• Thumbnail for Kinase insert domain receptor
    Kinase insert domain receptor (KDR, a type IV receptor tyrosine kinase) also known as vascular endothelial growth factor receptor 2 (VEGFR-2) is a VEGF...
    6 KB (794 words) - 11:50, 18 May 2022
  • Thumbnail for Platelet-derived growth factor receptor
    been identified in the juxtamembrane domain, the kinase insert, and in the C-terminal tail in the PDGFβ receptor. The phosphorylated tyrosine residue...
    13 KB (1,563 words) - 09:00, 13 March 2024
  • Thumbnail for Insulin receptor
    insulin receptor (IR) is a transmembrane receptor that is activated by insulin, IGF-I, IGF-II and belongs to the large class of receptor tyrosine kinase. Metabolically...
    31 KB (3,785 words) - 05:54, 22 April 2024
  • Thumbnail for VEGF receptor
    tyrosine kinase receptors (the VEGFRs) on the cell surface, causing them to dimerize and become activated through transphosphorylation. The VEGF receptors have...
    8 KB (755 words) - 18:51, 2 November 2023
  • Thumbnail for Endometriosis
    including the mitogen activated protein (MAP) kinase pathway and the extracellular signal-related kinase (ERK) pathway. Activation of both of the MAP and...
    157 KB (16,275 words) - 19:48, 22 May 2024
  • Thumbnail for Tropomyosin receptor kinase C
    Tropomyosin receptor kinase C (TrkC), also known as NT-3 growth factor receptor, neurotrophic tyrosine kinase receptor type 3, or TrkC tyrosine kinase is a protein...
    32 KB (3,936 words) - 03:00, 29 January 2024
  • kinase-1 (flt-1) was shown to be a VEGF receptor by Ferrara et al. in 1992. The kinase insert domain receptor (KDR) was shown to be a VEGF receptor by...
    40 KB (4,578 words) - 20:20, 10 March 2024
  • VEGFR-2 inhibitor (category Tyrosine kinase inhibitors)
    VEGFR-2 inhibitor, also known as kinase insert domain receptor(KDR) inhibitor, are tyrosine kinase receptor inhibitors that reduce angiogenesis or lymphangiogenesis...
    51 KB (4,735 words) - 08:15, 2 January 2024
  • endothelial growth factor receptor 2/kinase insert domain receptor (VEGFR2/KDR), and transmembrane protein 163 (TMEM163) receptors. Rubin H. (2008) Contact...
    2 KB (201 words) - 23:45, 12 October 2018
  • Thumbnail for Annexin A5
    fluorescence microscope. Annexin A5 has been shown to interact with Kinase insert domain receptor and Integrin, beta 5. GRCh38: Ensembl release 89: ENSG00000164111...
    13 KB (1,645 words) - 00:29, 11 March 2024
  • college fraternity The ISO 639-3 code for the Karaim language Kinase insert domain receptor, a human protein Short distance radio or KDR 444, Norway and...
    862 bytes (114 words) - 23:29, 30 March 2024
  • Thumbnail for AMPA receptor
    Copenhagen. The GRIA2-encoded AMPA receptor ligand binding core (GluA2 LBD) was the first glutamate receptor ion channel domain to be crystallized. AMPARs are...
    60 KB (7,019 words) - 07:40, 8 May 2024
  • Thumbnail for Hepatocyte growth factor receptor
    Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity. The primary...
    58 KB (6,923 words) - 01:30, 3 May 2024
  • Thumbnail for CD135
    tyrosine-kinase insert. Cytoplasmic FLT3 undergoes glycosylation, which promotes localization of the receptor to the membrane. CD135 is a class III receptor tyrosine...
    15 KB (1,728 words) - 08:50, 15 December 2023
  • Thumbnail for NMDA receptor
    receptor (also known as the NMDA receptor or NMDAR), is a glutamate receptor and predominantly Ca2+ ion channel found in neurons. The NMDA receptor is...
