• Thumbnail for Antigen presentation
    Antigen presentation is a vital immune process that is essential for T cell immune response triggering. Because T cells recognize only fragmented antigens...
    14 KB (1,670 words) - 00:44, 21 February 2025
  • Thumbnail for Antigen-presenting cell
    process is known as antigen presentation. T cells may recognize these complexes using their T cell receptors (TCRs). APCs process antigens and present them...
    16 KB (2,128 words) - 09:55, 4 March 2024
  • Antigen processing, or the cytosolic pathway, is an immunological process that prepares antigens for presentation to special cells of the immune system...
    12 KB (1,763 words) - 15:30, 15 April 2025
  • Thumbnail for Major histocompatibility complex
    molecules, which is to bind an antigen derived from self-proteins, or from pathogens, and bring the antigen presentation to the cell surface for recognition...
    58 KB (6,779 words) - 13:56, 9 May 2025
  • prior exposure to a specific antigen and contrasts the immune system's conventional role in eliminating foreign antigens. Depending on the site of induction...
    50 KB (6,091 words) - 17:55, 21 April 2025
  • "Human heat shock protein 70 enhances tumor antigen presentation through complex formation and intracellular antigen delivery without innate immune signaling"...
    49 KB (5,534 words) - 15:15, 2 May 2025
  • Thumbnail for Immune system
    recognition of specific "non-self" antigens during a process called antigen presentation. Antigen specificity allows for the generation of responses that are...
    119 KB (13,520 words) - 22:39, 15 April 2025
  • Thumbnail for Adaptive immune system
    Recognition of specific "non-self" antigens in the presence of "self", during the process of antigen presentation. Generation of responses that are tailored...
    57 KB (7,168 words) - 19:36, 31 March 2025
  • Thumbnail for MHC class II
    MHC class II (redirect from Hla-d antigens)
    histocompatibility complex (MHC) molecules normally found only on professional antigen-presenting cells such as dendritic cells, macrophages, some endothelial...
    17 KB (2,119 words) - 03:03, 6 March 2025
  • Thumbnail for Microglia
    derived, and express high levels of MHC class II proteins used for antigen presentation. This confirmed Pio Del Rio-Hortega's postulate that microglial cells...
    49 KB (5,772 words) - 13:30, 20 April 2025
  • Thumbnail for Polyclonal B cell response
    antigens) with its subsequent engulfing by B cells or macrophages. This activates the B cell only partially. Antigen processing. Antigen presentation...
    49 KB (5,613 words) - 10:01, 27 March 2024
  • Thumbnail for Phagocyte
    phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte moves parts of the ingested material...
    75 KB (8,286 words) - 15:15, 18 February 2025
  • Thumbnail for Major histocompatibility complex, class I-related
    isoform binds antigen via α1 and α2 interaction. Some bacteria are able to target specific β2 microglobulin that enable MHC I presentation. This might be...
    28 KB (3,218 words) - 23:38, 24 September 2024
  • proteasomal breakdown, as well as impairing antigen processing and MHC class I-restricted antigen presentation. This thereby inhibits the CD8-restricted...
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  • Thumbnail for B-cell receptor
    receptor transport, which eventually culminates in endocytosis and antigen presentation. B cells' mechanical activity adheres to a pattern of negative and...
    18 KB (2,180 words) - 06:36, 17 December 2024
  • nodes and spleen). Priming of naïve T cells requires dendritic cell antigen presentation. Priming of naive CD8 T cells generates cytotoxic T cells capable...
    10 KB (1,192 words) - 19:49, 9 February 2025
  • Thumbnail for DNA vaccine
    platform for monoclonal antibody induction. No risk for infections Antigen presentation by both MHC class I and class II molecules Polarise T-cell response...
    77 KB (8,378 words) - 02:14, 15 January 2025
  • Thumbnail for Immunoglobulin E
    "low-affinity" receptor FcεRII, or CD23. CD23 may also allow facilitated antigen presentation, an IgE-dependent mechanism whereby B cells expressing CD23 are able...
    28 KB (3,271 words) - 17:37, 31 March 2025
  • Thumbnail for Human leukocyte antigen
    The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation...
    51 KB (5,942 words) - 07:28, 11 November 2024
  • Cross-presentation is the ability of certain professional antigen-presenting cells (mostly dendritic cells) to take up, process and present extracellular...
    18 KB (2,159 words) - 21:24, 20 November 2024
  • Thumbnail for Phagosome
    those of macrophages and neutrophils, as DCs are mainly involved in antigen presentation rather than pathogen degradation. They need to retain protein fragments...
    28 KB (3,338 words) - 23:19, 13 May 2025
  • functions: phagocytosis and antigen presentation. Phagocytosis is the main process of macrophages and antigen presentation the main property of dendritic...
    6 KB (609 words) - 12:00, 10 August 2024
  • Thumbnail for CD74
    (Abbreviated Ii) is a polypeptide which plays a critical role in antigen presentation. It is involved in the formation and transport of MHC class II peptide...
    19 KB (2,221 words) - 23:09, 7 April 2025
  • Thumbnail for HLA-DM
    HLA-DM (human leukocyte antigen DM) is an intracellular protein involved in the mechanism of antigen presentation on antigen presenting cells (APCs) of...
    19 KB (2,371 words) - 10:20, 27 October 2024
  • Thumbnail for ERAP2
    different adenocarcinomas, has been suggested to modulate the presentation of cancer antigens on MHC-I, which may affect cancer invasion by immune cells...
    26 KB (2,669 words) - 00:15, 7 November 2024
  • Thumbnail for Innate immune system
    specialized white blood cells activate the adaptive immune system through antigen presentation act as a physical and chemical barrier to infectious agents; via...
    44 KB (4,847 words) - 15:03, 8 May 2025
  • Thumbnail for Monocyte
    intermediate subpopulation is important for antigen presentation and T lymphocyte stimulation. Briefly, antigen presentation describes a process during which microbial...
    31 KB (3,227 words) - 08:53, 30 April 2025
  • Thumbnail for MHC class I
    molecules. It is in this way, the MHC class I-dependent pathway of antigen presentation, that the virus infected cells signal T-cells that abnormal proteins...
    23 KB (2,917 words) - 07:11, 19 April 2025
  • Thumbnail for T helper cell
    (April 2015). "The ins and outs of MHC class II-mediated antigen processing and presentation". Nature Reviews. Immunology. 15 (4): 203–216. doi:10.1038/nri3818...
    54 KB (6,618 words) - 15:58, 30 April 2025
  • exhibit a gene expression signature characterised by down-regulating antigen presentation and B-cell receptor (BCR) function-related genes. Conversely, only...
    12 KB (1,254 words) - 04:30, 14 October 2024