• The binding constant, or affinity constant/association constant, is a special case of the equilibrium constant K, and is the inverse of the dissociation...
    3 KB (369 words) - 22:42, 25 November 2024
  • Thumbnail for Ligand (biochemistry)
    dissociation constant (Kd) using methods such as fluorescence quenching, isothermal titration calorimetry or surface plasmon resonance. Low-affinity binding (high...
    29 KB (3,166 words) - 18:13, 27 April 2025
  • Cooperative binding occurs in molecular binding systems containing more than one type, or species, of molecule and in which one of the partners is not...
    39 KB (5,539 words) - 00:10, 13 December 2024
  • chemistry, filter binding assay is a method study the binding of macromolecules. It enables the determination of the binding constant, a number that describes...
    3 KB (484 words) - 16:17, 17 April 2025
  • Stability constants, formation constants, binding constants, association constants and dissociation constants are all types of equilibrium constants. For a...
    42 KB (6,736 words) - 13:46, 8 March 2025
  • an enzyme, the binding constant is also referred to as inhibition constant (KI). Molecules that can participate in molecular binding include proteins...
    12 KB (1,405 words) - 10:00, 27 March 2024
  • individual dissociation constant describes the equilibrium of ligands binding to specific binding sites. Because we assume identical binding sites with no cooperativity...
    20 KB (3,119 words) - 16:09, 18 December 2024
  • Thumbnail for Surface plasmon resonance
    dissociation rates ('off rate', kd), the equilibrium dissociation constant ('binding constant', KD) can be calculated. The detected SPR signal is a consequence...
    30 KB (3,654 words) - 12:43, 23 May 2025
  • coordination chemistry, a stability constant (also called formation constant or binding constant) is an equilibrium constant for the formation of a complex...
    60 KB (7,556 words) - 10:18, 14 May 2025
  • Thumbnail for Copper peptide GHK-Cu
    copper transport site on plasma albumin (albumin binding constant log 10 =16.2 vs. GHK binding constant 16 log 10 =16.44). It has been established that...
    20 KB (2,273 words) - 18:56, 3 May 2025
  • Quantitative analysis of binding constant values provides useful thermodynamic information.[citation needed] An association constant, K a ⊖ {\displaystyle...
    47 KB (7,173 words) - 07:24, 10 January 2025
  • is the equilibrium constant for the reaction of displacement by one ligand of another ligand in a complex with the substrate. Binding selectivity is of...
    15 KB (2,025 words) - 22:31, 2 May 2025
  • Thumbnail for Turing pattern
    the binding constants and diffusion rates of the BMP and Shh proteins. A small increase in the diffusion rate of BMP4 and a stronger binding constant of...
    19 KB (2,143 words) - 15:56, 25 April 2025
  • estimate these constants. The binding constant is a special case of the equilibrium constant K {\displaystyle K} . It is associated with the binding and unbinding...
    7 KB (1,127 words) - 08:58, 10 June 2024
  • Thumbnail for Isothermal titration calorimetry
    kinetic profile of the interaction by simultaneously determining binding constants ( K a {\displaystyle K_{a}} ), reaction stoichiometry ( n {\displaystyle...
    39 KB (4,577 words) - 13:58, 22 May 2025
  • “solutes that participate in a reaction in solution.” Binding constant Partition coefficient Binding affinity Schurr JM, Rangel DP, Aragon SR. (2005) "A...
    2 KB (211 words) - 03:04, 15 September 2024
  • Thumbnail for Protein–ligand complex
    given by the equilibrium dissociation constant Kd or the inverse of the association constant 1/Ka (or binding constant 1/Kb) that relates the concentrations...
    11 KB (1,297 words) - 07:08, 20 January 2024
  • Thumbnail for 18-Crown-6
    some metal cations with a particular affinity for potassium cations (binding constant in methanol: 106 M−1). The point group of 18-crown-6 is S6. The dipole...
    10 KB (990 words) - 22:29, 28 January 2025
  • maintaining the equilibrium constant of reactants throughout the assay, and the reliability and validity of linked reactions. Although binding assays are simple...
    33 KB (4,118 words) - 11:15, 25 May 2025
  • In physics and chemistry, binding energy is the smallest amount of energy required to remove a particle from a system of particles or to disassemble a...
    14 KB (1,342 words) - 13:09, 1 April 2025
  • Thumbnail for Fragment antigen-binding region
    The fragment antigen-binding region (Fab region) is a region on an antibody that binds to antigens. It is composed of one constant and one variable domain...
    6 KB (688 words) - 10:22, 9 September 2024
  • metabolites (structures and reactions), drug taxonomy, drug spectra, drug binding constants and drug synthesis information. Table 1 provides a more complete statistical...
    15 KB (998 words) - 01:15, 12 February 2025
  • such as stability constant, formation constant, binding constant, affinity constant, association constant and dissociation constant are used. In biochemistry...
    44 KB (6,725 words) - 10:14, 16 May 2025
  • Thumbnail for Gravitational binding energy
    The gravitational binding energy of a system is the minimum energy which must be added to it in order for the system to cease being in a gravitationally...
    10 KB (1,512 words) - 14:46, 17 May 2025
  • describes the strength of binding between a given protein and ligand. This relationship can be described by a dissociation constant, which characterizes the...
    16 KB (2,057 words) - 02:42, 27 October 2024
  • Thumbnail for Cetrimonium bromide
    = 0.2–0.1 (fractional charge; from low to high concentration). The binding constant (K°) of Br− counterion to a CTA+ micelle at 303 K (30 °C) is c. 400...
    21 KB (2,455 words) - 12:43, 10 February 2025
  • common binding techniques. However, the sensor's lifetime is limited by the stability of the enzyme. Antibodies have a high binding constant in excess...
    106 KB (12,175 words) - 22:51, 22 May 2025
  • non-covalently in order to maximize binding affinity binding constant and reduce the ability of the drug to dissociate from the binding site. This is achieved by...
    27 KB (3,311 words) - 09:42, 25 May 2025
  • Thumbnail for Adenosine triphosphate
    group, ATP binds metal cations with high affinity. The binding constant for Mg2+ is (9554). The binding of a divalent cation, almost always magnesium, strongly...
    52 KB (5,657 words) - 03:17, 19 May 2025
  • Thumbnail for Affinity electrophoresis
    to other molecules. The methods have been used for estimation of binding constants, as for instance in lectin affinity electrophoresis or characterization...
    19 KB (2,124 words) - 20:41, 22 May 2025