Activity-based proteomics, or activity-based protein profiling (ABPP) is a functional proteomic technology that uses chemical probes that react with mechanistically...
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(ACS) Journal of Proteomics (Elsevier) Proteomics (Wiley) Biology portal Medicine portal Activity-based proteomics Bottom-up proteomics Cytomics Functional...
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Benjamin Cravatt III (redirect from Protomap (proteomics))
Institute in La Jolla, California. Considered a co-inventor of activity-based proteomics and a substantial contributor to research on the endocannabinoid...
7 KB (592 words) - 02:34, 29 May 2025
work to improve proteomics through the development of enrichment strategies, chemical affinity tags, and new probes. Samples for proteomics often contain...
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Activity-based proteomics Alpha/beta hydrolase fold Amide Enzyme Ester List of enzymes Thioester Simon GM, Cravatt BF (April 2010). "Activity-based proteomics...
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P7(CH3)3. Activity-based proteomics—A branch of biochemistry that often relies on organophosphorus probes to interrogate enzyme activities Bihar school...
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portal Activity-based proteomics – a branch of proteomics that uses covalent enzyme inhibitors as reporters to monitor enzyme activity. Antimetabolite – an...
104 KB (11,579 words) - 19:29, 18 September 2024
in the process of prokaryotic transcription. The basic unit of activity-based proteomics is the probe, which typically consists of two elements: a reactive...
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Degradomics (category Proteomics)
by Positional Proteomics. ACS Chem. Biol. 10, 1754-1764 (2015). Eckhard U., Marino G., Butler G. S., Overall C. M. Positional proteomics in the era of...
36 KB (5,012 words) - 20:38, 12 July 2024
Omics (section Proteomics)
emerging field of biological research at the intersection of proteomics and genomics. Proteomics data used for gene annotations. Structural genomics: Study...
26 KB (2,859 words) - 22:24, 23 May 2025
required to detect drug-protein interactions. Activity-based protein profiling (ABPP, also activity-based proteomics) is a technique that was developed to monitor...
63 KB (6,159 words) - 14:33, 30 November 2024
"Warhead", a component of agents used in Activity-based proteomics Cat's Cradle: Warhead, novel by Andrew Cartmel based on Doctor Who Crysis Warhead, a 2008...
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Protein (category Proteomics)
sets defines the field of proteomics, named by analogy to the related field of genomics. Key experimental techniques in proteomics include 2D electrophoresis...
105 KB (10,974 words) - 02:46, 10 July 2025
Biomarker discovery (category Proteomics)
Biomarker Biomarker (medicine) Clinical chemistry Clinical proteomics Drug discovery Genomics Proteomics Secretomics Endophenotype Massive parallel sequencing...
14 KB (1,667 words) - 16:46, 25 May 2025
SomaLogic (category Companies based in Boulder, Colorado)
companies, focusing on proteomic data. In 2019, SomaLogic entered into a new 10-year agreement with Novartis to use the SomaScan proteomics technology in drug...
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only based on a specific marker measured at a specific time point but also based on cells' kinetic behavior such as protein secretion, enzyme activity or...
212 KB (23,872 words) - 21:34, 16 June 2025
Single-cell analysis (section Proteomics)
subcellular analysis refer to the study of genomics, transcriptomics, proteomics, metabolomics, and cell–cell interactions at the level of an individual...
53 KB (6,347 words) - 03:23, 16 June 2025
Ancient protein (category Proteomics)
approaches: a digestion-free, top-down method and bottom-up proteomics. Top-down proteomics is seldom used to analyse ancient proteins due to analytical...
74 KB (7,980 words) - 14:07, 24 June 2025
Gene set enrichment analysis (category Proteomics)
enriched or depleted groups of genes. Transcriptomics technologies and proteomics results often identify thousands of genes, which are used for the analysis...
39 KB (4,629 words) - 12:14, 18 June 2025
glycosylase activity, whereas bifunctional glycosylases also possess AP lyase activity. Therefore, bifunctional glycosylases can convert a base lesion into...
29 KB (3,493 words) - 01:31, 15 January 2025
Oncology Laboratory at USC. He co-founded Applied Proteomics (API) with David Agus to make proteomics-based biomarker discovery practical. Hillis and his...
35 KB (2,879 words) - 02:33, 8 June 2025
using basic and acceptable platforms such as genomics and proteomics. Many genomic and proteomics techniques are available for biomarker discovery and a...
57 KB (7,099 words) - 03:55, 15 July 2025
Protein microarray (category Proteomics)
limitations of using DNA microarrays for determining gene expression levels in proteomics. The quantity of mRNA in the cell often doesn't reflect the expression...
23 KB (2,900 words) - 12:51, 23 June 2025
more recent times this research has been performed using LC-tandem MS based proteomics. The normal laboratory value of serum total protein is around 7 g/dL...
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Pathways to Drive Epithelial-Mesenchymal Transition". Molecular & Cellular Proteomics. 17 (10): 2005–2017. doi:10.1074/mcp.RA118.000882. PMC 6166677. PMID 29980616...
29 KB (3,485 words) - 06:51, 2 June 2025
Neurotransmission (redirect from Neuronal activity)
"Neuronal porosome proteome: Molecular dynamics and architecture". Journal of Proteomics. 75 (13): 3952–62. doi:10.1016/j.jprot.2012.05.017. PMC 4580231. PMID 22659300...
23 KB (2,721 words) - 22:21, 10 July 2025
Immunotherapy (redirect from Cell-based immunotherapy)
Huang TC, Hsu CL, Tsai SR, Lee SC, et al. (February 2015). "Quantitative proteomics reveals middle infrared radiation-interfered networks in breast cancer...
56 KB (6,106 words) - 00:34, 11 July 2025
Metaproteomics (also Community Proteomics, Environmental Proteomics, or Community Proteogenomics) is an umbrella term for experimental approaches to study...
19 KB (2,124 words) - 12:10, 28 May 2025
Petras, D.; Heiss, P.; Süssmuth, R. D.; Calvete, J. J. (2015). "Venom proteomics of Indonesian King Cobra, Ophiophagus hannah: Integrating top-down and...
54 KB (5,814 words) - 05:53, 12 July 2025
Drug design (redirect from Structure-based drug design)
and Proteomics. 1844 (11): 2002–2015. doi:10.1016/j.bbapap.2014.07.006. PMID 25110827. Tollenaere JP (April 1996). "The role of structure-based ligand...
44 KB (5,022 words) - 12:47, 20 April 2025