Folate-binding protein (FBP) are proteins that bind folate, typically the folate receptors and reduced folate carrier. FBP can be a marker for ovarian...
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Lipopolysaccharide-binding protein C4b-binding protein Rap GTP-binding protein Calmodulin-binding proteins Iron-binding proteins Thyroxine-binding proteins Folate-binding...
2 KB (263 words) - 21:49, 28 December 2020
Folate receptor 1 (Folate receptor alpha, FOLR1) is a protein that in humans is encoded by the FOLR1 gene. The protein encoded by this gene is a member...
15 KB (1,756 words) - 15:34, 10 February 2025
folate (folic acid), to a molecule/drug to form a "folate conjugate". Based on the natural high affinity of folate for the folate receptor protein (FR)...
24 KB (3,023 words) - 00:54, 12 February 2024
phytates and phenolics. Pea proteins also contain high levels of folate.[citation needed] This can help increase dietary folate levels, which is beneficial...
19 KB (2,399 words) - 22:25, 26 December 2024
enzymatic cofactors required for many folate-dependent processes such as folate-dependent one-carbon metabolism. These proteins are attached to the membrane by...
2 KB (210 words) - 03:35, 17 May 2022
The proton-coupled folate transporter is a protein that in humans is encoded by the SLC46A1 gene. The major physiological roles of PCFTs are in mediating...
22 KB (2,649 words) - 18:32, 9 June 2024
Reduced folate carrier 1 Intestinal folate carrier 1 Solute carrier family Folate-binding protein Reduced folate carrier family GRCh38: Ensembl release...
11 KB (1,284 words) - 13:04, 3 May 2025
FOLR2 (redirect from Folate receptor 2)
Folate receptor beta is a protein that in humans is encoded by the FOLR2 gene. The protein encoded by this gene is a member of the folate receptor (FOLR)...
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Kerr. In 1984, Cook and Wagner demonstrated that a liver cytosolic folate binding protein is identical to GNMT. The human GMNT gene was cloned in 2000 by...
27 KB (3,150 words) - 08:39, 31 December 2024
Antiporter (redirect from Exchanger (protein))
move folate into the cell against its concentration gradient. The RFC protein can transport folates, reduced folates, the derivatives of reduced folate, and...
60 KB (7,840 words) - 00:16, 11 February 2025
MTRR (gene) (section Protein binding)
methionine synthase (MTR). The folate cycle is linked to homocysteine metabolism via MTR. Circulating blood folate (5-methyl tetrahydrofolate, 5-MTHF)...
44 KB (5,274 words) - 18:33, 3 May 2024
Dihydrofolate reductase (category Protein domains)
substrate binding in EcDHFR and R67 DHFR DHFR mutations cause dihydrofolate reductase deficiency, a rare autosomal recessive inborn error of folate metabolism...
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in the protein now faces the other side of the plasma membrane. The carrier protein substrate is released at that site, according to its binding affinity...
26 KB (2,656 words) - 14:08, 8 March 2025
of protein-coding gene that are predicted to encode oxidoreductase activity, dihydropteroate synthase (part of folate metabolism) or DNA-binding response...
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Heme carrier protein 1 (HCP1) was originally identified as mediating heme-Fe transport although it later emerged that it was the SLC46A1 folate transporter...
12 KB (1,428 words) - 18:07, 13 February 2024
Cassava (redirect from Novel cap-binding protein)
(27 mg/100 g), and vitamin C (20.6 mg/100 g). Cassava roots contain little protein, whereas the leaves are rich in it, except for being low in methionine...
84 KB (8,388 words) - 09:17, 27 April 2025
Methylenetetrahydrofolate reductase (category Human proteins)
with lower plasma folate levels are at risk for elevated plasma homocysteine levels. In studies of human recombinant MTHFR, the protein encoded by 677T...
36 KB (3,876 words) - 10:16, 9 May 2025
Enzyme inhibitor (section Slow binding)
and vertebrate sources by various classes of folate analogs". Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 869 (3):...
104 KB (11,579 words) - 19:29, 18 September 2024
Formylation (category Proteins)
antifolate inhibitor with proton-coupled folate transporter and folate receptor selectivity over the reduced folate carrier that inhibits β-glycinamide ribonucleotide...
25 KB (2,838 words) - 19:16, 23 November 2024
Flow-based programming Fluff Busting Purity, a web browser extension Folate-binding protein Fructose 1,6-bisphosphate Fructose 1,6-bisphosphatase Funds for...
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Enzyme (section Substrate binding)
directly disrupting binding and catalysis, but many are far from the active site and reduce activity by destabilising the protein structure, or affecting...
99 KB (10,086 words) - 08:21, 4 April 2025
can also result from low intake, immune gastritis, low presence of binding proteins, or use of certain medications. Vegans—people who choose to not consume...
111 KB (12,067 words) - 16:16, 17 May 2025
known as folate receptor 4, folate receptor delta or IZUMO1R is a protein that in humans is encoded by the FOLR4 gene. Juno is a member of the folate receptor...
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skin pigmentation was the breakdown of folate in reaction to ultraviolet radiation; the relationship between folate breakdown induced by ultraviolet radiation...
75 KB (8,506 words) - 23:45, 15 May 2025
Haptocorrin (redirect from Protein R)
National Library of Medicine. "Entrez Gene: transcobalamin I (vitamin B12 binding protein". Pettit JD, Moss P (2006). Essential Haematology 5e (Essential). Blackwell...
14 KB (1,810 words) - 14:01, 10 September 2024
cleft consists of the GAR binding site and the folate-binding pocket. The folate-binding pocket is delineated by pteridine-binding cleft, the formyl transfer...
16 KB (1,775 words) - 03:03, 10 March 2025
Reduced Folate Carrier (RFC) Family (TC# 2.A.48) is a group of transport proteins that is part of the major facilitator superfamily. RFCs take up folate, reduced...
5 KB (624 words) - 13:41, 22 April 2022
from foods, since acid is needed to split B12 from food proteins and salivary binding proteins. This process is thought to be the most common cause of...
117 KB (12,875 words) - 17:00, 15 May 2025
Small intestine (section Gene and protein expression)
The corresponding specific proteins are expressed in glandular cells of the mucosa, such as fatty acid binding protein FABP6. Most of the more specifically...
30 KB (3,458 words) - 01:45, 14 May 2025