During development, these cells will differentiate into primordial germ cells, migrate to the location of the gonad, and form the germline of the animal...
33 KB (3,984 words) - 13:17, 22 January 2025
In biology and genetics, the germline is the population of a multicellular organism's cells that develop into germ cells. In other words, they are the...
17 KB (2,066 words) - 18:19, 6 February 2025
RNA-binding protein (section Germline development)
to RBPs' functions in germline development, post-transcriptional control also plays a significant role in somatic development. Differing from RBPs that...
39 KB (4,540 words) - 15:46, 4 November 2024
Germ cell (redirect from Germline cell)
and they only divide by mitosis. The lineage of germ cells is called the germline. Germ cell specification begins during cleavage in many animals or in the...
31 KB (4,040 words) - 22:46, 3 April 2025
parents' body, only the germline. Germline mutations can occur before fertilization and during various stages of zygote development. When the mutation arises...
25 KB (3,085 words) - 03:46, 17 September 2024
separation of germ cells from somatic cells (germline development) occurs during early stages of development. Once this segregation has occurred in the...
18 KB (2,174 words) - 09:02, 31 August 2024
Abl Regulation of the mitotic/meiotic decision in the C. elegans germline development of alveoli in the lung. It has also been found that Rex1 has inhibitory...
95 KB (11,032 words) - 23:25, 20 February 2025
Germline mosaicism, also called gonadal mosaicism, is a type of genetic mosaicism where more than one set of genetic information is found specifically...
11 KB (1,435 words) - 08:27, 22 August 2024
Sengupta R, Zylicz JJ, Murakami K, Lee C, Down TA, Surani MA (January 2013). "Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine"...
28 KB (3,187 words) - 13:27, 27 March 2025
Weismann barrier (redirect from Soma-to-germline feedback)
Weismannist development (either preformistic or epigenetic) that in which there is a distinct germline, from somatic embryogenesis. This type of development is...
8 KB (867 words) - 08:37, 19 June 2024
Drosophila melanogaster male and female germline development. This structure has roles in maintaining germline cysts, coordinating the number of mitotic...
13 KB (1,722 words) - 00:04, 8 March 2025
Designer baby (section Human germline engineering)
widespread criticism and legal debates. This highlights the implications of germline engineering, which involves introducing the desired genetic material into...
78 KB (9,030 words) - 00:18, 29 April 2025
Piwi (section Role in germline cells)
mouse piwi). PIWI proteins play a crucial role in fertility and germline development across animals and ciliates. Recently identified as a polar granule...
17 KB (1,948 words) - 02:39, 25 December 2024
the production of most piRNAs in the germline and could also explain the origin of piRNAs in germline development. piRNAs were first observed in Drosophila...
7 KB (832 words) - 01:58, 1 December 2023
Development Growth & Differentiation is a peer-reviewed scientific journal published by Wiley on behalf of the Japanese Society of Developmental Biologists...
18 KB (293 words) - 13:56, 14 April 2025
1) is essential for chromatin silencing and germline development in Caenorhabditis elegans". Development. 128 (7): 1069–80. doi:10.1242/dev.128.7.1069...
20 KB (2,228 words) - 08:59, 26 March 2024
ovule. This role for sRNAs in plants resembles the role of piRNAs in germline development in Drosophila and some other animals. A similar phenomenon may also...
139 KB (14,822 words) - 02:25, 16 July 2024
Chimera (genetics) (redirect from Germline chimerism)
are passed to them because their mother retained them).[citation needed] Germline chimerism occurs when the germ cells (for example, sperm and egg cells)...
56 KB (6,402 words) - 14:00, 15 April 2025
Developmental biology (redirect from Biological development)
Sengupta R, Zylicz JJ, Murakami K, Lee C, Down TA, Surani MA (January 2013). "Germline DNA demethylation dynamics and imprint erasure through 5-hydroxymethylcytosine"...
38 KB (4,492 words) - 17:27, 24 March 2025
and Adrenal Gland cancers that it is known to cause. LFS is caused by germline mutations (also called genetic variants) in the TP53 tumor suppressor gene...
19 KB (2,097 words) - 04:08, 29 January 2025
Notch signaling pathways during hermaphrodite gonadal, vulval, and germline development. sel-12 also plays a role in thermotaxis (the nematode worm prefers...
1 KB (141 words) - 18:55, 11 September 2022
Mutation (section Germline mutation)
mutation in a parent. A germline mutation can be passed down through subsequent generations of organisms. The distinction between germline and somatic mutations...
119 KB (14,264 words) - 13:06, 16 April 2025
separation between sterile somatic cells and a germline are called Weismannists. Weismannist development is relatively rare (e.g., vertebrates, arthropods...
15 KB (1,793 words) - 21:47, 27 April 2025
Reinberg, D. (2016). "Co-repressor CBFA2T2 regulates pluripotency and germline development". Nature. 534 (7607): 387–390. Bibcode:2016Natur.534..387T. doi:10...
11 KB (1,318 words) - 12:33, 13 February 2024
MHC restriction (section Germline model)
models explaining how restriction arose are the germline model and the selection model. The germline model suggests that MHC restriction is a result of...
17 KB (2,241 words) - 23:15, 27 April 2025
esg is also expressed in expressed in germline stem cells and cyst stem cells of the testis and, during development, in neural stem cells and imaginal disks...
18 KB (2,000 words) - 20:29, 12 March 2025
Mosaic (genetics) (section Germline mosaicism)
mosaicism that occurs very early in the organisms development and thus is present within both germline and somatic cells. Somatic mosaicism is not generally...
23 KB (2,658 words) - 23:40, 28 December 2024
Miura T, Kobayashi T (1994). "The Onset of Spermatogenesis in Fish". Germline Development. Ciba Foundation Symposium. Vol. 182. pp. 255–67, discussion 267–70...
4 KB (245 words) - 09:57, 17 February 2024
Genetic engineering (redirect from Germline genome editing)
skin onto 80 percent of the boy's body which was affected by the illness. Germline gene therapy would result in any change being inheritable, which has raised...
135 KB (14,261 words) - 04:04, 30 April 2025
general body) and germline (sex cells and embryos for reproduction). The development of CRISPR gene editing enabled both somatic and germline editing (such...
120 KB (12,426 words) - 15:33, 30 April 2025