• Thumbnail for Exosome component 10
    Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which (sometimes called PM/Scl-100) is part of the exosome complex...
    7 KB (858 words) - 12:20, 8 May 2024
  • Thumbnail for Exosome component 2
    Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. Mammalian mRNAs contain AU-rich elements (AREs)...
    8 KB (1,045 words) - 03:28, 26 February 2024
  • Thumbnail for Exosome component 1
    encoded by the EXOSC1 gene. This gene encodes a core component of the exosome complex. The mammalian exosome is required for rapid degradation of AU rich element-containing...
    7 KB (782 words) - 23:17, 29 March 2024
  • Thumbnail for Exosome component 7
    Exosome component 7, also known as EXOSC7, is a human gene, the protein product of which is part of the exosome complex. Exosome component 7 has been shown...
    6 KB (717 words) - 23:21, 29 March 2024
  • Thumbnail for Exosome component 8
    Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex. Exosome component 8 has been shown...
    6 KB (614 words) - 06:09, 18 March 2024
  • Thumbnail for Exosome component 3
    Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex. Mutations in EXOSC3 cause pontocerebellar hypoplasia...
    6 KB (702 words) - 23:19, 29 March 2024
  • Thumbnail for Exosome component 4
    Exosome component 4, also known as EXOSC4, is a human gene, which is part of the exosome complex. Exosome component 4 has been shown to interact with...
    6 KB (777 words) - 05:33, 1 April 2024
  • Thumbnail for Exosome component 9
    Exosome component 9, also known as EXOSC9, is a human gene, the protein product of which (sometimes called RRP45 or PM/Scl-75) is part of the exosome...
    8 KB (797 words) - 12:21, 8 May 2024
  • Thumbnail for Exosome complex
    The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of degrading various types of...
    43 KB (4,589 words) - 17:33, 6 November 2024
  • Thumbnail for Exosome component 6
    the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation. Exosome component 6 has been shown to interact with Exosome component...
    4 KB (516 words) - 23:20, 29 March 2024
  • Thumbnail for Exosome component 5
    Exosome component 5, also known as EXOSC5, is a human gene, which is part of the exosome complex. Biallelic pathogenic variation in EXOSC5 causes autosomal...
    9 KB (971 words) - 15:37, 20 March 2024
  • Thumbnail for TRAMP complex
    contact with various components of exosome, Mtr4p helps in proper addition of RNA substrates of TRAMP complex to nuclear exosome. The difference between...
    19 KB (2,325 words) - 20:23, 15 May 2025
  • Thumbnail for DIS3L
    RNase enzyme homologous to the yeast protein Rrp44, and can be part of the exosome complex in the cytoplasm of eukaryotic cells. GRCh38: Ensembl release 89:...
    1 KB (196 words) - 01:58, 4 March 2023
  • Thumbnail for Serum amyloid P component
    The serum amyloid P component (SAP) is the identical serum form of the amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal...
    6 KB (744 words) - 11:38, 20 October 2023
  • Thumbnail for Complement component 3
    Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the...
    15 KB (1,758 words) - 20:15, 22 May 2025
  • Thumbnail for Telomerase RNA component
    exoribonucleolytic degradation. Extended hTR transcripts are also degraded by the RNA exosome. The 5’ ends of hTR transcripts are also additionally processed. TGS-1...
    23 KB (2,549 words) - 19:15, 25 May 2025
  • Autoantibodies often found in these patients are the anti-PM/Scl (anti-exosome) antibodies. The symptoms that are seen most often are typical symptoms...
    6 KB (598 words) - 07:29, 19 June 2023
  • Thumbnail for Complement component 9
    Complement component 9 (C9) is a MACPF protein involved in the complement system, which is part of the innate immune system. Once activated, about 12-18...
    7 KB (789 words) - 20:10, 20 January 2025
  • Thumbnail for Complement component 4B
    Complement component 4B (Chido blood group) is a kind of the Complement component 4 protein that in humans is encoded by the C4B gene. This gene encodes...
    8 KB (1,049 words) - 07:55, 3 January 2024
  • Thumbnail for Complement component 5
    Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...
    9 KB (1,114 words) - 05:29, 8 January 2024
  • Thumbnail for Microvesicle
    to be larger, on average, than intracellularly-generated EVs known as exosomes. Microvesicles play a role in intercellular communication and can transport...
    54 KB (6,074 words) - 21:14, 22 May 2025
  • Thumbnail for Complement component 2
    system and the Complement component 2 protein attaches to Complement system 4 resulting in an immune response. Complement component 2 protein is critical...
    16 KB (2,068 words) - 18:45, 14 January 2024
  • nanocrystals, micelles, lipid, polymeric, and silica nanoparticles, and exosomes are all drug carriers used in follicular drug delivery. When each of these...
    61 KB (6,631 words) - 12:18, 24 May 2025
  • Thumbnail for Pyruvate dehydrogenase (lipoamide) beta
    dehydrogenase (lipoamide) beta, also known as pyruvate dehydrogenase E1 component subunit beta, mitochondrial or PDHE1-B is an enzyme that in humans is...
    20 KB (2,645 words) - 23:33, 24 May 2025
  • 2005). "RNA degradation by the exosome is promoted by a nuclear polyadenylation complex". Cell. 121 (5): 713–24. doi:10.1016/j.cell.2005.04.029. PMID 15935758...
    57 KB (7,094 words) - 23:56, 6 August 2024
  • agreed to acquire Quad Technologies. In August 2018, the company acquired Exosome Diagnostics for $250 million plus up to an additional $325 million in milestone...
    12 KB (826 words) - 07:17, 31 August 2024
  • Thumbnail for Complement component 1s
    Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system...
    10 KB (1,195 words) - 05:11, 25 December 2023
  • Thumbnail for Complement component 1r
    Biochemistry. 57: 321–47. doi:10.1146/annurev.bi.57.070188.001541. PMID 3052276. "Entrez Gene: C1R complement component 1, r subcomponent". Thielens NM...
    10 KB (1,273 words) - 20:03, 12 May 2024
  • 10 microns or more, although the vast majority of EVs are smaller than 200 nm. EVs can be divided according to size and synthesis route into exosomes...
    63 KB (6,967 words) - 05:40, 1 April 2025
  • Thumbnail for TTC37
    tetratricopeptide repeat domains. TTC37 is a component of the Ski complex which is involved in exosome mediated RNA decay. It is localized in the cytoplasmatic...
    3 KB (289 words) - 02:12, 10 March 2024