• growth factor is a naturally occurring substance capable of stimulating cell proliferation, wound healing, and occasionally cellular differentiation....
    10 KB (1,131 words) - 18:45, 6 May 2025
  • Thumbnail for Growth differentiation factor-9
    Growth/differentiation factor 9 is a protein that in humans is encoded by the GDF9 gene. Growth factors synthesized by ovarian somatic cells directly...
    27 KB (3,324 words) - 07:32, 29 January 2023
  • Growth differentiation factors (GDFs) are a subfamily of proteins belonging to the transforming growth factor beta superfamily that have functions predominantly...
    10 KB (1,271 words) - 15:32, 3 December 2023
  • Thumbnail for GDF15
    Growth/differentiation factor 15 is a protein that in humans is encoded by the GDF15 gene. GDF15 was first identified as Macrophage inhibitory cytokine-1...
    14 KB (1,444 words) - 05:06, 27 December 2024
  • Thumbnail for Epidermal growth factor
    Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
    17 KB (1,716 words) - 17:03, 24 April 2025
  • Thumbnail for Platelet-derived growth factor receptor
    PDGF subunits -A and -B are important factors regulating cell proliferation, cellular differentiation, cell growth, development and many diseases including...
    13 KB (1,563 words) - 09:00, 13 March 2024
  • (GDF8) Growth differentiation factor 9 (GDF9) Gyrification Neurogenesis Burgess WH, Maciag T (1989). "The heparin-binding (fibroblast) growth factor family...
    25 KB (3,126 words) - 10:38, 23 January 2025
  • Thumbnail for Leukemia inhibitory factor
    Leukemia inhibitory factor, or LIF, is an interleukin 6 class cytokine that affects cell growth by inhibiting differentiation. When LIF levels drop, the...
    13 KB (1,583 words) - 04:50, 17 August 2024
  • Thumbnail for Transforming growth factor beta
    Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different...
    67 KB (8,184 words) - 08:20, 28 December 2024
  • Thumbnail for Fibroblast growth factor receptor 2
    Fibroblast growth factor receptor 2 (FGFR-2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2...
    14 KB (1,745 words) - 09:02, 15 July 2024
  • regeneration, cell differentiation, embryonic development, and regulation of the immune system. Isoforms of transforming growth factor-beta (TGF-β1) are...
    6 KB (596 words) - 06:45, 1 January 2025
  • Thumbnail for Platelet-derived growth factor
    and differentiation, MSCs were shown to have stronger osteogenic differentiation into bone-forming cells when stimulated by epidermal growth factor (EGF)...
    24 KB (2,882 words) - 16:31, 25 October 2024
  • Thumbnail for Fibroblast growth factor 2
    Fibroblast growth factor 2 (FGF-2), also known as basic fibroblast growth factor (bFGF) and FGF-β, is a growth factor and signaling protein encoded by...
    22 KB (2,698 words) - 17:05, 16 July 2024
  • Thumbnail for Myostatin
    Myostatin (also known as growth differentiation factor 8, abbreviated GDF8) is a protein that in humans is encoded by the MSTN gene. Myostatin is a myokine...
    47 KB (5,232 words) - 20:08, 13 May 2025
  • Thumbnail for Epidermal growth factor receptor
    epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
    60 KB (6,879 words) - 01:06, 1 March 2025
  • Thumbnail for Insulin-like growth factor 1
    Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role...
    34 KB (4,512 words) - 06:26, 2 May 2025
  • is controversial. Nerve growth factor (NGF) uses the high-affinity receptor TrkA to promote myelination and the differentiation of neurons. Studies have...
    16 KB (1,784 words) - 04:08, 6 January 2024
  • Thumbnail for Kinase insert domain receptor
    type IV receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF receptor. KDR is the human gene encoding...
    6 KB (794 words) - 11:50, 18 May 2022
  • Thumbnail for Fibroblast growth factor receptor 3
    fibroblast growth factors, setting in motion a cascade of downstream signals which ultimately influence cell mitogenesis and differentiation. This particular...
    17 KB (1,844 words) - 17:02, 8 May 2025
  • Thumbnail for TGF alpha
    growth factor that is a ligand for the epidermal growth factor receptor, which activates a signaling pathway for cell proliferation, differentiation and...
    17 KB (2,112 words) - 08:28, 7 September 2024
  • Thumbnail for Platelet-derived growth factor receptor A
    Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded...
    29 KB (3,358 words) - 23:42, 16 March 2025
  • Thumbnail for Placental growth factor
    Placental growth factor (PlGF) is a protein that in humans is encoded by the PGF gene. Placental growth factor is a member of the VEGF (vascular endothelial...
    15 KB (1,867 words) - 09:38, 20 April 2025
  • Thumbnail for Nerve growth factor
    Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
    27 KB (3,110 words) - 09:14, 8 March 2025
  • Thumbnail for Brain-derived neurotrophic factor
    neurotrophic factor (BDNF), or abrineurin, is a protein that, in humans, is encoded by the BDNF gene. BDNF is a member of the neurotrophin family of growth factors...
    50 KB (5,881 words) - 13:31, 5 May 2025
  • Thumbnail for Neurotrophin
    belong to a class of growth factors, secreted proteins that can signal particular cells to survive, differentiate, or grow. Growth factors such as neurotrophins...
    28 KB (3,081 words) - 19:11, 28 November 2024
  • Thumbnail for Cellular differentiation
    and during normal cell turnover. Some differentiation occurs in response to antigen exposure. Differentiation dramatically changes a cell's size, shape...
    53 KB (6,222 words) - 21:54, 1 May 2025
  • Thumbnail for Fibroblast growth factor receptor 4
    designated as CD334 (cluster of differentiation 334). The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino...
    10 KB (1,291 words) - 09:08, 15 July 2024
  • Thumbnail for Hepatocyte growth factor
    Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells...
    23 KB (2,623 words) - 08:53, 15 March 2025
  • Thumbnail for TGF beta 1
    controls proliferation, differentiation, and other functions in many cell types. TGF-β acts synergistically with transforming growth factor-alpha (TGF-α) in...
    20 KB (2,309 words) - 20:56, 22 May 2025
  • Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
    40 KB (4,578 words) - 12:30, 10 September 2024