• Thumbnail for Alkylating antineoplastic agent
    An alkylating antineoplastic agent is an alkylating agent used in cancer treatment that attaches an alkyl group (CnH2n+1) to DNA. Since cancer cells, in...
    13 KB (1,449 words) - 09:45, 24 May 2025
  • Thumbnail for Alkylation
    Alkylation (redirect from Alkylating agent)
    of alkylating antineoplastic agents. Some chemical weapons such as mustard gas (sulfide of dichloroethyl) function as alkylating agents. Alkylated DNA...
    16 KB (1,686 words) - 21:12, 29 May 2025
  • Thumbnail for Chemotherapy
    treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) in a standard regimen. Chemotherapy may be given with a curative...
    155 KB (17,523 words) - 20:20, 29 May 2025
  • an alkylating antineoplastic agent of the oxazafosforine group; Carboplatin - a platinum-based antineoplastic drug, also an alkylating antineoplastic agent;...
    3 KB (183 words) - 17:16, 14 May 2024
  • (Gem)citabine - an antimetabolite; (Ox)aliplatin - a platinum-based alkylating antineoplastic agent. GEMOX-R regimen is a highly effective salvage regimen in patients...
    2 KB (124 words) - 18:54, 7 May 2021
  • antimetabolite; (P)latinol (cisplatin), a platinum-based antineoplastic, also an alkylating antineoplastic agent. Effective salvage therapy for lymphoma with cisplatin...
    2 KB (125 words) - 11:31, 25 July 2024
  • Platinum-based antineoplastic agents are sometimes described as "alkylating-like" due to similar effects as alkylating antineoplastic agents, although they...
    8 KB (830 words) - 06:37, 26 May 2025
  • Thumbnail for Busulfan
    Busulfan (category Alkylating antineoplastic agents)
    chemotherapy drug in use since 1959. It is a cell cycle non-specific alkylating antineoplastic agent, in the class of alkyl sulfonates. Its chemical designation...
    12 KB (1,224 words) - 08:29, 28 March 2025
  • cytarabine Platinol - Cisplatin, a platinum-based antineoplastic agent, also an alkylating antineoplastic agent. ESHAP--an effective chemotherapy regimen in...
    2 KB (105 words) - 18:59, 23 February 2024
  • an alkylating antineoplastic agent Etoposide- a topoisomerase inhibitor from the epipodophyllotoxin group Procarbazine - an alkylating antineoplastic agent...
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  • formation of microtubules and mitosis; Cyclophosphamide: an alkylating antineoplastic agent; Hydroxydaunorubicin, also known as doxorubicin: an anthracycline...
    6 KB (684 words) - 02:28, 25 May 2025
  • general formula R-SO2-O-R'. They act as alkylating agents, some of them are used as alkylating antineoplastic agents in the treatment of cancer, e.g. Busulfan...
    476 bytes (48 words) - 23:46, 17 March 2021
  • cells; Fludarabine - an antimetabolite; Cyclophosphamide - an alkylating antineoplastic agent from the oxazafosforine group; Mitoxantrone - a synthetic anthracycline...
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  • Thumbnail for Altretamine
    as an alkylating antineoplastic agent. This unique structure is believed to damage tumor cells through the production of the weakly alkylating species...
    7 KB (521 words) - 19:33, 31 August 2023
  • This is a list of antineoplastic agents used to treat cancer. Rossi, S, ed. (2013). Australian Medicines Handbook (2013 ed.). Adelaide: The Australian...
    52 KB (708 words) - 18:41, 16 January 2025
  • Thumbnail for Temozolomide
    Temozolomide (category Alkylating antineoplastic agents)
    warmth, swelling and redness, as well as bruising. Temozolomide is an alkylating agent used to treat serious brain cancers; most commonly as second-line treatments...
    32 KB (2,944 words) - 22:19, 29 May 2025
  • nonspecific antineoplastic agents (CCNS) refer to a class of pharmaceuticals that act as antitumor agents at all or any phases of the cell cycle. Alkylating antineoplastic...
    1 KB (116 words) - 20:19, 14 March 2025
  • Thumbnail for CYP2B6
    study of nevirapine in HIV-infected Cambodian patients". Antimicrobial Agents and Chemotherapy. 54 (10): 4432–4439. doi:10.1128/AAC.00512-10. PMC 2944557...
    20 KB (1,998 words) - 20:30, 29 May 2025
  • Duocarmycin (category Alkylating antineoplastic agents)
    groove binding alkylating agents, duocarmycins are suitable to target solid tumors. They bind to the minor groove of DNA and alkylate the nucleobase adenine...
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  • Thumbnail for Thiotepa
    Thiotepa (category Alkylating antineoplastic agents)
    metabolites accounts for 54 to 100% of the total alkylating activity, suggesting the existence of other alkylating metabolites. During the conversion of glutathione...
    41 KB (4,368 words) - 22:21, 29 May 2025
  • otherwise result from ifosfamide administration; Ifosfamide - an alkylating antineoplastic agent from oxazafosforine group; Mitoxantrone - a synthetic anthracycline...
    2 KB (147 words) - 16:45, 9 November 2021
  • Thumbnail for Treosulfan
    Treosulfan (category Alkylating antineoplastic agents)
    bone marrow transplant. It belongs to the family of drugs called alkylating agents. In the body, treosulfan is converted into other compounds called...
    15 KB (1,083 words) - 22:26, 29 May 2025
  • Thumbnail for Lomustine
    Lomustine (category Alkylating antineoplastic agents)
    treatment for cancers in cats and dogs. Lomustine is a bifunctional alkylating agent, alkylates both DNA and RNA, has the ability to created interstrand cross-links...
    26 KB (2,768 words) - 08:37, 17 April 2025
  • Thumbnail for Chlornaphazine
    Chlornaphazine (category Alkylating antineoplastic agents)
    since alkylating agents have their primary effect on rapidly proliferating cells which do not have time for DNA repair. The ability to alkylate DNA bases...
    26 KB (2,863 words) - 17:59, 22 May 2025
  • of alkyl groups to molecules, often by alkylating agents such as alkyl halides. Alkylating antineoplastic agents are a class of compounds that are used...
    12 KB (1,221 words) - 09:00, 24 May 2025
  • Ftortiazinon) – investigational antibiotic Fotretamine (Fotrin) – alkylating antineoplastic agent, immunosuppressant Gamofen (gamophen; amphetamine–GABA) – amphetamine...
    24 KB (1,940 words) - 05:10, 27 April 2025
  • Thumbnail for Ranimustine
    Ranimustine (category Alkylating antineoplastic agents)
    under the tradename Cymerin; also known as MCNU) is a nitrosourea alkylating agent approved in Japan for the treatment of chronic myelogenous leukemia...
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  • renal cell carcinoma and melanoma. List of hormonal cytostatic antineoplastic agents Antiestrogen withdrawal response Endocrine therapy resistance in...
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  • Thumbnail for Carcinogen
    agents is derived from studies of workers. Selected carcinogens Gasoline (contains aromatics) Lead and its compounds Alkylating antineoplastic agents...
    45 KB (4,590 words) - 17:10, 21 March 2025
  • Thumbnail for Chlorozotocin
    Chlorozotocin (category Alkylating antineoplastic agents)
    This antineoplastic or immunomodulatory drug article is a stub. You can help Wikipedia by expanding it....
    3 KB (75 words) - 22:35, 29 January 2023