immunology, a linear epitope (also sequential epitope) is an epitope—a binding site on an antigen—that is recognized by antibodies by its linear sequence of...

diseases) are also epitopes. The epitopes of protein antigens are divided into two categories, conformational epitopes and linear epitopes, based on their...

and/or structural data. Epitopes are generally divided into two classes: linear and conformational/discontinuous. Linear epitopes are formed by a continuous...

line. These are known as linear epitopes. Antigen Linear epitope Epitope mapping, finding (on an antigen protein) the epitope(s) for a specific antibody...

adaptive immunity. Antigenic escape Antitoxin Conformational epitope Epitope Linear epitope Magnetic immunoassay Neutralizing antibody Original antigenic...

cell), this explanation is too simplistic. Such epitopes are known as sequential or linear epitopes, as all the amino acids on them are in the same sequence...

body). The TCRs of T lymphocytes recognise only sequential epitopes, also called linear epitopes, of only peptides and only if coupled within an MHC molecule...

broken down into pieces in both of these antigens. Less commonly, the NC16a epitope on BP180 has been linked to LABD. IgA antibodies directed against various...

to conformational epitopes of the immunogenic carboxyl-terminal region of the TPO protein, although antibodies to linear epitopes have been seen. Anti-TPO...

leukotriene-B4 20-monooxygenase - library - licodione synthase - ligase - linear epitope - linkage - linker protein - linoleate diol synthase - lipofectin -...

M; Sakarellos, C; Moutsopoulos, H M (1998). "The value of synthetic linear epitope analogues of La/SSB for the detection of autoantibodies to La/SSB; specificity...

Further studies have expanded the ideal epitope beyond ELDKWAS and revealed that the extended linear epitope NEQELLELDKWASLWN increased 2F5 affinity greatly...

Schäfer C, Schneider C, Bautz FA (1999). "Identification of major linear epitopes on the sp100 nuclear PBC autoantigen by the gene-fragment phage-display...

allergoid sustain the linear epitopes recognized by the MHC-TCR cell-present systems (keeps the immunoreactivity) but has less reaginic epitopes (less allergenicity)...

cells require antigens to be processed into short fragments which form linear epitopes on MHC Class II (in the case of helper T cells because they express...

Silva Menegasso AR, Pêgo PN, Santos KS, et al. (January 2015). "B-cell linear epitopes mapping of antigen-5 allergen from Polybia paulista wasp venom". The...

peptides that have been shown in several publications to contain human linear B cell epitopes in spike protein of SARS-CoV-2. Moreover, the study was criticized...

their protein products. Either the linear amino acid sequence or the conformational fit of the immunodominant epitope may be shared between the pathogen...

epitopes, antibodies have gained interest in both basic and clinical research. The foundation of antibody characterization and validation is epitope mapping...

differentiation into plasma cells and proliferation T cell receptors Linear epitopes bound to MHC Activate T cells Cytokine receptors Cytokines Regulation...

Steve; Gilbert, Peter; Montefiori, David C. (2013). "Plasma IgG to linear epitopes in the V2 and V3 regions of HIV-1 gp120 correlate with a reduced risk...

transports digested viral antigen epitope peptides from the cytosol to the endoplasmic reticulum, allowing these epitopes to be combined with MHC class I...

factor receptor Leukocyte extravasation Leukocyte-promoting factor Linear epitope Lipid A Lipopolysaccharide binding protein Low-affinity nerve growth...

how much antibody an organism has produced that recognizes a particular epitope. It is conventionally expressed as the inverse of the greatest dilution...

Petersen G, Song D, Hugle-Dorr B, Oldenburg I, Bautz EK: Mapping of linear epitopes recognized by monoclonal antibodies with gene-fragment phage display...

genus Iris FLAG (chemotherapy), a chemotherapy regimen FLAG-tag, a unique epitope added to proteins in biochemistry Flagging (botany), a growth pattern that...

KARR-ə-GHEE-nənz; from Irish carraigín 'little rock') are a family of natural linear sulfated polysaccharides. They are extracted from red edible seaweeds. Carrageenans...

region. This is thought to allow IgA1 to adapt more effectively to varying epitope spacings on multivalent antigens, while also presenting less resistance...

A peptide microarray (also commonly known as peptide chip or peptide epitope microarray) is a collection of peptides displayed on a solid surface, usually...

Galili, U (February 2008). "The Galalpha1,3Galbeta1,4GlcNAc-R (alpha-Gal) epitope: a carbohydrate of unique evolution and clinical relevance". Biochimica...