Calcium modulating ligand (CAMLG or CAML), also known as calcium-modulating cyclophilin ligand, is a signalling protein recognized by the TNF receptor...

dialect of the ML programming language. CAML may also refer to: Calcium modulating ligand Canadian Association of Music Libraries, Archives and Documentation...

bind (i.e., an orthosteric site). Modulators and agonists can both be called receptor ligands. Allosteric modulators can be 1 of 3 types either: positive...

Ligand-gated ion channels (LICs, LGIC), also commonly referred to as ionotropic receptors, are a group of transmembrane ion-channel proteins which open...

to a depolarization or increase in calcium levels. Structurally, BK channels are homologous to voltage- and ligand-gated potassium channels, having a...

The calcium-sensing receptor (CaSR) is a Class C G-protein coupled receptor which senses extracellular levels of calcium ions. It is primarily expressed...

Calcium channel blockers (CCB), calcium channel antagonists or calcium antagonists are a group of medications that disrupt the movement of calcium (Ca2+)...

response to the binding of a ligand to it. Leak sodium channels additionally contribute to action potential regulation by modulating the resting potential (and...

site or the binding site of the endogenous ligand of a receptor are called orthosteric regulators or modulators. The site to which the effector binds is...

that combines a recombinant transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) and a fragment of human immunoglobulin...

sends the signal onward, amplification increases the effect of a single ligand, and integration allows the signal to be incorporated into another biochemical...

subtypes, is a chaperone protein at the endoplasmic reticulum (ER) that modulates calcium signaling through the IP3 receptor. In humans, the σ1 receptor is...

separate dative covalent bonds between a ligand and a single metal atom, thereby forming a ring structure. The ligand is called a chelant, chelator, chelating...

different neuropeptides and hormones. ADRB-1 receptors can play a role in modulating the release of neuropeptides like vasoactive intestinal peptide (VIP)...

The 5-HT3 receptor belongs to the Cys-loop superfamily of ligand-gated ion channels (LGICs) and therefore differs structurally and functionally from all...

calcium channel (also known as the dihydropyridine channel, or DHP channel) is part of the high-voltage activated family of voltage-dependent calcium...

functions such as modulating the actions of excitatory and inhibitory ion channels or triggering a signalling cascade that releases calcium from stores inside...

capable of being shut off by chemical ligands even though they do not require ligands in order to operate. Ligand-gated ion channels are channels whose...

voltage-gated and ligand-gated channels, which can be directly affected by cannabinoids. More specifically, cannabinoids reduce calcium influx by blocking...

target for the development of channel modulating drugs such as chloride channel openers. Chloride channel modulators include chloride channel openers, and...

Calcium-activated potassium channels are potassium channels gated by calcium, or that are structurally or phylogenetically related to calcium gated channels...

pharmacological techniques have been used to adjust SK affinity for calcium ions, thereby modulating the excitability of substantia nigra dopaminergic neurons....

activated by low intracellular calcium levels and inhibited by high intracellular calcium levels. In response to calcium levels, guanylate cyclase synthesizes...

are still considered voltage-dependent channels. Calcium, calmodulin, and phosphorylation modulate the opening of CNG channels. The main role of CNG...

the increase in cytosolic calcium cations leads to synthesis of prostaglandins. Activation of TRPV1 by capsaicin modulates neutrophil immune response...

more potent than IP3. IP3R is a ligand-gated intracellular Ca2+ release channel that plays a central role in modulating cytoplasmic free Ca2+ concentration...

spiders, scorpions, snakes, fish, bees, sea snails, and others) work by modulating ion channel conductance and/or kinetics. In addition, ion channels are...

mechanisms remains an area of research, but ethanol has been shown to affect ligand-gated ion channels, particularly the GABAA receptor. After oral ingestion...

Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic...

Examples of targets for modulators include: Voltage-gated ion channels Calcium channel: see also Calcium channel blocker, Calcium channel opener Potassium...