• Thumbnail for Insulin-like growth factor
    The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate...
    14 KB (1,689 words) - 01:31, 19 August 2024
  • Thumbnail for Insulin-like growth factor 1
    Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role...
    34 KB (4,517 words) - 04:19, 9 June 2025
  • Thumbnail for Insulin-like growth factor 2
    Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity to insulin. The MeSH definition reads: "A well-characterized...
    15 KB (1,901 words) - 19:51, 2 April 2025
  • Thumbnail for IGFBP3
    Insulin-like growth factor-binding protein 3, also known as IGFBP-3, is a protein that in humans is encoded by the IGFBP3 gene. IGFBP-3 is one of six...
    39 KB (4,717 words) - 13:09, 2 June 2024
  • Thumbnail for IGFBP7
    Insulin-like growth factor-binding protein 7 is a protein that in humans is encoded by the IGFBP7 gene. The major function of the protein is the regulation...
    20 KB (2,520 words) - 05:21, 20 May 2025
  • Thumbnail for Insulin-like growth factor-binding protein
    The insulin-like growth factor-binding protein (IGFBP) serves as a transport protein for insulin-like growth factor 1 (IGF-1). Approximately 98% of IGF-1...
    4 KB (468 words) - 09:09, 29 January 2023
  • Thumbnail for IGFALS
    Insulin-like growth factor binding protein, acid labile subunit, also known as IGFALS, is a protein which in humans is encoded by the IGFALS gene. The...
    9 KB (1,079 words) - 11:00, 21 February 2024
  • Thumbnail for Fibroblast growth factor 2
    (FGF2); Heparin-binding growth factor-2; and Endothelial cell growth factor-2. Gene sequencing revealed that this group is the same FGF2 protein and is a member...
    22 KB (2,698 words) - 15:56, 25 May 2025
  • Artemin Growth differentiation factor-9 (GDF9) Hepatocyte growth factor (HGF) Hepatoma-derived growth factor (HDGF) Insulin Insulin-like growth factors Insulin-like...
    10 KB (1,131 words) - 18:45, 6 May 2025
  • known as pregnancy-associated plasma protein A, and insulin-like growth factor binding protein-4 protease is a protein encoded by the PAPPA gene in humans...
    5 KB (562 words) - 10:00, 27 March 2024
  • Thumbnail for IGFBP1
    Insulin-like growth factor-binding protein 1 (IBP-1) also known as placental protein 12 (PP12) is a protein that in humans is encoded by the IGFBP1 gene...
    8 KB (1,045 words) - 09:28, 13 August 2023
  • Androgen-binding protein Maltose-binding protein Phosphatidylethanolamine binding protein 1 Syntaxin binding protein 3 Insulin-like growth factor-binding protein...
    2 KB (263 words) - 21:49, 28 December 2020
  • Thumbnail for Insulin-like growth factor 1 receptor
    The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by...
    29 KB (3,603 words) - 16:26, 25 May 2024
  • Thumbnail for Transferrin
    2001). "Transferrin binds insulin-like growth factors and affects binding properties of insulin-like growth factor binding protein-3". FEBS Letters. 509 (3):...
    24 KB (2,777 words) - 16:43, 9 October 2024
  • IGF-1 LR3 (category Insulin-like growth factor receptor agonists)
    as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). It differs from native IGF-1 in...
    5 KB (412 words) - 23:17, 19 June 2023
  • Thumbnail for Forkhead box protein O1
    serine 256 by protein kinase B disrupts transactivation by FKHR and mediates effects of insulin on insulin-like growth factor-binding protein-1 promoter...
    28 KB (3,343 words) - 16:25, 12 April 2025
  • Thumbnail for Heparin-binding EGF-like growth factor
    Heparin-binding EGF-like growth factor (HB-EGF) is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. HB-EGF-like growth factor...
    20 KB (2,598 words) - 14:07, 21 July 2024
  • activity of imaginal morphogenesis protein-late 2 (ImpL2) (fly homolog of mammalian insulin-like growth factor binding protein IGFBP7), which is required to...
    18 KB (2,000 words) - 03:50, 9 June 2025
  • Thumbnail for Acanthosis nigricans
    particularly IGF-1. At high concentrations, insulin may also displace IGF-1 from insulin-like growth factor-binding protein (IGFBP). Increased circulating IGF...
    18 KB (1,783 words) - 11:16, 19 April 2025
  • Thumbnail for Epidermal growth factor
    Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
    17 KB (1,716 words) - 11:48, 25 May 2025
  • Thumbnail for CTGF
    domains. These domains are, from N- to C-termini, the insulin-like growth factor binding protein (IGFBP) domain, the von Willebrand type C repeats (vWC)...
    13 KB (1,537 words) - 17:37, 27 December 2023
  • insulin-like growth factors I and II, insulin-like growth factor binding protein-3 and epidermal growth factor on human breast epithelial cells in primary...
    59 KB (6,495 words) - 19:13, 23 May 2025
  • Mecasermin (category Insulin-like growth factor receptor agonists)
    of mecasermin (rhIGF-1), insulin-like growth factor binding protein-3 (IGFBP-3), and insulin-like growth factor binding protein acid labile subunit (IGFALS)...
    5 KB (311 words) - 17:08, 11 April 2025
  • Thumbnail for Insulin receptor
    1997). "Human GRB-IRbeta/GRB10. Splice variants of an insulin and growth factor receptor-binding protein with PH and SH2 domains". The Journal of Biological...
    32 KB (3,920 words) - 18:44, 1 May 2025
  • Thumbnail for Fibroblast growth factor 21
    Fibroblast growth factor 21 (FGF-21) is a protein that in mammals is encoded by the FGF21 gene. The protein encoded by this gene is a member of the fibroblast...
    24 KB (3,038 words) - 23:40, 29 November 2024
  • growth factor 2 receptor (IGF-2R) Insulin-like growth factor Insulin-like growth factor 1 Insulin-like growth factor 2 Insulin-like growth factor-binding protein...
    608 bytes (51 words) - 12:36, 21 February 2022
  • Thumbnail for Insulin-like growth factor 2 receptor
    Insulin-like growth factor 2 receptor (IGF2R), also called the cation-independent mannose-6-phosphate receptor (CI-MPR) is a protein that in humans is...
    13 KB (1,664 words) - 16:27, 25 May 2024
  • Thumbnail for Sex hormone-binding globulin
    as a hepatokine. It decreases with high levels of insulin, growth hormone, insulin-like growth factor 1 (IGF-1), androgens, prolactin and transcortin....
    57 KB (4,574 words) - 00:37, 18 December 2024
  • Frohman LA (March 2006). "Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing...
    12 KB (1,289 words) - 21:00, 29 May 2025
  • Neurotrophic factors (NTFs) are a family of biomolecules – nearly all of which are peptides or small proteins – that support the growth, survival, and...
    16 KB (1,784 words) - 04:08, 6 January 2024