In immunology, epitope mapping is the process of experimentally identifying the binding site, or epitope, of an antibody on its target antigen (usually...
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T-cell epitopes. These vaccines can use multiple epitopes to increase their efficacy. To find epitopes to use for the vaccine, in silico mapping is often...
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Western blot (section Epitope mapping)
epitope mapping. The procedure of identifying an antibody's binding sites (epitopes) on the target protein is referred to as "epitope mapping." Finding...
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sandwich configuration. Additionally, it allows the mapping of epitopes as antibodies of overlapping epitopes will be associated with an attenuated signal compared...
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In immunology, a linear epitope (also sequential epitope) is an epitope—a binding site on an antigen—that is recognized by antibodies by its linear sequence...
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These are known as linear epitopes. Antigen Linear epitope Epitope mapping, finding (on an antigen protein) the epitope(s) for a specific antibody Goldsby...
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related epitope and are "binned" together. Epitope binning is referenced in the literature under different names such as epitope mapping and epitope characterization...
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Pepscan is a procedure for mapping and characterizing epitopes involving the synthesis of overlapping peptides and analysis of the peptides in enzyme-linked...
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Bacterial display (section Antibody Epitope Mapping)
of applications. These include affinity-based screening, antibody epitope mapping, the identification of peptide substrates, the identification of cell-binding...
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In 2006, Moutaftsi et al. demonstrated that epitope-mapping tools could accurately identify the epitopes responsible for 95% of the murine T-cell response...
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PMC 4083010. PMID 24492943. Gao W, Xu Y, Liu J, Ho M (May 2016). "Epitope mapping by a Wnt-blocking antibody: evidence of the Wnt binding domain in heparan...
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molecules that react against a specific antigen, each identifying a different epitope. The general procedure to produce polyclonal antibodies is as follows:...
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3.296. PMID 5910871. Tanaka T, Furukawa F, Imamura S (May 1994). "Epitope mapping for epidermolysis bullosa acquisita autoantibody by molecularly cloned...
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Lee-Chan E, Stridsberg M, Singh B (April 2014). "Vasostatin-1 antigenic epitope mapping for induction of cellular and humoral immune responses to chromogranin...
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antigens, granzyme B and Perforin release by T cells, vaccine efficacy, epitope mapping, cytotoxic T-cell activity, detection of IL-4, IL-5, and IL-13, vaccine-induced...
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Immunodeficiency Antigen Antigenicity Immunogen Superantigen Allergen Hapten Epitope Linear Conformational Mimotope Tumor antigen Antigen-antibody interaction...
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; Kanehisa, M. (2006). "MIMOX: A web tool for phage display based epitope mapping". BMC Bioinformatics. 7: 451. doi:10.1186/1471-2105-7-451. PMC 1618411...
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A peptide microarray (also commonly known as peptide chip or peptide epitope microarray) is a collection of peptides displayed on a solid surface, usually...
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Pym B, Darling SM, Goodfellow PN (1989). "The MIC2 gene product: epitope mapping and structural prediction analysis define an integral membrane protein"...
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MJ, Renouf DV, Hounsell EF, Stern PL (Apr 2002). "Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen". The Biochemical Journal...
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Old LJ (August 1994). "Fibroblast activation protein: purification, epitope mapping and induction by growth factors". International Journal of Cancer....
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Soiffer RJ, Munshi NC, Gershwin ME, Ritz J (Mar 2007). "Differential epitope mapping of antibodies to PDC-E2 in patients with hematologic malignancies after...
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and networks. There are also tools which are used for T and B cell epitope mapping, proteasomal cleavage site prediction, and TAP– peptide prediction...
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PMID 22563565. Gao, Wei; Xu, Yongmei; Liu, Jian; Ho, Mitchell (May 17, 2016). "Epitope mapping by a Wnt-blocking antibody: evidence of the Wnt binding domain in heparan...
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Menegasso AR, Pêgo PN, Santos KS, et al. (January 2015). "B-cell linear epitopes mapping of antigen-5 allergen from Polybia paulista wasp venom". The Journal...
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MeSH E05.601.690.149 – blotting, far-western MeSH E05.601.690.300 – epitope mapping MeSH E05.601.690.650 – two-hybrid system techniques MeSH E05.624.850...
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FLAG-tag, or FLAG octapeptide, or FLAG epitope, is a peptide protein tag that can be added to a protein using recombinant DNA technology, having the sequence...
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Michael G. (November 2017). "A Synthetic Glycan Microarray Enables Epitope Mapping of Plant Cell Wall Glycan-Directed Antibodies". Plant Physiology. 175...
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Peptide vaccine (section Epitope design)
Peptide-based synthetic vaccines (epitope vaccines) are subunit vaccines made from peptides. The peptides mimic the epitopes of the antigen that triggers direct...
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antibody recognizes on an antigen is called an epitope. Several antibodies can recognize the same epitope but differ in their binding affinity. The antibody...
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