genetics, the mutation rate is the frequency of new mutations in a single gene, nucleotide sequence, or organism over time. Mutation rates are not constant...

In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain...

threshold (or critical mutation rate) is a limit on the number of base pairs a self-replicating molecule may have before mutation will destroy the information...

of mutational load (total mutations present in a cell) and mutation rate per cell division (new mutations with each mitosis), somatic mutation rates were...

Mutation–selection balance is an equilibrium in the number of deleterious alleles in a population that occurs when the rate at which deleterious alleles...

deleterious mutation rate summed over many independent sites. The intuition for the lack of dependence on the selection coefficient is that while a mutation with...

population size and mutation rate, and fixation probability of a beneficial mutation is inversely related to population size and mutation rate. LaBar and Adami...

thousands of locations within an organism's genome. They have a higher mutation rate than other areas of DNA leading to high genetic diversity. Microsatellites...

genetics, mutations in which natural selection does not affect the spread of the mutation in a species are termed neutral mutations. Neutral mutations that...

Mutation bias refers to a predictable or systematic difference in rates for different types of mutation. The types are most often defined by the molecular...

genetic information in a lineage of organisms due to high mutation rates. The mutation rate above which error catastrophe occurs is called the error threshold...

germline mutation, or germinal mutation, is any detectable variation within germ cells (cells that, when fully developed, become sperm and ova). Mutations in...

A de novo mutation (DNM) is any mutation or alteration in the genome of an individual organism (human, animal, plant, microbe, etc.) that was not inherited...

that mortality exceeds the birth rate. The mechanism behind mutational meltdown is that a spontaneous deleterious mutation is introduced and after some time...

The human mitochondrial molecular clock is the rate at which mutations have been accumulating in the mitochondrial genome of hominids during the course...

most mutations are deleterious, so the optimal mutation rate for a species may be a trade-off between the damage from a high deleterious mutation rate and...

Schürenkamp M, Pfeiffer H, Neuhuber F, Brinkmann B (2015). "Elevated germline mutation rate in teenage fathers". Proc R Soc B. 282 (1803): 1–6. doi:10.1098/rspb...

sites and mutation rate lined up, then Cucurbita pepo would have a lower mutation rate and more RNA editing sites. However the mutation rate is four times...

number of resistant colonies. Assuming a constant rate of mutation, Luria hypothesized that if mutations occurred after and in response to exposure to the...

population mutation rate is mainly determined by the population size. Large populations are predicted to generally have lower mutation rates than smaller...

non-recombining sex chromosomes, due to three common evolutionary forces: high mutation rate, inefficient selection, and genetic drift. With a 30% difference between...

Not surprisingly, the estimated effective mutation rates θ = 4NAμ are comparable for the two mutation rates we considered, and are equal to 1.4 × 10−3/bp/generation...

Mutation frequency and mutation rates are highly correlated to each other. Mutation frequencies test are cost effective in laboratories however; these...

of higher mutation rates to be favored by natural selection on evolvability. A hypothetical mutator M increases the general mutation rate in the area...

In genetics, a nonsense mutation is a point mutation in a sequence of DNA that results in a nonsense codon, or a premature stop codon in the transcribed...

gives RNA primers for DNA synthesis to strands.[citation needed] The mutation rate of phiX174 is estimated to be 1.0 x 10−6 substitutions per base per...

fixation (by drift or selection), with a rate specified by multiplying a rate of introduction (based on the mutation rate) with a probability of fixation (based...

somatic mutations (acquired mutations). It has been demonstrated through research that long lived plants can have higher per generation mutation rate (based...

relationship between the mean optimal age at maturity and mutation rates per gene. Mutation accumulation affects the allocation of energy, and time that...

between somatic mutation rate and lifespan across different mammalian species suggests that evolution may constrain somatic mutation rates, perhaps by selection...