• A calcium channel opener is a type of drug which facilitates ion transmission through calcium channels. An example is Bay K8644, which is an analogue of...
    2 KB (283 words) - 03:57, 5 December 2020
  • include the following: Potassium channel openers Calcium channel openers Sodium channel openers Chloride channel openers This article includes a list of...
    447 bytes (80 words) - 16:48, 29 April 2024
  • A potassium channel opener is a type of drug which facilitates ion transmission through potassium channels. Some examples include: Diazoxide vasodilator...
    9 KB (831 words) - 06:28, 28 March 2024
  • Dihydropyridine calcium channel blockers are derivatives of 1,4-dihydropyridine that are used as L-type calcium channel blockers. They are used in the...
    13 KB (904 words) - 06:12, 21 January 2024
  • Chloride channel openers refer to a specific category of drugs designed to modulate chloride channels in the human body. Chloride channels are anion-selective...
    34 KB (4,495 words) - 03:20, 24 May 2024
  • Verrucotoxin (category Calcium channel openers)
    has been studied to interact with both calcium ion channels and potassium ATP channels. The calcium ion channel is modulated by the activation of the ꞵ-adrenoceptors...
    5 KB (601 words) - 03:38, 22 February 2024
  • Voltage-gated ion channels Calcium channel: see also Calcium channel blocker, Calcium channel opener Potassium channel: see also Potassium channel blocker, Potassium...
    3 KB (296 words) - 01:33, 5 October 2023
  • A sodium channel opener is a type of drug which facilitates ion transmission through sodium channels. Examples include toxins, such as aconitine, veratridine...
    1 KB (112 words) - 20:09, 12 May 2023
  • Thumbnail for Maitotoxin
    Maitotoxin (category Calcium channel openers)
    dinoflagellate Gambierdiscus toxicus. Maitotoxin activates extracellular calcium channels, leading to an increase in levels of cytosolic Ca2+ ions. The exact...
    19 KB (986 words) - 21:00, 6 January 2024
  • Thumbnail for Ion channel
    specific ion channels. These are classified by the channel on which they act: Calcium channel openers, such as Bay K8644 Chloride channel openers, such as...
    44 KB (5,155 words) - 07:00, 15 December 2023
  • Thumbnail for BK channel
    BK channels (big potassium), are large conductance calcium-activated potassium channels, also known as Maxi-K, slo1, or Kca1.1. BK channels are voltage-gated...
    32 KB (3,715 words) - 14:55, 1 March 2024
  • Thumbnail for NED-19
    endogenous calcium channel opener nicotinic acid adenine dinucleotide phosphate (NAADP), thereby reducing the normal NAADP-mediated calcium flux without...
    5 KB (438 words) - 23:56, 26 July 2023
  • phenytoin, oxcarbazepine (derivative of carbamazepine) Calcium has been shown to block sodium channels which explains the effects of hypercalcemia and hypocalcemia...
    11 KB (1,207 words) - 12:44, 8 November 2023
  • Thumbnail for Voltage-gated potassium channel
    arginines, are highly conserved in all voltage-gated potassium, sodium, or calcium channels. However, the extent of their movement and their displacement across...
    17 KB (1,770 words) - 14:20, 27 November 2023
  • Thumbnail for Calcium-activated potassium channel subunit alpha-1
    Calcium-activated potassium channel subunit alpha-1 also known as large conductance calcium-activated potassium channel, subfamily M, alpha member 1 (KCa1...
    20 KB (2,299 words) - 23:40, 2 December 2023
  • Thumbnail for Bay K8644
    Bay K8644 (category Calcium channel openers)
    Bay K8644 is a chemical compound that functions as an L-type calcium channel agonist. Bay K8644 is used primarily as a biochemical research tool for this...
    3 KB (132 words) - 08:54, 18 September 2021
  • Thumbnail for Calcium gluconate
    Calcium gluconate is the calcium salt of gluconic acid and is used as a mineral supplement and medication. As a medication it is used by injection into...
    18 KB (1,516 words) - 09:21, 22 May 2024
  • Thumbnail for SN-2
    SN-2 (category Calcium channel openers)
    chemical compound which acts as an "agonist" (i.e. channel opener) for the TRPML3 calcium channel, with high selectivity for TRPML3 and no significant...
    2 KB (140 words) - 11:26, 31 October 2023
  • Thumbnail for Isopimaric acid
    Isopimaric acid (category Potassium channel openers)
    a toxin which acts as a large conductance Ca2+-activated K+ channel (BK channel) opener. IPA originates from many sorts of trees, especially conifers...
    6 KB (416 words) - 23:51, 2 May 2023
  • Thumbnail for Ligand-gated ion channel
    Acid-sensing ion channel Calcium-activated potassium channel Cyclic nucleotide-gated ion channel Voltage-dependent calcium channel Receptor (biochemistry)...
    29 KB (2,597 words) - 03:43, 7 April 2024
  • Thumbnail for Nicorandil
    Nicorandil (category Potassium channel openers)
    arteries. L-type calcium channel expression increases in spastic vascular smooth muscle cells, which could result in excessive calcium influx, and hypercontraction...
    12 KB (1,087 words) - 20:00, 19 April 2024
  • Thumbnail for Potassium channel
    potassium channels. There are four major classes of potassium channels: Calcium-activated potassium channel - open in response to the presence of calcium ions...
    57 KB (5,815 words) - 05:21, 3 December 2023
  • Thumbnail for ML2-SA1
    ML2-SA1 (category Calcium channel openers)
    chemical compound which acts as an "agonist" (i.e. channel opener) for the TRPML2 calcium channel, with high selectivity for TRPML2 and no significant...
    2 KB (162 words) - 11:35, 31 October 2023
  • Thumbnail for MK6-83
    MK6-83 is a chemical compound which acts as a channel opener for the TRPML family of calcium channels, with moderate selectivity for TRPML1 over the related...
    2 KB (163 words) - 10:51, 11 December 2023
  • Thumbnail for Minoxidil
    Minoxidil (category Potassium channel openers)
    "elastase" enzyme activity in these tissues. In rats, potassium channel openers decrease calcium influx which inhibits elastin gene transcription through extracellular...
    48 KB (4,530 words) - 17:50, 27 April 2024
  • Thumbnail for ML-SA1
    "agonist" (i.e. channel opener) of the TRPML family of calcium channels. It has mainly been studied for its role in activating TRPML1 channels, although it...
    4 KB (339 words) - 17:45, 28 March 2024
  • channels close, causing the membrane potential of the cell to depolarize, activating voltage-gated calcium channels, and thus promoting the calcium-dependent...
    24 KB (2,575 words) - 18:07, 24 April 2024
  • Thumbnail for KCNN4
    KCNN4 (category Ion channels)
    Potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4, also known as KCNN4, is a human gene encoding the KCa3.1 protein...
    10 KB (1,297 words) - 14:02, 11 January 2023
  • Thumbnail for Rottlerin
    Rottlerin (category Potassium channel openers)
    post-ischemic changes in vasodilation. Other BKCa++ channel openers are reported to limit the mitochondrial calcium overload due to ischemia. Rottlerin is also...
    17 KB (1,665 words) - 23:42, 20 September 2023
  • Thumbnail for Diazoxide
    Diazoxide (category Potassium channel openers)
    cells of the pancreas. Opening these channels leads to hyperpolarization of cell membrane, a decrease in calcium influx, and a subsequently reduced release...
    11 KB (892 words) - 04:28, 28 May 2024