• Thumbnail for Exosome component 6
    the exosome and recruit it to unstable mRNAs, thereby promoting their rapid degradation. Exosome component 6 has been shown to interact with Exosome component...
    4 KB (516 words) - 23:20, 29 March 2024
  • Thumbnail for Exosome component 8
    Exosome component 8, also known as EXOSC8, is a human gene, the protein product of which is part of the exosome complex. Exosome component 8 has been shown...
    6 KB (614 words) - 06:09, 18 March 2024
  • Thumbnail for Exosome component 7
    component 7 has been shown to interact with: Exosome component 1, Exosome component 2, and Exosome component 6. GRCh38: Ensembl release 89: ENSG00000075914...
    6 KB (717 words) - 04:09, 15 July 2025
  • Thumbnail for Exosome component 1
    protein 46. Exosome component 1 has been shown to interact with: Exosome component 5, Exosome component 6, and Exosome component 7. GRCh38: Ensembl release...
    7 KB (782 words) - 23:17, 29 March 2024
  • Thumbnail for Exosome component 2
    Exosome component 2, also known as EXOSC2, is a protein which in humans is encoded by the EXOSC2 gene. Mammalian mRNAs contain AU-rich elements (AREs)...
    8 KB (1,045 words) - 03:28, 26 February 2024
  • Thumbnail for Exosome component 10
    Exosome component 10, also known as EXOSC10, is a human gene, the protein product of which (sometimes called PM/Scl-100) is part of the exosome complex...
    7 KB (858 words) - 12:20, 8 May 2024
  • Thumbnail for Exosome complex
    The exosome complex (or PM/Scl complex, often just called the exosome) is a multi-protein intracellular complex capable of degrading various types of...
    43 KB (4,589 words) - 17:33, 6 November 2024
  • Thumbnail for Exosome component 4
    Exosome component 4, also known as EXOSC4, is a human gene, which is part of the exosome complex. Exosome component 4 has been shown to interact with...
    6 KB (777 words) - 03:30, 18 June 2025
  • Thumbnail for Exosome component 5
    Exosome component 5, also known as EXOSC5, is a human gene, which is part of the exosome complex. Biallelic pathogenic variation in EXOSC5 causes autosomal...
    9 KB (971 words) - 15:37, 20 March 2024
  • Thumbnail for Exosome component 3
    Exosome component 3, also known as EXOSC3, is a human gene, which is part of the exosome complex. Mutations in EXOSC3 cause pontocerebellar hypoplasia...
    6 KB (702 words) - 21:41, 15 July 2025
  • Thumbnail for Exosome component 9
    Exosome component 9, also known as EXOSC9, is a human gene, the protein product of which (sometimes called RRP45 or PM/Scl-75) is part of the exosome...
    8 KB (797 words) - 12:21, 8 May 2024
  • Thumbnail for Complement component 6
    Complement component 6 is a protein that in humans is encoded by the C6 gene. Complement component 6 is a protein involved in the complement system. It...
    7 KB (910 words) - 04:01, 15 July 2025
  • Thumbnail for Complement component 2
    system and the Complement component 2 protein attaches to Complement system 4 resulting in an immune response. Complement component 2 protein is critical...
    16 KB (2,068 words) - 18:45, 14 January 2024
  • Thumbnail for Telomerase RNA component
    exoribonucleolytic degradation. Extended hTR transcripts are also degraded by the RNA exosome. The 5’ ends of hTR transcripts are also additionally processed. TGS-1...
    23 KB (2,549 words) - 19:15, 25 May 2025
  • Thumbnail for TRAMP complex
    contact with various components of exosome, Mtr4p helps in proper addition of RNA substrates of TRAMP complex to nuclear exosome. The difference between...
    19 KB (2,325 words) - 20:23, 15 May 2025
  • Thumbnail for N-acetylglucosamine-6-sulfatase
    N-acetylglucosamine-6-sulfatase (EC 3.1.6.14, glucosamine (N-acetyl)-6-sulfatase, systematic name N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase) is...
    3 KB (394 words) - 22:02, 15 July 2025
  • Thumbnail for Serum amyloid P component
    The serum amyloid P component (SAP) is the identical serum form of the amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal...
    6 KB (744 words) - 11:38, 20 October 2023
  • Autoantibodies often found in these patients are the anti-PM/Scl (anti-exosome) antibodies. The symptoms that are seen most often are typical symptoms...
    6 KB (597 words) - 04:26, 20 June 2025
  • degradation due to the combined activity of poly-adenylating polymerases and exosome complexes. CUT transcription occurs through RNA Polymerase II and initiates...
    18 KB (2,296 words) - 10:27, 5 January 2024
  • Thumbnail for Complement component 9
    Complement component 9 (C9) is a MACPF protein involved in the complement system, which is part of the innate immune system. Once activated, about 12-18...
    7 KB (789 words) - 20:10, 20 January 2025
  • Thumbnail for Complement component 3
    Complement component 3, often simply called C3, is a protein of the immune system that is found primarily in the blood. It plays a central role in the...
    15 KB (1,758 words) - 15:36, 20 June 2025
  • Thumbnail for Complement component 1s
    Complement component 1s (EC 3.4.21.42, C1 esterase, activated complement C1s, complement C overbar 1r, C1s) is a protein involved in the complement system...
    10 KB (1,195 words) - 05:11, 25 December 2023
  • Thumbnail for Complement component 1r
    genetics of the C1S subcomponent of the first complement component". Complement and Inflammation. 6 (2): 81–7. doi:10.1159/000463078. PMID 2541966. Arlaud...
    10 KB (1,273 words) - 20:03, 12 May 2024
  • Thumbnail for Complement component 4B
    Complement component 4B (Chido blood group) is a kind of the Complement component 4 protein that in humans is encoded by the C4B gene. This gene encodes...
    8 KB (1,049 words) - 07:55, 3 January 2024
  • Thumbnail for Gamma-glutamyltransferase 6
    Gamma-glutamyltransferase 6 is a protein that in humans is encoded by the GGT6 gene. GGT6 belongs to the gamma-glutamyltransferase (GGT; EC 2.3.2.2) gene...
    1 KB (152 words) - 21:10, 18 September 2024
  • Thumbnail for UDP-glucose 6-dehydrogenase
    sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction...
    10 KB (1,119 words) - 03:27, 10 July 2025
  • Thumbnail for C4A
    C4A (category Genes on human chromosome 6)
    Complement C4-A is a kind of the Complement component 4 protein that in humans is encoded by the C4A gene. This gene encodes the acidic form of complement...
    13 KB (1,679 words) - 21:56, 11 June 2025
  • Archaea: not observed in Haloferax while the exosome polynucleotidylates RNA in Sulfolobus". EMBO Reports. 6 (12): 1188–93. doi:10.1038/sj.embor.7400571...
    57 KB (7,094 words) - 23:56, 6 August 2024
  • Thumbnail for Complement component 5
    Complement component 5 is a protein that in humans is encoded by the C5 gene. Complement component 5 is involved in the complement system. It is cleaved...
    9 KB (1,114 words) - 04:01, 15 July 2025
  • agreed to acquire Quad Technologies. In August 2018, the company acquired Exosome Diagnostics for $250 million plus up to an additional $325 million in milestone...
    12 KB (826 words) - 07:17, 31 August 2024