• Thumbnail for Nidogen-2
    Nidogen-2, also known as osteonidogen, is a basal lamina protein of the nidogen family. It was the second nidogen to be described after nidogen-1 (entactin)...
    5 KB (602 words) - 06:41, 19 July 2025
  • parahoxozoans. Two nidogens have been identified in humans: nidogen-1 (NID1) and nidogen-2 (NID2). Remarkably, vertebrates are still capable of stabilizing...
    5 KB (584 words) - 14:01, 10 September 2024
  • Thumbnail for Nidogen-1
    Nidogen-1 (NID-1), formerly known as entactin, is a protein that in humans is encoded by the NID1 gene. Both nidogen-1 and nidogen-2 are essential components...
    6 KB (724 words) - 18:05, 16 July 2025
  • Thumbnail for Laminin subunit gamma-1
    PMC 2133008. PMID 9647658. Kohfeldt E, Sasaki T, Göhring W, Timpl R (1998). "Nidogen-2: a new basement membrane protein with diverse binding properties". J....
    9 KB (1,195 words) - 06:18, 19 July 2025
  • SNED1 (Sushi, Nidogen, and EGF-like Domains) is an extracellular matrix (ECM) protein expressed at low levels in a wide range of tissues. The gene encoding...
    20 KB (2,400 words) - 03:09, 30 March 2024
  • Thumbnail for Laminin
    Laminin (redirect from Laminin-2)
    1995). "Low nidogen affinity of laminin-5 can be attributed to two serine residues in EGF-like motif gamma 2III4". FEBS Letters. 365 (2–3): 129–132....
    31 KB (3,372 words) - 16:39, 28 July 2025
  • Thumbnail for Collagen, type XIII, alpha 1
    collagen ectodomain is a 150-nm rod and capable of binding to fibronectin, nidogen-2, perlecan, and heparin". J. Biol. Chem. 277 (25): 23092–9. doi:10.1074/jbc...
    7 KB (893 words) - 16:08, 17 July 2025
  • Thumbnail for Collagen, type XVIII, alpha 1
    (1999). "Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins". FEBS Lett. 460 (2): 280–4. doi:10.1016/S0014-5793(99)01362-9...
    8 KB (1,042 words) - 16:57, 16 July 2025
  • Thumbnail for L-Photo-methionine
    basement membranes of higher organisms. Nidogens help with the formation of the basement. With both laminins and nidogens present, both interact with each other...
    21 KB (2,542 words) - 23:21, 19 June 2025
  • Thumbnail for FBLN2
    (1999). "Tropoelastin binding to fibulins, nidogen-2 and other extracellular matrix proteins". FEBS Lett. 460 (2): 280–4. doi:10.1016/S0014-5793(99)01362-9...
    10 KB (1,268 words) - 08:10, 20 February 2025
  • Thumbnail for Glomerulus (kidney)
    podocytes. It consists mainly of laminins, type IV collagen, agrin, and nidogen, which are synthesized and secreted by both endothelial cells and podocytes...
    17 KB (1,804 words) - 16:30, 28 October 2024
  • Thumbnail for Cornea
    layer composed of collagen (mainly type I collagen fibrils), laminin, nidogen, perlecan and other HSPGs that protects the corneal stroma. When discussed...
    29 KB (3,330 words) - 21:33, 15 July 2025
  • Thumbnail for Extracellular matrix
    cell adhesion. Laminins bind other ECM components such as collagens and nidogens. There are many cell types that contribute to the development of the various...
    37 KB (4,261 words) - 21:43, 17 July 2025
  • Thumbnail for Basement membrane
    membrane Basal lamina Lamina lucida laminin integrins (hemidesmosomes) nidogens dystroglycans Lamina densa collagen IV (coated with perlecan, rich in heparan...
    12 KB (1,239 words) - 11:02, 24 May 2025
  • Thumbnail for Perlecan
    W, Mann K, Timpl R (August 2001). "Mapping of binding sites for nidogens, fibulin-2, fibronectin and heparin to different IG modules of perlecan". J...
    84 KB (11,012 words) - 22:08, 15 July 2025
  • serves as a major component of the endomysium. Collagen constitutes 1% to 2% of muscle tissue and 6% by weight of skeletal muscle. The fibroblast is the...
    68 KB (7,452 words) - 13:33, 23 July 2025
  • Thumbnail for Metastatic breast cancer
    cleaves components of the basal lamina such as collagen type IV, laminin 5, nidogen (entactin) and other ECM proteins such as tenascin, aggrecan and fibronectin...
    42 KB (5,262 words) - 00:36, 30 June 2025
  • Thumbnail for Axonal transport
    neurotoxin is internalised at the neuromuscular junction through binding the nidogen proteins and is retrogradely transported towards the soma in signaling...
    22 KB (2,637 words) - 20:29, 11 July 2025
  • Thumbnail for Diabetic foot ulcer
    and endothelial basement membrane also contains laminin, perlecan, and nidogen. Hyaluronic acid, a pure glycosaminoglycan component, is found in high...
    71 KB (8,396 words) - 03:34, 28 July 2025
  • Thumbnail for FBLN1
    to a number of extracellular matrix constituents including fibronectin, nidogen-1, and the proteoglycan, versican. Fibulin-1 is also a blood protein capable...
    13 KB (1,653 words) - 16:33, 17 July 2025
  • The major components of Cultrex BME include laminin, collagen, entactin/nidogen, and heparin sulfate proteoglycans. These components are found in the basement...
    7 KB (898 words) - 07:04, 10 August 2024
  • type IV collagen suprastructure containing laminins (laminin-5), entactin/nidogen or the perlecan on the extracellular surface of the hemidesmosome, laminin-5...
    11 KB (1,244 words) - 17:04, 17 July 2025
  • Thumbnail for Laminin subunit alpha-1
    Immunol. Ther. Exp. (Warsz.). 45 (2–3): 255–9. PMID 9597096. O'Grady P, Thai TC, Saito H (1998). "The Laminin–Nidogen Complex is a Ligand for a Specific...
    8 KB (1,008 words) - 06:18, 19 July 2025
  • Thumbnail for Collagen, type IV, alpha 1
    102 (2): 139–48. doi:10.1016/0002-9394(86)90134-0. PMID 2426947. Aumailley M, Wiedemann H, Mann K, Timpl R (September 1989). "Binding of nidogen and the...
    18 KB (2,367 words) - 16:57, 16 July 2025
  • Thumbnail for MMP19
    "Activity of MMP-19 inhibits capillary-like formation due to processing of nidogen-1". Cell Mol Life Sci. 61 (14): 1826–33. doi:10.1007/s00018-004-4105-0...
    8 KB (964 words) - 17:58, 16 July 2025
  • Thumbnail for PTPRF
    15611. PMID 9624153. O'Grady P, Thai TC, Saito H (1998). "The Laminin–Nidogen Complex is a Ligand for a Specific Splice Isoform of the Transmembrane...
    12 KB (1,451 words) - 22:13, 15 July 2025
  • Thumbnail for Laminin, beta 1
    -2". Am. J. Physiol. 273 (6 Pt 1): G1341–8. doi:10.1152/ajpgi.1997.273.6.G1341. PMID 9435560. O'Grady P, Thai TC, Saito H (1998). "The laminin-nidogen...
    9 KB (1,257 words) - 06:18, 19 July 2025