• Thumbnail for Monoamine transporter
    Monoamine transporters (MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine...
    21 KB (2,342 words) - 15:34, 14 September 2024
  • The vesicular monoamine transporter (VMAT) is a transport protein integrated into the membranes of synaptic vesicles of presynaptic neurons. It transports...
    43 KB (4,993 words) - 04:26, 10 March 2025
  • Thumbnail for Vesicular monoamine transporter 2
    solute carrier family 18 member 2 (SLC18A2) also known as vesicular monoamine transporter 2 (VMAT2) is a protein that in humans is encoded by the SLC18A2...
    29 KB (3,347 words) - 14:46, 25 May 2025
  • Thumbnail for Monoamine neurotransmitter
    Monoamine reuptake inhibitor Monoamine receptor Monoamine oxidase Monoamine transporter Monoamine Hypothesis Biogenic amine Trace amine Monoamine nuclei...
    7 KB (1,409 words) - 21:17, 11 March 2024
  • Thumbnail for Monoamine releasing agent
    of the monoamine transporters (MATs), including the serotonin transporter (SERT), norepinephrine transporter (NET), and/or dopamine transporter (DAT),...
    262 KB (22,099 words) - 16:54, 8 June 2025
  • Thumbnail for Plasma membrane monoamine transporter
    The plasma membrane monoamine transporter (PMAT) is a low-affinity monoamine transporter protein which in humans is encoded by the SLC29A4 gene. It is...
    13 KB (1,444 words) - 17:18, 12 June 2025
  • Thumbnail for Monoamine reuptake inhibitor
    respective monoamine transporters (MATs), which include the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT)...
    20 KB (1,388 words) - 21:36, 30 January 2025
  • Thumbnail for Dopamine transporter
    widely accepted model for monoamine transporter function, sodium ions must bind to the extracellular domain of the transporter before dopamine can bind...
    84 KB (9,204 words) - 02:53, 2 June 2025
  • Thumbnail for Norepinephrine transporter
    by the solute carrier family 6 member 2 (SLC6A2) gene. NET is a monoamine transporter and is responsible for the sodium-chloride (Na+/Cl−)-dependent reuptake...
    33 KB (3,478 words) - 15:43, 11 January 2025
  • Thumbnail for Serotonin transporter
    that in humans is encoded by the SLC6A4 gene. SERT is a type of monoamine transporter protein that transports the neurotransmitter serotonin from the...
    31 KB (3,442 words) - 04:14, 20 May 2025
  • Thumbnail for Reuptake inhibitor
    triethylcholine Vesicular acetylcholine transporter (VAChT) inhibitor – vesamicol Vesicular monoamine transporter (VMAT) inhibitor – reserpine, tetrabenazine...
    19 KB (1,917 words) - 07:07, 23 November 2024
  • Thumbnail for Phenethylamine
    amine-associated receptor 1 (TAAR1) and inhibiting vesicular monoamine transporter 2 (VMAT2) in monoamine neurons. To a lesser extent, it also acts as a neurotransmitter...
    56 KB (5,429 words) - 10:45, 2 June 2025
  • Thumbnail for Vesicular monoamine transporter 1
    Vesicular monoamine transporter 1 (VMAT1), also known as chromaffin granule amine transporter (CGAT) or solute carrier family 18 member 1 (SLC18A1), is...
    16 KB (1,962 words) - 20:13, 1 May 2025
  • Thumbnail for Amphetamine
    the cellular monoamine transporter, especially the dopamine transporter (DAT) and less so the norepinephrine (NET) and serotonin transporter. The mechanism...
    310 KB (32,749 words) - 13:19, 11 June 2025
  • the synaptic cleft via monoamine transporter-mediated release) by triggering reverse transport at vesicular monoamine transporters (specifically, VMAT1...
    7 KB (744 words) - 09:34, 10 January 2025
  • reuptake of these monoamine neurotransmitters through the simultaneous inhibition of the serotonin transporter (SERT), norepinephrine transporter (NET), and...
