• Exoribonuclease II (EC 3.1.13.1, ribonuclease II, ribonuclease Q, BN ribonuclease, Escherichia coli exo-RNase II, RNase II, exoribonuclease (misleading)...
    2 KB (230 words) - 14:00, 26 August 2023
  • Thumbnail for Exoribonuclease
    An exoribonuclease is an exonuclease ribonuclease, which are enzymes that degrade RNA by removing terminal nucleotides from either the 5' end or the 3'...
    3 KB (237 words) - 00:26, 8 December 2021
  • Thumbnail for Ribonuclease
    components. Ribonucleases can be divided into endoribonucleases and exoribonucleases, and comprise several sub-classes within the EC 2.7 (for the phosphorolytic...
    19 KB (2,001 words) - 23:40, 2 December 2023
  • Ribonuclease II may refer to one of two enzymes: Ribonuclease T2 Exoribonuclease II This set index page lists enzyme articles associated with the same...
    408 bytes (46 words) - 15:35, 23 October 2017
  • Thumbnail for ISG20
    Molecular function 3'-5'-exoribonuclease activity single-stranded DNA 3'-5' exodeoxyribonuclease activity exoribonuclease II activity metal ion binding...
    3 KB (388 words) - 02:00, 4 March 2023
  • guanosine-5′-diphospho-5′-[DNA] diphosphatase EC 3.1.13.1: exoribonuclease II EC 3.1.13.2: exoribonuclease H EC 3.1.13.3: oligonucleotidase EC 3.1.13.4: poly(A)-specific...
    119 KB (15,553 words) - 03:35, 27 April 2024
  • RNase R, or Ribonuclease R, is a 3'-->5' exoribonuclease, which belongs to the RNase II superfamily, a group of enzymes that hydrolyze RNA in the 3' -...
    5 KB (579 words) - 13:25, 5 November 2022
  • coronavirus genome is a non-structural protein, nsp14, that is a 3’-to-5’ exoribonuclease (ExoN). This protein resides in the protein complex nsp10-nsp14 that...
    9 KB (1,064 words) - 22:45, 12 January 2024
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    multi-protein exosome complex, which consists largely of 3′ to 5′ exoribonucleases. RNA polymerase II is known to be in effect during transcriptional termination;...
    12 KB (1,429 words) - 02:12, 12 May 2024
  • the RNA), moving towards the bound RNA polymerase II. This exonuclease is XRN2 (5'-3' Exoribonuclease 2) in humans. This model proposes that XRN2 proceeds...
    13 KB (1,631 words) - 10:55, 5 June 2024
  • Thumbnail for 5'-3' exoribonuclease 2
    5'-3' Exoribonuclease 2 (XRN2) also known as Dhm1-like protein is an exoribonuclease enzyme that in humans is encoded by the XRN2 gene. The human gene...
    9 KB (1,022 words) - 12:32, 24 January 2024
  • dumbbell element (DB), cis-acting replication element (CRE) and the exoribonuclease-resistant RNA elements (xrRNA). Further, unique elements have been...
    22 KB (2,410 words) - 17:57, 29 December 2023
  • Thumbnail for Flavivirus
    incomplete degradation of genomic viral RNA by the host cells 5'-3' exoribonuclease 1 (XRN1). As the XRN1 degrades viral RNA, it stalls at stemloops formed...
    51 KB (5,784 words) - 23:55, 12 April 2024
  • Thumbnail for SARS-related coronavirus
    The protein nsp14 is a 3'-5' exoribonuclease which provides extra fidelity to the replication process. The exoribonuclease provides a proofreading function...
    52 KB (5,899 words) - 20:14, 30 May 2024
  • Thumbnail for Exosome complex
    all belong to the RNase PH family of RNases and are phosphorolytic exoribonucleases, meaning that they use inorganic phosphate to remove nucleotides from...
    43 KB (4,585 words) - 20:57, 9 April 2024
  • Thumbnail for Non-stop decay
    Escherichia coli there are three enzymes: RNase II, PNPase, and RNase R. RNase R is a 3’-5’ exoribonuclease that is recruited to degrade a defective mRNA...
