• Thumbnail for Interferon-gamma receptor
    The interferon-gamma receptor (IFNGR) protein complex is the heterodimer of two chains: IFNGR1 and IFNGR2. It binds interferon-γ, the sole member of interferon...
    8 KB (870 words) - 23:14, 28 May 2024
  • Thumbnail for Interferon gamma receptor 2
    Interferon gamma receptor 2 also known as IFN-γR2 is a protein which in humans is encoded by the IFNGR2 gene. This gene (IFNGR2) encodes the non-ligand-binding...
    2 KB (245 words) - 00:15, 8 October 2023
  • Thumbnail for Interferon gamma
    heterodimeric receptor consisting of Interferon gamma receptor 1 (IFNGR1) and Interferon gamma receptor 2 (IFNGR2). IFN-γ binding to the receptor activates...
    56 KB (6,483 words) - 16:47, 27 December 2024
  • Thumbnail for Interferon
    Based on the type of receptor through which they signal, human interferons have been classified into three major types. Interferon type I: All type I IFNs...
    62 KB (7,124 words) - 12:38, 5 April 2025
  • Thumbnail for Interferon gamma receptor 1
    Interferon gamma receptor 1 (IFNGR1) also known as CD119 (Cluster of Differentiation 119), is a protein that in humans is encoded by the IFNGR1 gene....
    12 KB (1,390 words) - 22:37, 2 April 2024
  • Thumbnail for Interferon-alpha/beta receptor
    The interferon-α/β receptor (IFNAR) is a virtually ubiquitous membrane receptor which binds endogenous type I interferon (IFN) cytokines. Endogenous human...
    24 KB (2,617 words) - 19:43, 7 August 2022
  • complete deficiency in the interferon-gamma receptor have significant elevations in plasma concentrations of interferon-gamma, which can be measured by...
    14 KB (1,413 words) - 18:38, 25 May 2025
  • Thumbnail for Chromosome 21
    IFNAR1: encoding interferon alpha/beta receptor 1 IFNAR2: encoding interferon alpha/beta receptor 2 IFNGR2: encoding interferon gamma receptor 2 IL10RB: encoding...
    33 KB (3,073 words) - 20:08, 15 March 2025
  • problems. Interleukin 12 receptor, beta 1 deficiency IL-12p40 deficiency Interferon gamma receptor 1 deficiency Interferon gamma receptor 2 deficiency Tyk2 deficiency...
    19 KB (1,853 words) - 07:31, 11 May 2025
  • Thumbnail for Peroxisome proliferator-activated receptor gamma
    proliferator-activated receptor gamma (PPAR-γ or PPARG), also known as the glitazone reverse insulin resistance receptor, or NR1C3 (nuclear receptor subfamily 1...
    19 KB (2,091 words) - 16:26, 26 May 2025
  • Thumbnail for Retinoid X receptor gamma
    Retinoid X receptor gamma (RXR-gamma), also known as NR2B3 (nuclear receptor subfamily 2, group B, member 3) is a nuclear receptor that in humans is encoded...
    9 KB (1,087 words) - 17:49, 3 December 2023
  • interferon-alpha/beta receptor interferon-gamma receptor Interferon type III receptor Interleukin-10 receptor Interleukin-20 receptor Interleukin-22 receptor Interleukin-28...
    6 KB (616 words) - 00:02, 30 March 2025
  • Thumbnail for IL-2 receptor
    IL-2Rβ, or CD122), and γ (gamma) (also called IL-2Rγ, γc, common gamma chain, or CD132); these subunits are also parts of receptors for other cytokines.: 713 ...
    9 KB (934 words) - 16:50, 3 October 2024
  • Thumbnail for Interferon type I
    pseudogenes. Interferons bind to interferon receptors. All type I IFNs bind to a specific cell surface receptor complex known as the IFN-α receptor (IFNAR)...
