The 5' cap of eukaryotic messenger RNA is bound at all times by various cap-binding complexes (CBCs). In the nucleus, freshly transcribed mRNA molecules...

Nuclear cap-binding protein complex is a RNA-binding protein which binds to the 5' cap of pre-mRNA. The cap and nuclear cap-binding protein have many...

by the cap binding complex (CBC), which binds exclusively to 7-methylguanylate-capped RNA. The CBC is then recognized by the nuclear pore complex and exported...

through the nuclear pore by binding to the cap-binding proteins CBP20 and CBP80, as well as the transcription/export complex (TREX). Multiple mRNA export...

eukaryotic translation initiation and is a component of the eIF4F cap-binding complex. Orthologs of eIF4G have been studied in multiple species, including...

Cannabichromene, a non-psychoactive cannabinoid found in cannabis Cap binding complex, a protein complex Cipher block chaining, a block cipher mode of operation...

the binding site of the cap-synthesizing and cap-binding complex. In eukaryotes, after transcription of the 5' end of an RNA transcript, the cap-synthesizing...

protect the RNA from degradation by exonucleases. The m7G cap is then bound by cap binding complex heterodimer (CBP20/CBP80), which aids in mRNA export to...

The human TREX complex is recruited to a region near the 5' end of mRNA by interaction of ALY and THO with the nuclear cap-binding complex. As a chaperone...

components. eIF4E is the cap-binding protein. Binding of the cap by eIF4E is often considered the rate-limiting step of cap-dependent initiation, and...

M. A., Claggett, J. M., Nguyen, T., & Johnson, T. L. (2009). The cap binding complex influences H2B ubiquitination by facilitating splicing of the SUS1...

DEAD-box RNA helicase eIF4A, the cap-binding protein eIF4E, and the large "scaffold" protein eIF4G. The mammalian eIF4F complex was first described in 1983...

directly binding to the SOX2 promoter and positively regulating its transcription. It enables the binding activity of the mRNA cap binding complex and the...

complex and assists the TREX complex in the nuclear export process. NCBP1 and NCBP3 are both part of the cap-binding complex. The two proteins interact...

cap-binding proteins such as eIF3D, eIF3I, PARN, and the nuclear cap-binding complex (CBC) can mediate specialized translation pathways. In addition to...

the DNA. Each subunit of CAP is composed of a ligand-binding domain at the N-terminus (CAPN, residues 1–138) and a DNA-binding domain at the C-terminus...

regulator of translation. FMRP is an RNA-binding protein which associates with polyribosomes. The RNA-binding abilities of FMRP are dependent upon its...

might contribute to repression via the 5' cap. preventing the binding of the 60S ribosomal subunit binding to the mRNA can repress translation. Translation...

Single-strand binding protein Telomere-binding protein RNA-binding protein Poly(A)-binding protein Nuclear cap-binding protein complex CREB-binding protein...

Poly(A)-binding protein (PAB or PABP) is an RNA-binding protein which triggers the binding of eukaryotic initiation factor 4 complex (eIF4G) directly to...

naturally inhibit the binding of two initiation factors necessary for interaction of transcribed mRNA with the subunits of ribosomal complexes. These naturally...

R, Chico L, Mao N, Steinberg-Neifach O, Ha T (2013). "The telomere capping complex CST has an unusual stoichiometry, makes multipartite interaction with...

initiation factor 4E-binding protein 1 (also known as 4E-BP1) is a protein that in humans is encoded by the EIF4EBP1 gene. It inhibits cap-dependent translation...

salary cap to control costs and benefit parity, defined by the league's collective bargaining agreement (CBA). This limit is subject to a complex system...

absent, high level of CAP protein/cAMP complex bind to CAP binding site, a site between araI1 and araO1. Binding of CAP/cAMP is responsible for opening up...

PMID 17236129. Wilson KF, Fortes P, Singh US, et al. (1999). "The nuclear cap-binding complex is a novel target of growth factor receptor-coupled signal transduction"...

disassociation of nuclear mRNA binding proteins and replacement with cytoplasmic mRNA binding proteins. Cap binding complex dependent translation initiation...

ubiquitin binding protein within the ESCRT-0 complex. Localization in the Cell (In Vivo): Both Hrs and STAM are found on endosomal membranes. Complex Formation:...

WAVE regulatory complex (WRC), and based on the crystal structure of the WRC it is believed CYFIP1 provides the binding site for the complex to Rac1. ENSG00000273749...

methylated guanosine (m7G) cap is added to RNA by a capping complex that associates with RNA polymerase II (RNAP II), the NAD cap is added during transcriptional...