Monoamine transporters (MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine...
21 KB (2,342 words) - 15:34, 14 September 2024
The vesicular monoamine transporter (VMAT) is a transport protein integrated into the membranes of synaptic vesicles of presynaptic neurons. It transports...
43 KB (4,993 words) - 04:26, 10 March 2025
solute carrier family 18 member 2 (SLC18A2) also known as vesicular monoamine transporter 2 (VMAT2) is a protein that in humans is encoded by the SLC18A2...
29 KB (3,347 words) - 14:46, 25 May 2025
Monoamine reuptake inhibitor Monoamine receptor Monoamine oxidase Monoamine transporter Monoamine Hypothesis Biogenic amine Trace amine Monoamine nuclei...
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of the monoamine transporters (MATs), including the serotonin transporter (SERT), norepinephrine transporter (NET), and/or dopamine transporter (DAT),...
262 KB (22,099 words) - 16:54, 8 June 2025
The plasma membrane monoamine transporter (PMAT) is a low-affinity monoamine transporter protein which in humans is encoded by the SLC29A4 gene. It is...
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respective monoamine transporters (MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT)...
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widely accepted model for monoamine transporter function, sodium ions must bind to the extracellular domain of the transporter before dopamine can bind...
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by the solute carrier family 6 member 2 (SLC6A2) gene. NET is a monoamine transporter and is responsible for the sodium-chloride (Na+/Cl−)-dependent reuptake...
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that in humans is encoded by the SLC6A4 gene. SERT is a type of monoamine transporter protein that transports the neurotransmitter serotonin from the...
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Reuptake inhibitor (redirect from Non-selective monoamine reuptake inhibitors)
triethylcholine Vesicular acetylcholine transporter (VAChT) inhibitor – vesamicol Vesicular monoamine transporter (VMAT) inhibitor – reserpine, tetrabenazine...
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Phenethylamine (section Monoamine releasing agent)
amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons. To a lesser extent, it also acts as a neurotransmitter...
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Vesicular monoamine transporter 1 (VMAT1), also known as chromaffin granule amine transporter (CGAT) or solute carrier family 18 member 1 (SLC18A1), is...
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the cellular monoamine transporter, especially the dopamine transporter (DAT) and less so the norepinephrine (NET) and serotonin transporter. The mechanism...
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Reverse transport (redirect from Transporter reversal)
the synaptic cleft via monoamine transporter-mediated release) by triggering reverse transport at vesicular monoamine transporters (specifically, VMAT1...
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reuptake of these monoamine neurotransmitters through the simultaneous inhibition of the serotonin transporter (SERT), norepinephrine transporter (NET), and...
142 KB (16,594 words) - 16:53, 5 June 2025
Phentermine (section Monoamine releasing agent)
phentermine. Phentermine is a substrate of the monoamine transporters (MATs) and acts as a monoamine releasing agent (MRA), specifically as a norepinephrine–dopamine...
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Membrane transport protein (redirect from Membrane transporter)
amino acid transporters (EAATs) EAAT1 EAAT2 EAAT3 EAAT4 EAAT5 Glucose transporter Monoamine transporters, including: Dopamine transporter (DAT) Norepinephrine...
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PMID 14612135. Rothman RB, Baumann MH (2006). "Therapeutic potential of monoamine transporter substrates". Curr Top Med Chem. 6 (17): 1845–1859. doi:10.2174/156802606778249766...
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Dopamine reuptake inhibitor (redirect from Dopamine transporter "inverse agonist")
as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved...
19 KB (1,930 words) - 22:33, 23 May 2025
monoamine transporters (i.e., the dopamine transporter, norepinephrine transporter, or serotonin transporter) to either stop transporting monoamines altogether...
63 KB (22,935 words) - 16:22, 9 June 2025
inhibition of the serotonin transporter and PDE4. It promotes monoamine release through vesicular monoamine transporter-2 upregulation, with serotonin...
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SLC22A3 (redirect from Extraneuronal monoamine transporter)
3 (SLC22A3) also known as the organic cation transporter 3 (OCT3) or extraneuronal monoamine transporter (EMT) is a protein that in humans is encoded...
11 KB (1,306 words) - 03:55, 11 January 2025
substituted cathinone family. 3-MMC is a monoamine transporter substrate (a substance acted upon by monoamine transporters in the brain) that potently releases...
25 KB (2,411 words) - 21:03, 2 June 2025
interact with monoamine transporters, in particular the dopamine transporter (DAT), norepinephrine transporter (NET), and serotonin transporter (SERT). The...
18 KB (1,936 words) - 08:40, 12 March 2025
changes in brain monoamine levels, some others suggested a rapid reduction in serotonin transporter (SERT) and dopamine transporter (DAT) function. Persistent...
143 KB (13,691 words) - 15:20, 3 June 2025
transporters. Other transporters that methamphetamine is known to inhibit are SLC22A3 and SLC22A5. SLC22A3 is an extraneuronal monoamine transporter that...
170 KB (16,612 words) - 21:29, 29 May 2025
Valbenazine (category Monoamine-depleting agents)
medication used to treat tardive dyskinesia. It acts as a vesicular monoamine transporter 2 (VMAT2) inhibitor. Valbenazine is used to treat tardive dyskinesia...
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dopamine transporter or by the plasma membrane monoamine transporter. Once back in the cytosol, dopamine can either be broken down by a monoamine oxidase...
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influenced by heredity and that a specific gene, called vesicular monoamine transporter 2 (VMAT2), predisposes humans towards spiritual or mystic experiences...
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