    7 KB (1,014 words) - 04:04, 10 June 2023
  • Thumbnail for Cyclic GMP-AMP synthase
    Polymerase Phosphorolytic 3' to 5' exoribonuclease RNase PH PNPase Nucleotidyltransferase UTP—glucose-1-phosphate uridylyltransferase Galactose-1-phosphate...
    5 KB (514 words) - 18:35, 23 January 2024
  • Thumbnail for Nocturnin
    activity poly(A)-specific ribonuclease activity mRNA binding 3'-5'-exoribonuclease activity Cellular component P-body nucleoplasm cytoplasm perinuclear...
    7 KB (796 words) - 21:56, 23 November 2023
  • Thumbnail for Exosome component 9
    Gene ontology Molecular function 3'-5'-exoribonuclease activity exoribonuclease activity protein binding RNA binding mRNA 3'-UTR AU-rich region binding...
    8 KB (797 words) - 12:21, 8 May 2024
  • Thumbnail for Orthornavirae
    is that some members of the order Nidovirales encode proofreading exoribonuclease activity as part of a protein that is distinct from RdRp. Excluding...
    32 KB (3,253 words) - 15:20, 19 May 2024
  • Thumbnail for CNOT7
    function nuclease activity nucleic acid binding exoribonuclease activity protein binding 3'-5'-exoribonuclease activity signal transducer activity poly(A)-specific...
    10 KB (1,308 words) - 08:33, 10 February 2024
  • Thumbnail for Stress granule
    2000). "Cytosolic heat-stress proteins Hsp17.7 class I and Hsp17.3 class II of tomato act as molecular chaperones in vivo". Planta. 211 (4): 575–582....
    183 KB (12,500 words) - 04:52, 9 June 2024
  • Thumbnail for Chromosome 6
    2 (6p21.33) DHX16: DEAH-box helicase 16 (6p21.33) DOM3Z: Decapping exoribonuclease (6p21.33) DSP: Desmoplakin gene linked to cardiomyopathy (6p24.3) ELOVL5:...
    35 KB (2,420 words) - 20:47, 13 May 2024
  • for enriching 2'-O-Methylations guided by C/D snoRNAs by using RNA exoribonuclease (Mycoplasma genitalium RNase R, MgR) and periodate oxidation reactivity...
    31 KB (3,791 words) - 13:33, 9 January 2024
  • Thumbnail for Poly(A)-specific ribonuclease
    1997). "Poly(A) tail shortening by a mammalian poly(A)-specific 3'-exoribonuclease". The Journal of Biological Chemistry. 272 (16): 10448–56. doi:10.1074/jbc...
    11 KB (1,338 words) - 19:41, 9 April 2024
  • methyltransferases and – like other nidoviruses with large genomes – a proofreading exoribonuclease (ExoN), likely necessary for sufficient replication fidelity to replicate...
    7 KB (748 words) - 20:41, 26 March 2024
  • Dcp1-Dcp2 complex which removes the 5' cap, allowing for the 5' to 3' exoribonuclease Xrn1 to degrade the transcript completely. The role of Dcp1-Dcp2 and...
    18 KB (2,296 words) - 10:27, 5 January 2024
  • Thumbnail for MicroRNA
    mature miRNAs in Caenorhabditis elegans is mediated by the 5'-to-3' exoribonuclease XRN2, also known as Rat1p. In plants, SDN (small RNA degrading nuclease)...
    146 KB (16,588 words) - 05:54, 3 June 2024
  • Thumbnail for TOE1
    Gene ontology Molecular function 3'-5'-exoribonuclease activity protein binding metal ion binding nucleic acid binding poly(A)-specific ribonuclease activity...
    5 KB (431 words) - 18:37, 11 October 2022
  • the endoribonucleases can cleave the substrates so that later the exoribonucleases can work on the products. RhIB has very little activity by itself but...
    15 KB (1,890 words) - 14:17, 3 December 2021