Antigen presentation is a vital immune process that is essential for T cell immune response triggering. Because T cells recognize only fragmented antigens...
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process is known as antigen presentation. T cells may recognize these complexes using their T cell receptors (TCRs). APCs process antigens and present them...
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Antigen processing, or the cytosolic pathway, is an immunological process that prepares antigens for presentation to special cells of the immune system...
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Major histocompatibility complex (redirect from MHC antigen)
molecules, which is to bind an antigen derived from self-proteins, or from pathogens, and bring the antigen presentation to the cell surface for recognition...
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Immune tolerance (redirect from Self-antigen)
prior exposure to a specific antigen and contrasts the immune system's conventional role in eliminating foreign antigens. Depending on the site of induction...
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Heat shock protein (section Antigen presentation)
"Human heat shock protein 70 enhances tumor antigen presentation through complex formation and intracellular antigen delivery without innate immune signaling"...
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recognition of specific "non-self" antigens during a process called antigen presentation. Antigen specificity allows for the generation of responses that are...
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Adaptive immune system (section Antigen presentation)
Recognition of specific "non-self" antigens in the presence of "self", during the process of antigen presentation. Generation of responses that are tailored...
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MHC class II (redirect from Hla-d antigens)
histocompatibility complex (MHC) molecules normally found only on professional antigen-presenting cells such as dendritic cells, macrophages, some endothelial...
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Microglia (section Antigen presentation)
derived, and express high levels of MHC class II proteins used for antigen presentation. This confirmed Pio Del Rio-Hortega's postulate that microglial cells...
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antigens) with its subsequent engulfing by B cells or macrophages. This activates the B cell only partially. Antigen processing. Antigen presentation...
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Phagocyte (section Antigen presentation)
phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte moves parts of the ingested material...
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isoform binds antigen via α1 and α2 interaction. Some bacteria are able to target specific β2 microglobulin that enable MHC I presentation. This might be...
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proteasomal breakdown, as well as impairing antigen processing and MHC class I-restricted antigen presentation. This thereby inhibits the CD8-restricted...
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B-cell receptor (redirect from B-cell antigen receptor)
receptor transport, which eventually culminates in endocytosis and antigen presentation. B cells' mechanical activity adheres to a pattern of negative and...
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nodes and spleen). Priming of naïve T cells requires dendritic cell antigen presentation. Priming of naive CD8 T cells generates cytotoxic T cells capable...
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platform for monoclonal antibody induction. No risk for infections Antigen presentation by both MHC class I and class II molecules Polarise T-cell response...
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Immunoglobulin E (redirect from Reaginic antigen)
"low-affinity" receptor FcεRII, or CD23. CD23 may also allow facilitated antigen presentation, an IgE-dependent mechanism whereby B cells expressing CD23 are able...
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The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation...
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Cross-presentation is the ability of certain professional antigen-presenting cells (mostly dendritic cells) to take up, process and present extracellular...
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Phagosome (section Antigen presentation)
those of macrophages and neutrophils, as DCs are mainly involved in antigen presentation rather than pathogen degradation. They need to retain protein fragments...
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functions: phagocytosis and antigen presentation. Phagocytosis is the main process of macrophages and antigen presentation the main property of dendritic...
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(Abbreviated Ii) is a polypeptide which plays a critical role in antigen presentation. It is involved in the formation and transport of MHC class II peptide...
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HLA-DM (section Antigen loading and release)
HLA-DM (human leukocyte antigen DM) is an intracellular protein involved in the mechanism of antigen presentation on antigen presenting cells (APCs) of...
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ERAP2 (section Antigen presentation)
different adenocarcinomas, has been suggested to modulate the presentation of cancer antigens on MHC-I, which may affect cancer invasion by immune cells...
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specialized white blood cells activate the adaptive immune system through antigen presentation act as a physical and chemical barrier to infectious agents; via...
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intermediate subpopulation is important for antigen presentation and T lymphocyte stimulation. Briefly, antigen presentation describes a process during which microbial...
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MHC class I (redirect from Histocompatibility antigens class i)
molecules. It is in this way, the MHC class I-dependent pathway of antigen presentation, that the virus infected cells signal T-cells that abnormal proteins...
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(April 2015). "The ins and outs of MHC class II-mediated antigen processing and presentation". Nature Reviews. Immunology. 15 (4): 203–216. doi:10.1038/nri3818...
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exhibit a gene expression signature characterised by down-regulating antigen presentation and B-cell receptor (BCR) function-related genes. Conversely, only...
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