Alpha-actinin-2 is a protein which in humans is encoded by the ACTN2 gene. This gene encodes an alpha-actinin isoform that is expressed in both skeletal...
21 KB (2,601 words) - 17:21, 3 December 2023
Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the...
13 KB (1,581 words) - 14:02, 19 January 2024
coordinates contractions between sarcomeres in the horizontal axis. Alpha-actinin is a part of the spectrin superfamily. This superfamily is made of spectrin...
13 KB (1,649 words) - 05:05, 3 June 2024
Alpha-actinin-1 is a protein that in humans is encoded by the ACTN1 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse...
12 KB (1,374 words) - 04:19, 8 March 2024
Alpha-actinin-4 is a protein that in humans is encoded by the ACTN4 gene. Alpha actinins belong to the spectrin gene superfamily which represents a diverse...
12 KB (1,455 words) - 04:22, 8 March 2024
intercalated discs. ALP functions to enhance the crosslinking of actin by alpha-actinin-2 and also appears to be essential for right ventricular chamber formation...
12 KB (1,442 words) - 01:33, 10 March 2024
TRPP3 is abundant in mouse brain where it associates with alpha-actinin-2. Alpha-actinin attaches TRPP3 to the cytoskeleton and up-regulates its channel...
11 KB (1,385 words) - 04:58, 3 September 2023
targeting and clustering of membrane proteins. ZASP interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its...
15 KB (1,591 words) - 05:43, 10 March 2024
muscle regeneration, to the muscle-specific actin-binding protein, alpha -actinin-2, is required for myoblast fusion". J. Biol. Chem. 275 (18): 13933–9...
13 KB (1,579 words) - 07:19, 29 April 2024
interact with DLG4, PDZ domain-containing proteins such as SAP97, and Actinin, alpha 2. Voltage-gated potassium channel GRCh38: Ensembl release 89: ENSG00000130037...
12 KB (1,460 words) - 21:07, 27 March 2024
disability with growth retardation. CAMK2A has been shown to interact with: Actinin alpha 4, CDK5R1, and DLG1. GRCh38: Ensembl release 89: ENSG00000070808 – Ensembl...
13 KB (1,466 words) - 02:09, 3 December 2023
gene. PDLIM1 has been shown to interact with: Actinin alpha 4, Actinin, alpha 1, Estrogen receptor alpha, and RNF12. GRCh38: Ensembl release 89: ENSG00000107438...
8 KB (1,069 words) - 11:40, 17 October 2022
myopodin interacts with stress fibers prior to co-localizing with alpha actinin-2 at Z-discs in mature striated muscle cells. Myopodin has been shown...
9 KB (1,055 words) - 23:25, 11 March 2024
Laboratory. Identified interaction partners include: CaMKII-alpha, alpha-Actinin and NR2B (via CaMKII-alpha), Cav1.3 (L-type Ca2+) channels, MAGUIN-1, Shank, PSD-95...
8 KB (1,106 words) - 20:34, 3 March 2023
that encode the same isoform. Zyxin has been shown to interact with: Actinin, alpha 1 ENAH, LASP1, LATS1, and Vasodilator-stimulated phosphoprotein. ENSG00000285443...
11 KB (1,262 words) - 19:59, 23 December 2023
composed of 496 amino acids. Myotilin was originally identified as a novel alpha-actinin binding partner with two Ig-like domains, that localized to the Z-disc...
17 KB (2,143 words) - 09:49, 10 March 2024
interaction between alpha-actinin and the beta 1 integrin subunit in vitro". The Journal of Cell Biology. 111 (2): 721–9. doi:10.1083/jcb.111.2.721. PMC 2116186...
22 KB (2,600 words) - 22:18, 2 April 2024
with proteins at the: Z-line, including telethonin (T-cap), alpha-actinin (ACTN), cofilin-2 (CFL2), calcineurin, HDAC4, MLP-b as well as to MLP itself;...
33 KB (4,114 words) - 00:22, 30 December 2023
List of A1 genes, proteins or receptors (redirect from Alpha 1 gene)
proteins or receptors named A1 or Alpha-1 : Actin, alpha 1 Actinin, alpha 1 Adaptor-related protein complex 2, alpha 1 Aldehyde dehydrogenase 3 family...
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muscle fibers. These electron-dense rod bodies are composed mainly of α-actinin and actin. The disorder is often clinically categorized into several groups...
51 KB (6,192 words) - 19:26, 10 May 2024
family protein, with alpha-actinin 2". J Cell Biochem. 78 (4): 558–65. doi:10.1002/1097-4644(20000915)78:4<558::AID-JCB5>3.0.CO;2-I. PMID 10861853. S2CID 84122657...
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muscle cells, pull-down experiments discovered ArgBP2 in complex with alpha actinin-2, vinculin, spectrin, paxillin, Pyk2 and flotillin, suggesting that...
17 KB (2,094 words) - 12:16, 4 January 2024
CDK5R2 (category Genes on human chromosome 2)
kinase-activating proteins. CDK5R2 has been shown to interact with Actinin, alpha 1. GRCh38: Ensembl release 89: ENSG00000171450 – Ensembl, May 2017 GRCm38:...
5 KB (632 words) - 20:58, 3 March 2023
and Kv1.4 potassium channels interacts with the spectrin repeats of alpha-actinin-2". FEBS Letters. 498 (1): 87–92. doi:10.1016/S0014-5793(01)02505-4....
14 KB (1,787 words) - 16:15, 14 May 2024
TRIM3 has been shown to interact with Actinin alpha 4. TRIM3 binds to and ubiquitinates Estrogen receptor alpha (ERa) leading to receptor's stabilization...
5 KB (678 words) - 01:22, 29 November 2023
Gene doping (section Alpha-actinin-3)
growth factor, fibroblast growth factor, endorphin, enkephalin and alpha-actinin-3. The risks of gene doping would be similar to those of gene therapy:...
32 KB (3,911 words) - 14:38, 6 June 2024
alpha-actinin at Z-discs, and inhibit the pathological cardiac hypertrophic response. This differs from the fast-skeletal muscle isoform, calsarcin-2...
10 KB (1,255 words) - 22:36, 3 March 2023
titin molecules are cross-linked in the Z-disc via the Z-line protein alpha-actinin. The M-band proteins myomesin as well as C-protein crosslink the thick...
12 KB (1,553 words) - 14:47, 30 May 2024
studies.[citation needed] Tight junction Pardo, JV, Craig, SW (1979). "alpha-Actinin localization in the junctional complex of intestinal epithelial cells"...
5 KB (505 words) - 05:55, 18 April 2024
Tang JX, Stafford WF, Chalovich JM (1999). "Calponin interaction with alpha-actinin-actin: evidence for a structural role for calponin". Biophysical Journal...
20 KB (2,182 words) - 02:03, 14 June 2023