• Thumbnail for Exosome component 2
    Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. Mammalian mRNAs contain AU-rich elements (AREs)...
    8 KB (1,045 words) - 03:28, 26 February 2024
  • Thumbnail for Exosome component 7
    component 7 has been shown to interact with: Exosome component 1, Exosome component 2, and Exosome component 6. GRCh38: Ensembl release 89: ENSG00000075914...
    6 KB (717 words) - 04:09, 15 July 2025
  • Thumbnail for Exosome component 4
    Exosome component 4, also known as EXOSC4, is a human gene, which is part of the exosome complex. Exosome component 4 has been shown to interact with...
    6 KB (777 words) - 03:30, 18 June 2025
  • Thumbnail for Exosome component 10
    Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which (sometimes called PM/Scl-100) is part of the exosome complex...
    7 KB (858 words) - 12:20, 8 May 2024
  • Thumbnail for Exosome component 1
    encoded by the EXOSC1 gene. This gene encodes a core component of the exosome complex. The mammalian exosome is required for rapid degradation of AU rich element-containing...
    7 KB (782 words) - 23:17, 29 March 2024
  • Thumbnail for Exosome component 3
    Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex. Mutations in EXOSC3 cause pontocerebellar hypoplasia...
    6 KB (702 words) - 21:41, 15 July 2025
  • Thumbnail for Exosome component 5
    Exosome component 5, also known as EXOSC5, is a human gene, which is part of the exosome complex. Biallelic pathogenic variation in EXOSC5 causes autosomal...
    9 KB (971 words) - 15:37, 20 March 2024
  • Thumbnail for Exosome component 9
    Exosome component 9, also known as EXOSC9, is a human gene, the protein product of which (sometimes called RRP45 or PM/Scl-75) is part of the exosome...
    8 KB (797 words) - 12:21, 8 May 2024
  • Thumbnail for Exosome complex
    The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of degrading various types of...
    43 KB (4,589 words) - 17:33, 6 November 2024
  • Thumbnail for Complement component 2
    system and the Complement component 2 protein attaches to Complement system 4 resulting in an immune response. Complement component 2 protein is critical for...
    16 KB (2,068 words) - 18:45, 14 January 2024
  • Thumbnail for Telomerase RNA component
    exoribonucleolytic degradation. Extended hTR transcripts are also degraded by the RNA exosome. The 5’ ends of hTR transcripts are also additionally processed. TGS-1...
    23 KB (2,549 words) - 19:15, 25 May 2025
  • Thumbnail for Beta-2 microglobulin
    β2 microglobulin (B2M) is a component of MHC class I molecules. MHC class I molecules have α1, α2, and α3 proteins which are present on all nucleated...
    17 KB (2,118 words) - 05:47, 29 September 2024
  • Thumbnail for Desmoglein-2
    epithelial-derived cell lines. Desmoglein-2 is the only desmoglein isoform expressed in cardiomyocytes. Desmoglein-2 is an integral component of desmosomes, which are...
    20 KB (2,282 words) - 19:08, 9 June 2025
  • Thumbnail for Alpha-2-Macroglobulin
    composed of multiple domains, as predicted by homology with complement component C3". The Biochemical Journal. 407 (1): 23–30. doi:10.1042/BJ20070764....
    14 KB (1,667 words) - 14:59, 11 June 2025
  • Autoantibodies often found in these patients are the anti-PM/Scl (anti-exosome) antibodies. The symptoms that are seen most often are typical symptoms...
    6 KB (597 words) - 04:26, 20 June 2025
  • Thumbnail for Microvesicle
    to be larger, on average, than intracellularly-generated EVs known as exosomes. Microvesicles play a role in intercellular communication and can transport...
    54 KB (6,074 words) - 21:14, 22 May 2025
  • Thumbnail for Complement component 5
    Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...
    9 KB (1,114 words) - 04:01, 15 July 2025
  • Thumbnail for Serum amyloid P component
    The serum amyloid P component (SAP) is the identical serum form of the amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal...
    6 KB (744 words) - 11:38, 20 October 2023
  • degradation due to the combined activity of poly-adenylating polymerases and exosome complexes. CUT transcription occurs through RNA Polymerase II and initiates...
    18 KB (2,296 words) - 10:27, 5 January 2024
  • Thumbnail for TACSTD2
    Kimura S, Fujiki K, Fujimaki T, Kanai A (2004). "Mutations in the membrane component, chromosome 1, surface marker 1 (M1S1) gene in gelatinous drop-like corneal...
    11 KB (1,362 words) - 20:12, 9 October 2024
  • Thumbnail for Pyruvate dehydrogenase (lipoamide) beta
    dehydrogenase (lipoamide) beta, also known as pyruvate dehydrogenase E1 component subunit beta, mitochondrial or PDHE1-B is an enzyme that in humans is...
    20 KB (2,645 words) - 23:33, 24 May 2025
  • Thumbnail for MASP2 (protein)
    mannose residues on the surface of a pathogen, MASP-2 is activated to cleave complement components C4 and C2 into C4a, C4b, C2a, and C2b. MASP1 (protein)...
    11 KB (1,484 words) - 10:42, 11 July 2025
  • Thumbnail for Complement component 4B
    Complement component 4B (Chido blood group) is a kind of the Complement component 4 protein that in humans is encoded by the C4B gene. This gene encodes...
    8 KB (1,049 words) - 07:55, 3 January 2024
  • Thumbnail for TRAMP complex
    contact with various components of exosome, Mtr4p helps in proper addition of RNA substrates of TRAMP complex to nuclear exosome. The difference between...
    19 KB (2,325 words) - 20:23, 15 May 2025
  • Thumbnail for CSPG4
    CSPG4 (redirect from Neuron-glial antigen 2)
    melanoma-associated chondroitin sulfate proteoglycan (MCSP) or neuron-glial antigen 2 (NG2), is a chondroitin sulfate proteoglycan that in humans is encoded by...
    12 KB (1,498 words) - 13:18, 18 June 2025
  • Thumbnail for Myelin P2 protein
    Myelin P2 protein also peripheral myelin protein 2, is a protein that in humans is encoded by the PMP2 gene. Myelin protein P2 is a constituent of peripheral...
    5 KB (610 words) - 11:01, 27 April 2025
  • Thumbnail for Lipocalin-2
    is not always reliable because creatinine and NGAL measure different components of renal (dys)function. The demonstration that NGAL does not rise in the...
    16 KB (1,968 words) - 07:49, 26 August 2024
  • Thumbnail for Alpha-2-HS-glycoprotein
    alpha-2-HS-glycoprotein (AHSG, Alpha-2-Heremans-Schmid Glycoprotein) also known as fetuin-A is a protein that in humans is encoded by the AHSG gene. Fetuin-A...
    14 KB (1,711 words) - 19:17, 11 July 2025
  • Thumbnail for Angiotensin-converting enzyme 2
    Angiotensin-converting enzyme 2 (ACE2) is an enzyme that can be found either attached to the membrane of cells (mACE2) in the intestines, kidney, testis...
    45 KB (5,270 words) - 19:19, 10 June 2025
  • Thumbnail for DLST
    Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial is an enzyme that in humans is encoded...
    8 KB (968 words) - 18:03, 20 November 2023