    142 KB (16,594 words) - 16:53, 5 June 2025
  • Thumbnail for Phentermine
    phentermine. Phentermine is a substrate of the monoamine transporters (MATs) and acts as a monoamine releasing agent (MRA), specifically as a norepinephrine–dopamine...
    44 KB (4,028 words) - 15:33, 30 May 2025
  • amino acid transporters (EAATs) EAAT1 EAAT2 EAAT3 EAAT4 EAAT5 Glucose transporter Monoamine transporters, including: Dopamine transporter (DAT) Norepinephrine...
    26 KB (2,656 words) - 14:08, 8 March 2025
  • Thumbnail for Substituted cathinone
    PMID 14612135. Rothman RB, Baumann MH (2006). "Therapeutic potential of monoamine transporter substrates". Curr Top Med Chem. 6 (17): 1845–1859. doi:10.2174/156802606778249766...
    95 KB (4,192 words) - 05:13, 11 May 2025
  • as a reuptake inhibitor of the monoamine neurotransmitter dopamine by blocking the action of the dopamine transporter (DAT). Reuptake inhibition is achieved...
    19 KB (1,930 words) - 22:33, 23 May 2025
  • Thumbnail for Adderall
    monoamine transporters (i.e., the dopamine transporter, norepinephrine transporter, or serotonin transporter) to either stop transporting monoamines altogether...
    63 KB (22,935 words) - 16:22, 9 June 2025
  • Thumbnail for Mesembryanthemum tortuosum
    inhibition of the serotonin transporter and PDE4. It promotes monoamine release through vesicular monoamine transporter-2 upregulation, with serotonin...
    20 KB (2,126 words) - 10:15, 7 June 2025
  • Thumbnail for SLC22A3
    3 (SLC22A3) also known as the organic cation transporter 3 (OCT3) or extraneuronal monoamine transporter (EMT) is a protein that in humans is encoded...
    11 KB (1,306 words) - 03:55, 11 January 2025
  • Thumbnail for 3-Methylmethcathinone
    substituted cathinone family. 3-MMC is a monoamine transporter substrate (a substance acted upon by monoamine transporters in the brain) that potently releases...
    25 KB (2,411 words) - 21:03, 2 June 2025
  • Thumbnail for 3-Chloromethcathinone
    interact with monoamine transporters, in particular the dopamine transporter (DAT), norepinephrine transporter (NET), and serotonin transporter (SERT). The...
    18 KB (1,936 words) - 08:40, 12 March 2025
  • Thumbnail for Mephedrone
    changes in brain monoamine levels, some others suggested a rapid reduction in serotonin transporter (SERT) and dopamine transporter (DAT) function. Persistent...
    143 KB (13,691 words) - 15:20, 3 June 2025
  • Thumbnail for Methamphetamine
    transporters. Other transporters that methamphetamine is known to inhibit are SLC22A3 and SLC22A5. SLC22A3 is an extraneuronal monoamine transporter that...
    170 KB (16,612 words) - 21:29, 29 May 2025
  • Thumbnail for Valbenazine
    Valbenazine (category Monoamine-depleting agents)
    medication used to treat tardive dyskinesia. It acts as a vesicular monoamine transporter 2 (VMAT2) inhibitor. Valbenazine is used to treat tardive dyskinesia...
    12 KB (912 words) - 22:29, 29 May 2025
  • Thumbnail for Dopamine
    dopamine transporter or by the plasma membrane monoamine transporter. Once back in the cytosol, dopamine can either be broken down by a monoamine oxidase...
    140 KB (14,370 words) - 03:43, 11 June 2025
  • influenced by heredity and that a specific gene, called vesicular monoamine transporter 2 (VMAT2), predisposes humans towards spiritual or mystic experiences...
    9 KB (1,046 words) - 17:46, 25 May 2025