Unlike the action potential in skeletal muscle cells, the cardiac action potential is not initiated by nervous activity. Instead, it arises from a group...

action potentials, such as the cardiac action potential and the action potential in the single-cell alga Acetabularia, respectively. Although action potentials...

Lakatta, Edward G. (2015). "Potential effects of intrinsic heart pacemaker cell mechanisms on dysrhythmic cardiac action potential firing". Frontiers in Physiology...

membrane potentials. As the membrane voltage begins to drop the channels recover from inactivation and carry current. Cardiac action potential Grant, Augustus...

upstroke of the cardiac action potential there is a large influx of Na+ ions. This depolarizes the cell and shifts the membrane potential in the positive...

cardiomyocytes known as pacemaker cells that can spontaneously generate cardiac action potentials. These signals are propagated through the heart's electrical conduction...

repolarization peak. Cardiac action potential Vigmond E.J, Tsoi V, Yin Y, Page P, & Vinet A. (2009). Estimating Atrial Action Potential Duration from Electrograms...

vena cava. These cells produce an electrical impulse known as a cardiac action potential that travels through the electrical conduction system of the heart...

important differences. Electrical stimulation in the form of a cardiac action potential triggers the release of calcium from the cell's internal calcium...

multiple modes of action, which makes any classification imprecise. The cardiac myocyte has two general types of action potentials: conduction system...

systole). Apex beat Cardiac action potential Cardiac output Pulse Pollock JD, Makaryus AN (3 October 2022). "Physiology: Cardiac cycle". StatPearls Publishing...

the entry of sodium in heart cells, causing prolongation of the cardiac action potential. Flecainide was approved for medical use in the United States in...

current. Pacemaker action potential Graded potential Wei, Xingyu; Yohannan, Sandesh; Richards, John R. (2025). "Physiology, Cardiac Repolarization Dispersion...

the hERG channel mediates the repolarizing IKr current in the cardiac action potential, which helps coordinate the heart's beating. When this channel's...

phase of the cardiac action potential. As such, it plays a major role in impulse propagation through the heart. A vast number of cardiac diseases is associated...

each ventricular systole. Cardiac muscle tissue has autorhythmicity, the unique ability to initiate a cardiac action potential at a fixed rate – spreading...

antiarrhythmics. MSA agents produced by beta-blockers reduce the increase of cardiac action potential, while also leading to other electrophysiological effects. However...

an action potential. The cardiac action potential is created by the movement of specific electrolytes into and out of the pacemaker cells. The action potential...

contributes to the repolarization of the cell, terminating the cardiac action potential and thereby the heart's contraction. It is a member of the KCNQ...

cardiomyocytes with fewer myofibrils and many mitochondria. They conduct cardiac action potentials more quickly and efficiently than any of the other cells in the...

steady heartbeat. At the beginning of the cardiac cycle, the SA node generates an electrical action potential that spreads across the right and left atria...

abnormal depolarizations of cardiac myocytes that interrupt phase 2, phase 3, or phase 4 of the cardiac action potential in the electrical conduction...

caused by mutations in genes encoding ion channels that shorten the cardiac action potential, and appears to be inherited in an autosomal dominant pattern....

change in voltage is referred to as an action potential. Unlike that in nerve cells, the cardiac action potential duration is closer to 100 ms (with variations...

propagates through cardiac muscle very rapidly. Cells of the ventricles contract nearly simultaneously. The action potentials of cardiac muscle are unusually...

specifically the potassium currents Ito and IKs that repolarise the cardiac action potential. Under certain circumstances, this can lead to prolongation of...

grouped by their effect on the Na+ channel, and by their effect on cardiac action potentials. Class I agents are called Membrane Stabilizing Agents. 'Stabilizing'...

involved in cardiac repolarization during phase 3 of the action potential, so that this blockade prolongs the duration of cardiac action potentials, resulting...

sustained contractions because it forces the refractory period and cardiac action potential firing to be of the same length of time. Repolarization depends...

cardiac calcium channels. An increased calcium influx from the sarcoplasmic reticulum (SR) during phase 2 (the plateau phase) of the cardiac action potential...