    24 KB (2,934 words) - 22:15, 24 May 2025
  • Thumbnail for Retinoic acid receptor gamma
    Retinoic acid receptor gamma (RAR-γ), also known as NR1B3 (nuclear receptor subfamily 1, group B, member 3) is a nuclear receptor encoded by the RARG...
    10 KB (1,208 words) - 06:34, 8 November 2023
  • Thumbnail for Estrogen-related receptor gamma
    Estrogen-related receptor gamma (ERR-gamma), also known as NR3B3 (nuclear receptor subfamily 3, group B, member 3), is a nuclear receptor that in humans...
    10 KB (1,243 words) - 09:39, 12 October 2023
  • Thumbnail for Interleukin 12
    the growth and function of T cells. It stimulates the production of interferon-gamma (IFN-γ) and tumor necrosis factor-alpha (TNF-α) from T cells and natural...
    14 KB (1,578 words) - 17:58, 24 May 2025
  • responses to some cytokines, such as interferon-gamma. JAK1 and JAK2 are involved in type II interferon (interferon-gamma) signalling, whereas JAK1 and TYK2...
    9 KB (974 words) - 14:46, 22 June 2024
  • Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the...
    7 KB (672 words) - 21:11, 29 May 2025
  • Thumbnail for Interferon beta-1a
    Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian...
    32 KB (2,851 words) - 23:22, 16 August 2024
  • different receptors within this receptor family. The IL-2 receptor common gamma chain (also known as CD132) is shared between: IL-2 receptor IL-4 receptor IL-7...
    5 KB (514 words) - 21:40, 3 October 2024
  • Interleukin-28 receptor is a type II cytokine receptor found largely in epithelial cells. It binds type 3 interferons, interleukin-28 A (Interferon lambda 1)...
    10 KB (1,126 words) - 20:57, 24 June 2021
  • Thumbnail for Cytokine
    Cytokine (section Receptors)
    cytokines by topology. Some members share the common gamma chain as part of their receptor. the interferon (IFN) subfamily. the IL-10 subfamily. The IL-1 family...
    37 KB (4,169 words) - 17:17, 23 May 2025
  • Thumbnail for Peroxisome proliferator-activated receptor
    Belfiore A, Genua M, Malaguarnera R (2009). "PPAR-gamma Agonists and Their Effects on IGF-I Receptor Signaling: Implications for Cancer". PPAR Res. 2009:...
    18 KB (1,885 words) - 06:27, 15 April 2025
  • Thumbnail for Murine respirovirus
    by synergistic action of gamma-irradiation and DCs treated with rSeV expressing interferon-beta gene". Gene Therapy. 16 (2): 240–51. doi:10.1038/gt.2008...
    297 KB (32,094 words) - 15:13, 22 May 2025
  • Thumbnail for Cell-mediated immunity
    chemokines CXCL9, CXCL10 and CXCL11 in response to interferon gamma. Additionally, interferon gamma secreted by these cells seems to be important in downregulating...
    14 KB (1,377 words) - 23:44, 25 May 2025
  • hormone receptor is a receptor molecule that binds to a specific hormone. Hormone receptors are a wide family of proteins made up of receptors for thyroid...
    17 KB (2,015 words) - 03:11, 30 January 2025
  • Thumbnail for Interleukin-1 receptor antagonist
    (March 2023). "Tumour necrosis factor alpha, interleukin 1 beta and interferon gamma have detrimental effects on equine tenocytes that cannot be rescued...
    12 KB (1,323 words) - 14:55, 7 September 2024
  • Thumbnail for Interleukin-7 receptor
    the accessibility of a region of the genome that contains the T-cell receptor gamma gene, by STAT5 and histone acetylation [citation needed]. Knockout studies...
    6 KB (550 words) - 00:43, 19 August 2023
  • T-cells. As a result of active transcription of the interferon gamma (IFN-gamma) gene by T-bet, IFN-gamma levels are increased, which reduces colony formation...
    41 KB (4,374 words) - 11:56, 16 April 2025