• Nature Methods is a monthly peer-reviewed scientific journal covering new scientific techniques. It was established in 2004 and is published by Springer...
    3 KB (170 words) - 10:47, 18 June 2025
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    journals including Nature Neuroscience, Nature Biotechnology, Nature Methods, the Nature Clinical Practice series of journals, Nature Structural & Molecular...
    50 KB (5,386 words) - 07:33, 19 June 2025
  • Thumbnail for RNA-Seq
    RNA-Seq (section Methods)
    sequencing-based methods. These progressed from Sanger sequencing of Expressed sequence tag libraries, to chemical tag-based methods (e.g., serial analysis...
    87 KB (9,425 words) - 12:36, 10 June 2025
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    method in the last several centuries, nature became the passive reality, organized and moved by divine laws. With the Industrial Revolution, nature increasingly...
    90 KB (9,645 words) - 12:27, 17 June 2025
  • sequencing". Nature Methods. 11 (1): 18. doi:10.1038/nmeth.2771. PMID 24524131. S2CID 5252333. "Method of the year 2013". Nature Methods. 11 (1): 1. January...
    75 KB (8,675 words) - 21:36, 3 June 2025
  • Thumbnail for Cryogenic electron microscopy
    structure determination of biomolecules in solution." Nature Methods also named cryo-EM as the "Method of the Year" in 2015. In the 1960s, the use of transmission...
    39 KB (4,681 words) - 12:45, 23 May 2025
  • Thumbnail for X-Seed 4000
    ultra-modern and technological living and interaction with wildlife and nature. Methods of transportation within the X-seed would most likely include Maglev...
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  • arrays, and later reverse transcriptase quantitative PCR (RT-qPCR) methods, but these methods are laborious and can only capture a tiny subsection of a transcriptome...
    120 KB (12,519 words) - 13:36, 25 January 2025
  • with light". Nature Methods. 8 (1): 24–25. doi:10.1038/nmeth.f.323. S2CID 5808517. Editorial: "Method of the Year 2010". Nature Methods. 8 (1): 1. 2010...
    108 KB (11,930 words) - 09:14, 11 June 2025
  • Thumbnail for Multiomics
    cells in the tissue. The number of Spatial Omics methods published still lags behind the number of methods published for Single-Cell multiomics, but the...
    46 KB (5,003 words) - 13:06, 29 May 2025
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    lineages in larval Drosophila brains. Fiji was prominently featured in Nature Methods review supplement on visualization. Fiji is fully open source. Its sources...
    11 KB (1,025 words) - 08:47, 6 June 2024
  • Thumbnail for Genome editing
    nucleases (TALENs) and engineered meganucleases—were selected by Nature Methods as the 2011 Method of the Year. The CRISPR-Cas system was selected by Science...
    79 KB (9,365 words) - 19:52, 22 May 2025
  • resolvable in time. These methods include super-resolution optical fluctuation imaging (SOFI) and all single-molecule localization methods (SMLM), such as SPDM...
    92 KB (10,673 words) - 20:55, 7 June 2025
  • Visible Embryo Project Spatial biology "Method of the Year 2020: spatially resolved transcriptomics". Nature Methods. 18 (1): 1. January 2021. doi:10...
    64 KB (7,251 words) - 12:38, 23 May 2025
  • Thumbnail for Light sheet fluorescence microscopy
    1155/2012/206238. PMC 3335623. PMID 22567307. Editorial: "Method of the Year 2014". Nature Methods. 12 (1): 1. 30 December 2014. doi:10.1038/nmeth.3251. PMID 25699311...
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  • concentrations. Light field microscopy methods extend functional readout of neural activity capabilities in 3D volumes. Methods such as fiber photometry, miniscopes...
    34 KB (3,795 words) - 22:19, 16 June 2025
  • Thumbnail for Philosophy
    Philosophy (section Methods)
    that promote different principles, theories, or methods. Philosophers use a great variety of methods to arrive at philosophical knowledge. They include...
    196 KB (17,452 words) - 05:56, 19 June 2025
  • to the timely nature of signals, they are usually communicated via email, website, SMS, RSS, tweet or other relatively immediate method. In many jurisdictions...
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  • Thumbnail for Chromosome conformation capture
    or 3C-based methods) are a set of molecular biology methods used to analyze the spatial organization of chromatin in a cell. These methods quantify the...
    49 KB (5,404 words) - 14:29, 23 May 2025
  • 2006). "Channelrhodopsin-2 and optical control of excitable cells". Nature Methods. 3 (10): 785–792. doi:10.1038/nmeth936. PMID 16990810. S2CID 15096826...
    54 KB (5,976 words) - 06:39, 29 April 2025
  • "RNA-guided gene activation by CRISPR-Cas9-based transcription factors". Nature Methods. 10 (10): 973–6. doi:10.1038/nmeth.2600. PMC 3911785. PMID 23892895...
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  • Thumbnail for Protein
    under a light microscope, other methods have to be employed to determine their structure. Common experimental methods include X-ray crystallography and...
    105 KB (10,971 words) - 20:12, 15 June 2025
  • Thumbnail for Metagenomics
    biology". Nature Methods. 5 (1): 16–8. doi:10.1038/nmeth1156. PMID 18165802. S2CID 1465786. "Metagenomics versus Moore's law". Nature Methods. 6 (9): 623...
    89 KB (9,246 words) - 18:49, 28 May 2025
  • Thumbnail for ATAC-seq
    profiling of open chromatin, DNA-binding proteins and nucleosome position". Nature Methods. 10 (12): 1213–8. doi:10.1038/nmeth.2688. PMC 3959825. PMID 24097267...
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  • optical super-resolution microscopy methods, and were featured as Methods of the Year for 2008 by the Nature Methods journal. The development of PALM as...
    27 KB (3,213 words) - 00:39, 31 May 2025
  • numerous computational methods to predict the 3D structures of proteins from their amino acid sequences, accuracy of such methods in best possible scenario...
    65 KB (5,831 words) - 19:56, 19 June 2025
  • correction methods developed for bulk sequencing data were observed to perform poorly. Consequently, researchers developed statistical methods to correct...
    48 KB (5,796 words) - 16:16, 18 April 2025
  • Epigenomics (section Methods)
    "epiGBS: reference-free reduced representation bisulfite sequencing". Nature Methods. 13 (4): 322–324. doi:10.1038/nmeth.3763. PMID 26855363. S2CID 10457615...
    44 KB (5,120 words) - 21:31, 24 May 2025
  • Thumbnail for HTTP 404
    2004 by Ziv Bar-Yossef et al. Soft 404s are problematic for automated methods of discovering whether a link is broken. Some search engines, like Yahoo...
    16 KB (1,945 words) - 23:09, 3 June 2025
  • Thumbnail for Tandem mass spectrometry
    Mass Spectrometry-Based Proteomics: An Overview". Quantitative Methods in Proteomics. Methods in Molecular Biology. Vol. 893. pp. 85–100. doi:10.1007/978-1-61779-885-6_7...
    60 KB (7,443 words) - 00:43, 3 October 2024