMet. After its formation, the TC binds the 40S ribosomal subunit to form the 43S preinitiation complex...
13 KB (1,538 words) - 08:39, 15 May 2025
Eukaryotic initiation factor 4F (category Protein complexes)
the formation of a single-stranded RNA landing pad for the 43S preinitiation complex (43S PIC) via eIF4A's RNA helicase activity. The eIF4F proteins interact...
7 KB (707 words) - 05:35, 18 January 2025
the 43S preinitiation complex (PIC). eIF1 and eIF1A bind cooperatively to the 40S to stabilize an "open" conformation of the preinitiation complex (PIC)...
7 KB (828 words) - 07:55, 8 March 2023
Eukaryotic initiation factor 3 (category Protein complexes)
and mRNA. eIF3 is a component of the multifactor complex (MFC) and 43S and 48S preinitiation complexes (PICs). The interactions of eIF3 with other initiation...
22 KB (2,101 words) - 01:49, 14 June 2024
A.; Frank, J. (2013). "Structure of the mammalian ribosomal 43S preinitiation complex bound to the scanning factor DHX29". Cell. 153 (5): 1108–1119...
40 KB (3,975 words) - 03:29, 17 May 2025
initiation factor 3 (eIF3) complex. The encoded protein is nearly identical to another protein, eIF3c, from a related gene. The eIF3 complex binds the 40S ribosome...
1 KB (168 words) - 16:41, 28 October 2022
interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter". EMBO Rep. 3 (11): 1082–7...
6 KB (826 words) - 23:13, 2 December 2023
Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170". J. Biol. Chem. 272 (2): 1110–6. doi:10.1074/jbc...
9 KB (1,134 words) - 01:51, 8 April 2022
Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170". J. Biol. Chem. 272 (2): 1110–6. doi:10.1074/jbc...
8 KB (1,078 words) - 16:41, 28 October 2022
of the subunits of Eukaryotic initiation factor 3 (eIF3) a multiprotein complex playing major roles in translation initiation in eukaryotes. EIF3A has...
12 KB (1,367 words) - 01:10, 29 March 2024
Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170". J. Biol. Chem. 272 (2): 1110–6. doi:10.1074/jbc...
7 KB (850 words) - 19:12, 13 August 2023
TV, Frank J (May 2013). "Structure of the mammalian ribosomal 43S preinitiation complex bound to the scanning factor DHX29". Cell. 153 (5): 1108–19. doi:10...
6 KB (693 words) - 09:41, 17 October 2022
subunit binding Cellular component cellular component eukaryotic 43S preinitiation complex Biological process translational initiation protein biosynthesis...
3 KB (372 words) - 22:08, 3 March 2023
complex cytosol eukaryotic translation initiation factor 3 complex, eIF3m eukaryotic 43S preinitiation complex eukaryotic 48S preinitiation complex Biological...
5 KB (597 words) - 00:26, 4 March 2023
the largest of the eIFs, is a multiprotein complex composed of at least ten nonidentical subunits. The complex binds to the 40S ribosome and helps maintain...
10 KB (1,093 words) - 10:29, 16 February 2025
(November 2005). "mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation...
8 KB (932 words) - 14:15, 13 October 2022
Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170". J. Biol. Chem. 272 (2): 1110–6. doi:10.1074/jbc...
5 KB (582 words) - 01:58, 4 March 2023
Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170". J. Biol. Chem. 272 (2): 1110–6. doi:10.1074/jbc...
8 KB (1,035 words) - 09:24, 18 August 2023
Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170". J. Biol. Chem. 272 (2): 1110–6. doi:10.1074/jbc...
8 KB (1,014 words) - 01:12, 29 March 2024
Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170". J. Biol. Chem. 272 (2): 1110–6. doi:10.1074/jbc...
9 KB (1,091 words) - 01:01, 9 April 2022
mRNA, a critical step necessary for the recruitment of the 43S preinitiation complex, and thus the translation of protein in eukaryotes. It was first...
24 KB (2,589 words) - 22:24, 6 October 2024
small protein (17 kDa in budding yeast) and a component of the 43S preinitiation complexes (PIC). eIF1A binds near the ribosomal A-site, in a manner similar...
8 KB (1,001 words) - 15:16, 31 July 2023
directly to the 40S ribosomal subunit and promoting formation of the 43S preinitiation complex. eIF3k has been shown to interact with Cyclin D3 and eIF3a. Eukaryotic...
5 KB (587 words) - 02:35, 17 April 2022
component of several translation initiation complexes, including the 43S and 48S preinitiation complexes (PICs), being bound by several eukaryotic initiation...
12 KB (1,044 words) - 17:55, 29 December 2023