    107 KB (12,051 words) - 23:49, 26 April 2024
  • A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of protein kinase that is specific to the amino acids serine and threonine (i.e., a...
    46 KB (5,509 words) - 06:42, 23 May 2024
  • the kinase domain do not involve important domain-domain contacts away from the substrate binding site. Among a number of various molecules, Receptor Tyrosine...
    19 KB (2,321 words) - 21:42, 5 January 2024
  • Thumbnail for SHC2
    encoded by the SHC2 gene. SHC2 has been shown to interact with Kinase insert domain receptor. GRCh38: Ensembl release 89: ENSG00000129946 – Ensembl, May...
    4 KB (449 words) - 01:52, 17 April 2022
  • Thumbnail for Signal transduction
    by protein kinases, ultimately resulting in a cellular response. Proteins responsible for detecting stimuli are generally termed receptors, although in...
    63 KB (7,624 words) - 03:29, 26 January 2024
  • Thumbnail for KIT (gene)
    Proto-oncogene c-KIT is the gene encoding the receptor tyrosine kinase protein known as tyrosine-protein kinase KIT, CD117 (cluster of differentiation 117)...
    35 KB (4,118 words) - 18:22, 5 January 2024
  • Thumbnail for Integrin
    Integrin (redirect from Integrin receptor)
    transmembrane protein kinases such as receptor tyrosine kinases (RTK). While the interaction between integrin and receptor tyrosine kinases originally was thought...
    36 KB (3,929 words) - 08:32, 12 May 2024
  • Thumbnail for Colony stimulating factor 1 receptor
    cytoplasmic domain has a juxtamembrane domain and tyrosine kinase domain that is interrupted by a kinase insert domain. At rest, the juxtamembrane domain of CSF1R...
    44 KB (4,593 words) - 17:52, 18 April 2024
  • endothelial associated proteins, such as VE-cadherin and kinase insert domain receptor (KDR, VEGF receptor 2) which aid in influencing the progression of angiogenesis...
    50 KB (5,423 words) - 11:11, 28 March 2024
  • Thumbnail for Chromosome 4
    INTS12: Integrator complex subunit 12 KDR: Kinase insert domain receptor (Vascular endothelial growth factor receptor 2) KIAA1530: UV stimulated scaffold protein...
    31 KB (1,913 words) - 03:37, 10 March 2024
  • Thumbnail for Low-density lipoprotein receptor-related protein 8
    activation of Src family kinases, which have been shown to play a role in regulating synaptic plasticity. VLDLR also acts as a receptor coupled to ApoER2 as...
    27 KB (3,439 words) - 10:00, 27 March 2024
  • chimeric antigen receptors (CARs)—also known as chimeric immunoreceptors, chimeric T cell receptors or artificial T cell receptors—are receptor proteins that...
    75 KB (7,889 words) - 06:29, 20 May 2024
  • Thumbnail for GRB2
    growth factor receptor tyrosine kinase to the activation of Ras and its downstream kinases, ERK1,2. Grb2 is composed of an SH2 domain flanked on each...
    82 KB (9,365 words) - 15:39, 31 March 2024
  • Thumbnail for Sema domain
    repellent signals during axon guidance. Sema domains also occur in the hepatocyte growth factor receptor (Uniprot: P08581), Plexin-A3 (Uniprot: P51805)...
    4 KB (520 words) - 19:02, 6 July 2021
  • Thumbnail for PDGFRB
    PDGFRB (category Tyrosine kinase receptors)
    The PDGFRB gene encodes a typical receptor tyrosine kinase, which belongs to the type III tyrosine kinase receptor (RTK) family and is structurally characterized...
    31 KB (3,403 words) - 18:14, 24 December 2023
  • Thumbnail for PTPN11
    Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) also known as protein-tyrosine phosphatase 1D (PTP-1D), Src homology region 2 domain-containing phosphatase-2...
    37 KB (4,300 words) - 06:32, 13 March 2024