DNA-binding proteins are proteins that have DNA-binding domains and thus have a specific or general affinity for single- or double-stranded DNA. Sequence-specific...
22 KB (2,637 words) - 06:01, 3 April 2025
Transactive response DNA binding protein 43 kDa (TAR DNA-binding protein 43 or TDP-43) is a protein that in humans is encoded by the TARDBP gene. TDP-43...
40 KB (4,560 words) - 07:28, 19 July 2025
A DNA-binding domain (DBD) is an independently folded protein domain that contains at least one structural motif that recognizes double- or single-stranded...
20 KB (2,348 words) - 17:08, 16 July 2025
Single-strand DNA-binding protein (SSB) is a protein found in Escherichia coli (E. coli) bacteria, that binds to single-stranded regions of deoxyribonucleic...
4 KB (425 words) - 03:32, 25 September 2024
Lac repressor (category Bacterial proteins)
The lac repressor (LacI) is a DNA-binding protein that inhibits the expression of genes coding for proteins involved in the metabolism of lactose in bacteria...
15 KB (1,690 words) - 00:19, 20 June 2025
Transcription factor (redirect from Sequence-specific DNA-binding factor)
sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific...
75 KB (8,351 words) - 22:53, 24 June 2025
chromatin-binding proteins in eukaryotes. DamID identifies binding sites by expressing the proposed DNA-binding protein as a fusion protein with DNA methyltransferase...
18 KB (2,212 words) - 14:17, 26 April 2024
A binding protein is any protein that acts as an agent to bind two or more molecules together. Examples include: DNA-binding protein Single-strand binding...
2 KB (263 words) - 21:49, 28 December 2020
Activator (genetics) (redirect from DNA Activation)
activators function by binding sequence-specifically to a regulatory DNA site located near a promoter and making protein–protein interactions with the...
17 KB (1,961 words) - 19:02, 16 July 2025
Replication protein A (RPA) is the major protein that binds to single-stranded DNA (ssDNA) in eukaryotic cells. In vitro, RPA shows a much higher affinity...
7 KB (785 words) - 23:06, 16 February 2025
"Isolation and characterization of the gene encoding single-stranded-DNA-binding protein (SSB) from four marine Shewanella strains that differ in their temperature...
10 KB (866 words) - 23:46, 13 July 2025
protein bound to DNA often protects it from enzymatic cleavage. This makes it possible to locate a protein binding site on a particular DNA molecule. The...
3 KB (364 words) - 10:38, 28 February 2025
Inhibitor of DNA-binding/differentiation proteins, also known as ID proteins comprise a family of proteins that heterodimerize with basic helix-loop-helix...
10 KB (1,201 words) - 07:56, 20 September 2024
DNA damage-binding protein or UV-DDB is a protein complex that is responsible for repair of UV-damaged DNA. This complex is composed of two protein subunits...
6 KB (654 words) - 23:59, 31 May 2022
helicase–primase complex and a single-stranded DNA-binding protein. The human herpesvirus 1 (HHV-1) single-strand DNA-binding protein ICP8 is a 128kDa zinc metalloprotein...
10 KB (1,016 words) - 04:57, 4 July 2025
polymerase, and Single-strand DNA-binding protein) and with the DNA replication fork enhancing DNA-unwinding and DNA-replication. These results lead...
61 KB (7,458 words) - 14:41, 28 July 2025
KS, Darst SA, Berman HM, Ebright RH (2004). "Catabolite activator protein: DNA binding and transcription activation". Curr. Opin. Struct. Biol. 14 (1):...
5 KB (579 words) - 19:37, 9 November 2024
Repressor (redirect from Repressor Protein)
a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated silencers. A DNA-binding repressor...
13 KB (1,503 words) - 15:09, 18 July 2025
ZBP1 (section Z-DNA binding)
Z-DNA-binding protein 1, also known as DNA-dependent activator of IFN-regulatory factors (DAI) and DLM-1, is a protein that in humans is encoded by the...
21 KB (2,535 words) - 03:51, 20 July 2025
in the DNA. A Z-DNA high affinity binding protein, hZαADAR1, was used at varying concentrations to induce the transformation from B-DNA to Z-DNA. The smFRET...
34 KB (4,322 words) - 17:50, 16 July 2025
Lambda phage (redirect from Lambda DNA)
as the cI protein. It binds DNA in the helix-turn-helix binding motif. It regulates the transcription of the cI protein and the Cro protein. The life...
54 KB (5,954 words) - 07:52, 19 July 2025
Sex-determining region Y protein (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/transcription factor)...
42 KB (5,183 words) - 18:35, 16 July 2025
bacterial DNA binding proteins are a family of small, usually basic proteins of about 90 residues that bind DNA and are known as histone-like proteins. Since...
19 KB (2,263 words) - 01:58, 11 December 2023
distinct group of DNA-binding proteins is the DNA-binding proteins that specifically bind single-stranded DNA. In humans, replication protein A is the best-understood...
168 KB (18,024 words) - 18:52, 29 July 2025
Zinc finger (redirect from Zinc-containing DNA-binding motif)
of zinc fingers with DNA. The binding of zinc finger is found to be distinct from many other DNA-binding proteins that bind DNA through the 2-fold symmetry...
42 KB (4,905 words) - 00:52, 25 July 2025
Methyl-CpG-binding domain protein 2 is a protein that in humans is encoded by the MBD2 gene. DNA methylation is the major modification of eukaryotic genomes...
12 KB (1,442 words) - 19:46, 3 March 2023
DNA-binding proteins from starved cells (Dps) are bacterial proteins that belong to the ferritin superfamily and are characterized by strong similarities...
14 KB (1,650 words) - 14:12, 1 July 2025
P53 (redirect from Protein P53)
the active form of p53 for DNA binding and transcriptional regulation. Like 95% of human genes, TP53 encodes multiple proteins, collectively known as the...
127 KB (13,875 words) - 14:09, 31 July 2025
of a DNA sequence (e.g. a genome) and (2) they are bound by DNA-binding proteins. DNA binding sites are often associated with specialized proteins known...
21 KB (2,176 words) - 21:02, 17 August 2024
Nucleoid (section DNA supercoiling and gene expression)
DNA wrapped around an octameric complex of the histone proteins. Although bacteria do not have histones, they possess a group of DNA binding proteins...
152 KB (17,310 words) - 21:17, 12 June 2025