organic chemistry, a coupling reaction is a type of reaction in which two reactant molecules are bonded together. Such reactions often require the aid...

cross-coupling reaction is a reaction where two different fragments are joined. Cross-couplings are a subset of the more general coupling reactions. Often...

The Suzuki reaction or Suzuki coupling is an organic reaction that uses a palladium complex catalyst to cross-couple a boronic acid to an organohalide...

The Negishi coupling is a widely employed transition metal catalyzed cross-coupling reaction. The reaction couples organic halides or triflates with organozinc...

The Sonogashira reaction is a cross-coupling reaction used in organic synthesis to form carbon–carbon bonds. It employs a palladium catalyst as well as...

The A3 coupling (also known as A3 coupling reaction or the aldehyde-alkyne-amine reaction), coined by Prof. Chao-Jun Li of McGill University, is a type...

Buchwald–Hartwig amination is a chemical reaction for the synthesis of carbon–nitrogen bonds via the palladium-catalyzed coupling reactions of amines with aryl halides...

In organic chemistry, an azo coupling is an reaction between a diazonium compound (R−N≡N+) and another aromatic compound that produces an azo compound...

A pinacol coupling reaction is an organic reaction in which a carbon–carbon bond is formed between the carbonyl groups of an aldehyde or a ketone in presence...

Decarboxylative cross coupling reactions are chemical reactions in which a carboxylic acid is reacted with an organic halide to form a new carbon-carbon...

cross-coupling reactions. The Heck reaction is a way to substitute alkenes. The original reaction by Tsutomu Mizoroki (1971) describes the coupling between...

The Hiyama coupling is a palladium-catalyzed cross-coupling reaction of organosilanes with organic halides used in organic chemistry to form carbon–carbon...

The Stille reaction is a chemical reaction widely used in organic synthesis. The reaction involves the coupling of two organic groups, one of which is...

Oxidative coupling of phenols is a chemical reaction wherein two phenolic compounds are coupled via an oxidative process. Oxidative phenol couplings are often...

creating useful coupling partners. This group transfer reaction can be used in allylation, or other coupling reactions (such as Negishi coupling). One of the...

The Glaser coupling is a type of coupling reaction. It is by far one of the oldest coupling reactions and is based on copper compounds like copper(I) chloride...

In organic chemistry, the Wurtz reaction, named after Charles Adolphe Wurtz, is a coupling reaction in which two alkyl halides are treated with sodium...

chemistry, the Kumada coupling is a type of cross coupling reaction, useful for generating carbon–carbon bonds by the reaction of a Grignard reagent and...

reactions are examples of cross-coupling reactions. Ullmann-type reactions are comparable to Buchwald–Hartwig reactions but usually require higher temperatures...

The Ullmann reaction or Ullmann coupling, named after Fritz Ullmann, couples two aryl or alkyl groups with the help of copper. The reaction was first reported...

The Chan–Lam coupling reaction, also known as the Chan–Evans–Lam coupling, is a cross-coupling reaction between an aryl boronic acid and an alcohol or...

The Wittig reaction or Wittig olefination is a chemical reaction of an aldehyde or ketone with a triphenyl phosphonium ylide called a Wittig reagent....

N-tosylhydrazones as nucleophilic partners in cross-coupling reactions. Typically, nucleophilic reagents in coupling reactions tend to be of the organometallic variety...

Aromatic Coupling and the Scholl Reaction". Angew. Chem. Int. Ed. 52 (38): 9900–9930. doi:10.1002/anie.201210238. PMID 23852649. This reaction with phosphorus...

The Horner–Wadsworth–Emmons (HWE) reaction is a chemical reaction used in organic chemistry of stabilized phosphonate carbanions with aldehydes (or ketones)...

undesired side reaction, and frequently associated with metal-catalysed coupling reactions that utilise boronic acids (see Suzuki reaction). For a given...

Organogermanium compounds in cross-coupling reactions refers to a type of cross-coupling reaction where one of the coupling partners is an organogermanium...

This reaction is related to the Pinacol coupling reaction which also proceeds by reductive coupling of carbonyl compounds. This reductive coupling can...

strongly electron-donating groups. Abramov reaction Perkow reaction Michaelis–Becker reaction Hirao coupling Michaelis, A.; Kaehne, R. (1898). "Ueber das...

alternate N-terminal deprotection and coupling reactions. The resin can be washed between each steps. Reactions in SPPS are conducted as follows: The...