Exoribonuclease II (EC 3.1.13.1, ribonuclease II, ribonuclease Q, BN ribonuclease, Escherichia coli exo-RNase II, RNase II, exoribonuclease (misleading)...
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An exoribonuclease is an exonuclease ribonuclease, which are enzymes that degrade RNA by removing terminal nucleotides from either the 5' end or the 3'...
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Ribonuclease (section Major types of exoribonucleases)
components. Ribonucleases can be divided into endoribonucleases and exoribonucleases, and comprise several sub-classes within the EC 2.7 (for the phosphorolytic...
19 KB (2,001 words) - 23:40, 2 December 2023
Ribonuclease II may refer to one of two enzymes: Ribonuclease T2 Exoribonuclease II This set index page lists enzyme articles associated with the same...
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Molecular function 3'-5'-exoribonuclease activity single-stranded DNA 3'-5' exodeoxyribonuclease activity exoribonuclease II activity metal ion binding...
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guanosine-5′-diphospho-5′-[DNA] diphosphatase EC 3.1.13.1: exoribonuclease II EC 3.1.13.2: exoribonuclease H EC 3.1.13.3: oligonucleotidase EC 3.1.13.4: poly(A)-specific...
119 KB (15,553 words) - 03:35, 27 April 2024
RNase R, or Ribonuclease R, is a 3'-->5' exoribonuclease, which belongs to the RNase II superfamily, a group of enzymes that hydrolyze RNA in the 3' -...
5 KB (579 words) - 13:25, 5 November 2022
coronavirus genome is a non-structural protein, nsp14, that is a 3’-to-5’ exoribonuclease (ExoN). This protein resides in the protein complex nsp10-nsp14 that...
9 KB (1,064 words) - 22:45, 12 January 2024
multi-protein exosome complex, which consists largely of 3′ to 5′ exoribonucleases. RNA polymerase II is known to be in effect during transcriptional termination;...
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the RNA), moving towards the bound RNA polymerase II. This exonuclease is XRN2 (5'-3' Exoribonuclease 2) in humans. This model proposes that XRN2 proceeds...
13 KB (1,631 words) - 10:55, 5 June 2024
5'-3' Exoribonuclease 2 (XRN2) also known as Dhm1-like protein is an exoribonuclease enzyme that in humans is encoded by the XRN2 gene. The human gene...
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dumbbell element (DB), cis-acting replication element (CRE) and the exoribonuclease-resistant RNA elements (xrRNA). Further, unique elements have been...
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incomplete degradation of genomic viral RNA by the host cells 5'-3' exoribonuclease 1 (XRN1). As the XRN1 degrades viral RNA, it stalls at stemloops formed...
51 KB (5,784 words) - 23:55, 12 April 2024
The protein nsp14 is a 3'-5' exoribonuclease which provides extra fidelity to the replication process. The exoribonuclease provides a proofreading function...
52 KB (5,899 words) - 20:14, 30 May 2024
all belong to the RNase PH family of RNases and are phosphorolytic exoribonucleases, meaning that they use inorganic phosphate to remove nucleotides from...
43 KB (4,585 words) - 20:57, 9 April 2024
Escherichia coli there are three enzymes: RNase II, PNPase, and RNase R. RNase R is a 3’-5’ exoribonuclease that is recruited to degrade a defective mRNA...
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Polymerase Phosphorolytic 3' to 5' exoribonuclease RNase PH PNPase Nucleotidyltransferase UTP—glucose-1-phosphate uridylyltransferase Galactose-1-phosphate...
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activity poly(A)-specific ribonuclease activity mRNA binding 3'-5'-exoribonuclease activity Cellular component P-body nucleoplasm cytoplasm perinuclear...
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Gene ontology Molecular function 3'-5'-exoribonuclease activity exoribonuclease activity protein binding RNA binding mRNA 3'-UTR AU-rich region binding...
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is that some members of the order Nidovirales encode proofreading exoribonuclease activity as part of a protein that is distinct from RdRp. Excluding...
32 KB (3,253 words) - 15:20, 19 May 2024
function nuclease activity nucleic acid binding exoribonuclease activity protein binding 3'-5'-exoribonuclease activity signal transducer activity poly(A)-specific...
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2000). "Cytosolic heat-stress proteins Hsp17.7 class I and Hsp17.3 class II of tomato act as molecular chaperones in vivo". Planta. 211 (4): 575–582....
183 KB (12,500 words) - 04:52, 9 June 2024
2 (6p21.33) DHX16: DEAH-box helicase 16 (6p21.33) DOM3Z: Decapping exoribonuclease (6p21.33) DSP: Desmoplakin gene linked to cardiomyopathy (6p24.3) ELOVL5:...
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for enriching 2'-O-Methylations guided by C/D snoRNAs by using RNA exoribonuclease (Mycoplasma genitalium RNase R, MgR) and periodate oxidation reactivity...
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1997). "Poly(A) tail shortening by a mammalian poly(A)-specific 3'-exoribonuclease". The Journal of Biological Chemistry. 272 (16): 10448–56. doi:10.1074/jbc...
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methyltransferases and – like other nidoviruses with large genomes – a proofreading exoribonuclease (ExoN), likely necessary for sufficient replication fidelity to replicate...
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Dcp1-Dcp2 complex which removes the 5' cap, allowing for the 5' to 3' exoribonuclease Xrn1 to degrade the transcript completely. The role of Dcp1-Dcp2 and...
18 KB (2,296 words) - 10:27, 5 January 2024
mature miRNAs in Caenorhabditis elegans is mediated by the 5'-to-3' exoribonuclease XRN2, also known as Rat1p. In plants, SDN (small RNA degrading nuclease)...
146 KB (16,588 words) - 05:54, 3 June 2024
Gene ontology Molecular function 3'-5'-exoribonuclease activity protein binding metal ion binding nucleic acid binding poly(A)-specific ribonuclease activity...
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the endoribonucleases can cleave the substrates so that later the exoribonucleases can work on the products. RhIB has very little activity by itself but...
15 KB (1,890 words) - 14:17, 3 December 2021