The C-terminus (also known as the carboxyl-terminus, carboxy-terminus, C-terminal tail, carboxy tail, C-terminal end, or COOH-terminus) is the end of an...
5 KB (583 words) - 18:03, 18 April 2024
the C-terminus, and a free amine group on the other end called the N-terminus. By convention, peptide sequences are written N-terminus to C-terminus, left...
7 KB (749 words) - 23:10, 30 March 2024
as the N-terminus or amino terminus, whereas the end of the protein with a free carboxyl group is known as the C-terminus or carboxy terminus (the sequence...
99 KB (11,210 words) - 04:06, 20 May 2024
which forms the N-terminus, and the carboxyl group, which forms the C-terminus; amino acid sequences are assembled in the N-to-C direction during translation...
272 KB (24,805 words) - 05:52, 18 May 2024
bond to the C-terminus, but entropically it was more favorable to hydrogen bond with the N-terminus. Specifically, they found that C-terminus hydrogen bonding...
22 KB (3,073 words) - 17:49, 30 December 2023
positioned such that their carboxyl-terminus is towards the cytosol, or Type II, which have their amino-terminus towards the cytosol. Type III proteins...
9 KB (1,035 words) - 19:59, 25 January 2024
(usually 16-30 amino acids long) present at the N-terminus (or occasionally nonclassically at the C-terminus or internally) of most newly synthesized proteins...
15 KB (1,741 words) - 18:05, 31 December 2023
found towards the C-terminus. The protein backbone is folded into five α-helices that are numbered α1-α5 from N-terminus to C-terminus. Helices α3, α4 and...
32 KB (3,790 words) - 12:18, 21 May 2024
consists of at least six histidine (His) residues, often at the N- or C-terminus of the protein. It is also known as a hexa histidine-tag, 6xHis-tag, or...
22 KB (2,639 words) - 16:13, 23 January 2024
Western blotting. The peptide sequence of the FLAG-tag from the N-terminus to the C-terminus is: DYKDDDDK (1012 Da). Additionally, FLAG-tags may be used in...
7 KB (846 words) - 23:15, 23 May 2024
extracellular N-terminus, cytoplasmic C-terminus, whereas ADIPORs are inverted). In terms of structure, GPCRs are characterized by an extracellular N-terminus, followed...
82 KB (9,384 words) - 23:27, 16 May 2024
covalently bound through its C-terminal carboxylate group to a particular lysine, cysteine, serine, threonine or N-terminus of the target protein. Polyubiquitylation...
98 KB (11,068 words) - 02:47, 20 February 2024
glycophosphatidylinositol (GPI) is a phosphoglyceride that can be attached to the C-terminus of a protein during posttranslational modification. The resulting GPI-anchored...
5 KB (642 words) - 19:59, 27 October 2023
used to modify biopolymers, fragment proteins and peptides (cuts the C-terminus of methionine), and synthesize other compounds. The compound is classified...
15 KB (1,502 words) - 04:29, 15 April 2024
C-terminus "polymerase relic" region, despite being unnecessary for polymerase activity, is thought to be essential to cell vitality. The C-terminus region...
59 KB (7,053 words) - 16:38, 28 April 2024
in the opposite order (starting at the C-terminus) to biological protein synthesis (starting at the N-terminus). Protein sequence is typically notated...
21 KB (2,595 words) - 18:06, 17 October 2023
helicase domain toward the C-terminus. Most parvoviruses contain a transcriptional activation domain near the C-terminus that upregulates transcription...
32 KB (4,019 words) - 20:08, 1 February 2024
linker between the cDNA and pIII at the C-terminus. pVIII is the main coat protein of Ff phages. Peptides are usually fused to the N-terminus of pVIII. Usually...
38 KB (4,622 words) - 00:46, 4 April 2024
threonine for solubility, and can either connect the N-terminus of the VH with the C-terminus of the VL, or vice versa. This protein retains the specificity...
11 KB (1,228 words) - 17:51, 29 July 2023
5′-to-3′ direction, and will extend the protein from its N-terminus toward its C-terminus. For example, in a typical gene a start codon (5′-ATG-3′) is...
9 KB (1,191 words) - 04:56, 25 December 2023
atomic mass and has 10 amino acids. It can be fused to the C-terminus and the N-terminus of a protein. It is advisable not to fuse the myc-tag directly...
2 KB (296 words) - 22:15, 4 April 2024
Because peptide chains have a directionality conferred by their N-terminus and C-terminus, β-strands too can be said to be directional. They are usually...
26 KB (3,100 words) - 18:37, 22 December 2023
histidines (H180 and H277). Association occurs between the C-terminus of RNR2 and the C-terminus of RNR1. Enzymatic activity is dependent on association...
34 KB (3,493 words) - 22:18, 19 May 2024
1, primarily located in the voltage sensitive S4 segment through the C-terminus. Of these mutations, 5 are nonsense mutations, 13 are missense mutations...
26 KB (2,574 words) - 21:37, 25 April 2024
trafficking cycle are believed to be encoded in the C-terminus. A dileucine motif in the C-terminus is required for VMAT2 endocytosis. Studies suggest...
43 KB (4,993 words) - 22:10, 12 March 2024
domain 2 (residues 118–174) is less basic and more hydrophobic and its C-terminus is at the end of p21; domain 3 (residues 175–191) is highly hydrophobic...
54 KB (6,585 words) - 09:53, 7 March 2024
starts at the carboxyl end of the peptide (C-terminus), and proceeds toward the amino-terminus (N-terminus). Protein biosynthesis (long peptides) in living...
50 KB (5,773 words) - 00:22, 20 February 2024
dnaC is a loading factor that complexes with the C-terminus of helicase dnaB and inhibits it from unwinding the dsDNA at a replication fork. A dnaB and...
2 KB (231 words) - 12:19, 5 February 2024
approximately 250 residues, from the N-terminus. Alpha-toxin has an additional 120 residues in the C-terminus. The C-terminus of the alpha-toxin has been reported...
25 KB (2,691 words) - 00:59, 17 April 2024