Cancer procoagulant is a hypothesised protein, most likely a cysteine protease enzyme (EC 3.4.22.26), that occurs only in fetal and malignant cells. Its...
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Coagulation (redirect from Procoagulant)
8 September 2023. Gordon, S. G.; Mielicki, W. P. (March 1997). "Cancer procoagulant: a factor X activator, tumor marker and growth factor from malignant...
64 KB (6,646 words) - 14:53, 11 May 2025
24: Cathepsin T EC 3.4.22.25: Glycyl endopeptidase EC 3.4.22.26: Cancer procoagulant EC 3.4.22.27: cathepsin S EC 3.4.22.28: picornain 3C EC 3.4.22.29:...
119 KB (15,563 words) - 19:44, 6 May 2025
Platelet-mimicking particle (section Cancer)
one study, researchers evaluated the efficacy of platelet-mimicking procoagulant nanoparticles (PPNs) using various animal models. In a mouse model of...
42 KB (4,822 words) - 16:42, 1 June 2025
damaged erythrocytes have a procoagulant activity then the substances they release can lead to the development of a procoagulant state and this can cause...
16 KB (1,838 words) - 21:50, 13 May 2025
coagulation by converting thrombin to an anticoagulant enzyme from a procoagulant enzyme. Thrombomodulin is also expressed on human mesothelial cell, monocyte...
13 KB (1,470 words) - 04:21, 15 October 2024
could be speculated that some of the benefit might be secondary to the procoagulant effect of erythropoietin. Regardless, this study suggests further research...
25 KB (2,325 words) - 20:45, 29 May 2025
and colon cancer patients (other forms of cancer also can be factors, but these are the most common) This is due to the release of procoagulants. The risk...
87 KB (9,772 words) - 19:04, 22 May 2025
Duffy antigen system (section Cancer)
status, both lymph node and distant metastasis and poor survival. The procoagulant response to lipopolysaccharide (bacterial endotoxin) is reduced in Duffy...
75 KB (9,577 words) - 05:53, 2 June 2025
Estrogen (medication) (section Hormonal cancer)
estrogen. Due to its effects on liver protein synthesis, oral estrogen is procoagulant, and has been found to increase the risk of venous thromboembolism (VTE)...
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hypertension. This category is ruled by surface phenomena and contact with procoagulant surfaces, such as bacteria, shards of foreign materials, biomaterials...
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century. Ultracentrifuged pellets from blood plasma were reported to have procoagulant properties by Erwin Chargaff and Randolph West in 1946. The platelet...
63 KB (6,975 words) - 18:49, 28 May 2025
activation of the coagulation system by cancer cells or secretion of procoagulant substances (paraneoplastic syndrome), by external compression on a blood...
48 KB (4,720 words) - 03:40, 2 June 2025
the thrombin receptor in blood vessel walls, which may contribute to procoagulant effects of MPA and risk of venous thromboembolism and atherosclerosis...
182 KB (19,047 words) - 21:27, 29 May 2025
initiated by interaction of S100A8/A9 with GPIbα induces the formation of procoagulant platelets and fibrin (CD36 has a supporting role). Transition metals...
22 KB (2,176 words) - 20:22, 24 August 2024
Horvat (December 2013). "Interferons beta have vasoconstrictive and procoagulant effects: a woman who developed livedo reticularis and Raynaud phenomenon...
25 KB (2,544 words) - 12:17, 2 December 2024
Australia. Its venom contains powerful neurotoxins, nephrotoxins and a procoagulant, although humans are not usually affected by the neurotoxins. The bite...
145 KB (17,145 words) - 03:42, 31 May 2025
activation of the coagulation system by cancer cells or secretion of procoagulant substances. Furthermore, particular cancer treatments (such as the use of central...
47 KB (5,588 words) - 18:49, 22 May 2025
intracardiac thrombi have been embolised peripherally. In certain patients, procoagulant therapy may result in thrombosis of the intracranial veins (lateral sinus...
26 KB (2,491 words) - 20:07, 10 September 2024
associated with a doubled risk for silent stroke. Cigarette smoking: The procoagulant and atherogenic effects of smoking increase the risk for silent stroke...
35 KB (4,015 words) - 04:42, 29 September 2024
the endothelium of human blood vessels and catalyze the conversion of procoagulant clotting factors into activated ones, leading to unwanted and potentially...
69 KB (7,737 words) - 21:20, 4 June 2025
necessarily mean the patient has a tendency to bleed, as it only measures procoagulants and not anticoagulants. In liver disease the synthesis of both are decreased...
25 KB (2,908 words) - 11:16, 25 May 2025
killing the bacteria directly. Platelets also secrete proinflammatory and procoagulant mediators such as inorganic polyphosphates or platelet factor 4 (PF4)...
71 KB (8,530 words) - 16:53, 8 May 2025
warfarin metabolism). Warfarin is an anticoagulant that opposes the procoagulant effect of vitamin K by inhibiting the VKORC enzyme. A patient's VKORC1...
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instead, it prevents clot formation by inhibiting thrombin and other procoagulant serine proteases. Heparin is generally used for anticoagulation for the...
78 KB (7,850 words) - 21:03, 29 May 2025
K, et al. (August 2010). "Early atherosclerosis exhibits an enhanced procoagulant state". Circulation. 122 (8): 821–830. doi:10.1161/CIRCULATIONAHA.109...
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via rapamycin and the rapalogs. Rapamycin and its analogues also have procoagulant side effects caused by off-target binding of the activated immunophilin...
69 KB (7,807 words) - 19:19, 19 September 2024
involved. The binding of XNAs ultimately leads to the development of a procoagulant state, the secretion of inflammatory cytokines and chemokines, as well...
73 KB (8,536 words) - 22:35, 29 May 2025
estradiol cypionate and 25 mg medroxyprogesterone acetate have less or no procoagulant effect relative to combined birth control pills. In contrast to oral...
51 KB (5,073 words) - 20:46, 29 May 2025
Cohen, Zane; Craig, Monica; et al. (March 1989). "Monocyte/macrophage procoagulant activity as a measure of immune responsiveness in Lewis and brown Norway...
124 KB (11,901 words) - 15:50, 21 May 2025