A multicenter research trial is a clinical trial that involves more than one independent medical institutions in enrolling and following trial participants...
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Multicenter Automatic Defibrillator Implantation Trial and MADIT II are implantable cardioverter defibrillator (or ICD) trials which investigate whether...
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combined with "stratified randomization", for example by center in a multicenter trial, to "ensure good balance of participant characteristics in each group...
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Polish Adult Leukemia Group (PALG) of a prospective, randomized, multicenter trial". Blood. 109 (9): 3672–5. doi:10.1182/blood-2006-08-042929. PMID 17209059...
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therapy: results of a randomized, double-blind, placebo-controlled, multicenter trial". Arch Dermatol. 140 (12): 1453–9. doi:10.1001/archderm.140.12.1453...
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medications target interleukin-1 (IL-1), particularly IL-1β. A randomized, multicenter trial reported better outcomes in a group of 12 patients treated with anakinra...
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Durvalumab (section Clinical trials)
AEGEAN (NCT03800134), a randomized, double-blind, placebo-controlled multicenter trial in 802 participants with previously untreated and resectable squamous...
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Waninger AL, Iyengar S, et al. (2005). "A double-blind, randomized multicenter trial comparing duloxetine with placebo in the management of diabetic peripheral...
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Phases of clinical research (redirect from Phase I clinical trial)
in clinical practice. Phase III studies are randomized controlled multicenter trials on large patient groups (300–3,000 or more depending upon the disease/medical...
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ablation of painful osseous metastases: a multicenter American College of Radiology Imaging Network trial". Cancer. 116 (4): 989–997. doi:10.1002/cncr...
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1988). "Alprazolam in panic disorder and agoraphobia: results from a multicenter trial. II. Patient acceptance, side effects, and safety". Archives of General...
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2023). A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Trial to Evaluate the Safety and Efficacy of AMX0035 Versus Placebo for...
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ablation for Barrett's esophagus: 5-year outcomes from a prospective multicenter trial". Endoscopy. 42 (10): 781–9. doi:10.1055/s-0030-1255779. PMID 20857372...
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experimental doses of 400 mg have rendered little response. A large, multicenter trial comparing carbamazepine and lithium over two and a half years found...
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Encorafenib (section Clinical trials)
States was based on a randomized, active-controlled, open-label, multicenter trial (COLUMBUS; NCT01909453) in 577 participants with BRAF V600E or V600K...
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versus Sutured Gastrointestinal Anastomoses in the Trauma Patient: A Multicenter Trial". Journal of Trauma-Injury Infection & Critical Care. 51 (6): 1054–1061...
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nirsevimab based on three trials, two of which were randomized, double-blind, placebo-controlled, multicenter clinical trials (Trials 03, 04 and 05). The key...
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Decompressive craniectomy (section DECRA trial)
RESCUE-ASDH study Official RESCUE-ASDH Trial Site is a multicenter, pragmatic, parallel group randomised trial that aims to compare the clinical and cost-effectiveness...
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(Astelin NS) for seasonal allergic rhinitis: a 4-week comparative multicenter trial". Annals of Allergy, Asthma & Immunology. 76 (2): 181–8. doi:10...
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failure in toddlers with Turner syndrome: a randomized, controlled, multicenter trial". The Journal of Clinical Endocrinology and Metabolism. 92 (9): 3406–3416...
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with a combination of amitriptyline and haloperidol--a double-blind multicenter trial". Journal of Psychiatric Research. 43 (7): 702–710. doi:10.1016/j...
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support replication of results. An experimental design or randomized clinical trial requires careful consideration of several factors before actually doing...
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Atezolizumab (section Clinical trials)
based on IMpassion130 (NCT02425891), a multicenter, international, double-blinded, placebo-controlled, randomized trial that included 902 participants with...
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Gilbert EM, Miller RH, Keefe DL, Somberg JC, et al. (October 1986). "Multicenter trial of sotalol for suppression of frequent, complex ventricular arrhythmias:...
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cutaneous T-cell lymphoma: positive results of a randomized, controlled, multicenter trial testing the efficacy and safety of a novel mechlorethamine, 0.02%...
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"Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life". Blood. 105 (6):...
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govitecan-hziy was approved based on the results of IMMU-132-01, a multicenter, single-arm clinical trial (NCT01631552) of 108 participants with metastatic triple-negative...
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therapy in patients with severe alcoholic hepatitis. A randomized multicenter trial". Annals of Internal Medicine. 110 (9): 685–90. doi:10.7326/0003-4819-110-9-685...
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Lisocabtagene maraleucel's safety and efficacy were established in a multicenter clinical trial of more than 250 adults with refractory or relapsed large B-cell...
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prostatic carcinoma: final report of a double-blind, randomized, multicenter trial. Casodex Combination Study Group". Urology. 50 (3): 330–6. doi:10...
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