the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation. Exosome component 6 has been shown to interact with Exosome component...
4 KB (516 words) - 23:20, 29 March 2024
Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex. Exosome component 8 has been shown...
6 KB (614 words) - 06:09, 18 March 2024
component 7 has been shown to interact with: Exosome component 1, Exosome component 2, and Exosome component 6. GRCh38: Ensembl release 89: ENSG00000075914...
6 KB (717 words) - 04:09, 15 July 2025
protein 46. Exosome component 1 has been shown to interact with: Exosome component 5, Exosome component 6, and Exosome component 7. GRCh38: Ensembl release...
7 KB (782 words) - 23:17, 29 March 2024
Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. Mammalian mRNAs contain AU-rich elements (AREs)...
8 KB (1,045 words) - 03:28, 26 February 2024
Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which (sometimes called PM/Scl-100) is part of the exosome complex...
7 KB (858 words) - 12:20, 8 May 2024
The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of degrading various types of...
43 KB (4,589 words) - 17:33, 6 November 2024
Exosome component 4, also known as EXOSC4, is a human gene, which is part of the exosome complex. Exosome component 4 has been shown to interact with...
6 KB (777 words) - 03:30, 18 June 2025
Exosome component 5, also known as EXOSC5, is a human gene, which is part of the exosome complex. Biallelic pathogenic variation in EXOSC5 causes autosomal...
9 KB (971 words) - 15:37, 20 March 2024
Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex. Mutations in EXOSC3 cause pontocerebellar hypoplasia...
6 KB (702 words) - 21:41, 15 July 2025
Exosome component 9, also known as EXOSC9, is a human gene, the protein product of which (sometimes called RRP45 or PM/Scl-75) is part of the exosome...
8 KB (797 words) - 12:21, 8 May 2024
Complement component 6 is a protein that in humans is encoded by the C6 gene. Complement component 6 is a protein involved in the complement system. It...
7 KB (910 words) - 04:01, 15 July 2025
system and the Complement component 2 protein attaches to Complement system 4 resulting in an immune response. Complement component 2 protein is critical...
16 KB (2,068 words) - 18:45, 14 January 2024
exoribonucleolytic degradation. Extended hTR transcripts are also degraded by the RNA exosome. The 5’ ends of hTR transcripts are also additionally processed. TGS-1...
23 KB (2,549 words) - 19:15, 25 May 2025
contact with various components of exosome, Mtr4p helps in proper addition of RNA substrates of TRAMP complex to nuclear exosome. The difference between...
19 KB (2,325 words) - 20:23, 15 May 2025
N-acetylglucosamine-6-sulfatase (EC 3.1.6.14, glucosamine (N-acetyl)-6-sulfatase, systematic name N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase) is...
3 KB (394 words) - 22:02, 15 July 2025
The serum amyloid P component (SAP) is the identical serum form of the amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal...
6 KB (744 words) - 11:38, 20 October 2023
Autoantibodies often found in these patients are the anti-PM/Scl (anti-exosome) antibodies. The symptoms that are seen most often are typical symptoms...
6 KB (597 words) - 04:26, 20 June 2025
degradation due to the combined activity of poly-adenylating polymerases and exosome complexes. CUT transcription occurs through RNA Polymerase II and initiates...
18 KB (2,296 words) - 10:27, 5 January 2024
Complement component 9 (C9) is a MACPF protein involved in the complement system, which is part of the innate immune system. Once activated, about 12-18...
7 KB (789 words) - 20:10, 20 January 2025
Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the...
15 KB (1,758 words) - 15:36, 20 June 2025
Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system...
10 KB (1,195 words) - 05:11, 25 December 2023
genetics of the C1S subcomponent of the first complement component". Complement and Inflammation. 6 (2): 81–7. doi:10.1159/000463078. PMID 2541966. Arlaud...
10 KB (1,273 words) - 20:03, 12 May 2024
Complement component 4B (Chido blood group) is a kind of the Complement component 4 protein that in humans is encoded by the C4B gene. This gene encodes...
8 KB (1,049 words) - 07:55, 3 January 2024
Gamma-glutamyltransferase 6 is a protein that in humans is encoded by the GGT6 gene. GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene...
1 KB (152 words) - 21:10, 18 September 2024
sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction...
10 KB (1,119 words) - 03:27, 10 July 2025
C4A (category Genes on human chromosome 6)
Complement C4-A is a kind of the Complement component 4 protein that in humans is encoded by the C4A gene. This gene encodes the acidic form of complement...
13 KB (1,679 words) - 21:56, 11 June 2025
Archaea: not observed in Haloferax while the exosome polynucleotidylates RNA in Sulfolobus". EMBO Reports. 6 (12): 1188–93. doi:10.1038/sj.embor.7400571...
57 KB (7,094 words) - 23:56, 6 August 2024
Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...
9 KB (1,114 words) - 04:01, 15 July 2025
agreed to acquire Quad Technologies. In August 2018, the company acquired Exosome Diagnostics for $250 million plus up to an additional $325 million in milestone...
12 KB (826 words) - 07:17, 31 August 2024