• A nuclear localization signal or sequence (NLS) is an amino acid sequence that 'tags' a protein for import into the cell nucleus by nuclear transport...
    15 KB (2,036 words) - 22:45, 26 August 2024
  • Thumbnail for Lamin
    Lamin (redirect from Nuclear lamins)
    the type of lamin. However, all C-terminal domains contain a nuclear localization sequence (NLS). Similar to other IF proteins, lamins self-assemble into...
    18 KB (2,198 words) - 02:12, 10 March 2025
  • nucleus. It does so by binding to specific recognition sequences, called nuclear localization sequences (NLS). Importin has two subunits, importin α and importin...
    18 KB (2,026 words) - 20:24, 2 April 2024
  • referred to as signal sequence, targeting signal, localization signal, localization sequence, transit peptide, leader sequence or leader peptide) is a...
    15 KB (1,777 words) - 04:17, 2 March 2025
  • Thumbnail for Dishevelled
    the cytoplasm and nucleus, via a conserved nuclear export sequence (NES) and a nuclear localization sequence (NLS), both necessary for proper functioning...
    12 KB (1,387 words) - 16:33, 27 February 2025
  • Thumbnail for Major capsid protein VP1
    icosahedral assembly. The C-terminus also contains a basic nuclear localization sequence,: 316  while the N-terminus - which is oriented toward the center...
    11 KB (1,059 words) - 00:01, 3 December 2023
  • Thumbnail for SV40 large T antigen
    protein to study nuclear localization signals (NLSs). It is imported into the nucleus by its interaction with importin α. The NLS sequence is PKKKRKV. SV40...
    12 KB (1,413 words) - 20:11, 3 January 2023
  • Thumbnail for Transportin 1
    This protein is a karyopherin which interacts with nuclear localization sequence to target nuclear proteins to the nucleus. The classical karyopherin...
    12 KB (1,531 words) - 13:22, 23 December 2023
  • through the addition of a nuclear localization sequence (NLS) that promotes passage through the nuclear envelope via nuclear pores. While some proteins...
    53 KB (6,405 words) - 19:15, 19 March 2025
  • Thumbnail for Cell biology
    releasing the catalytic subunit. The catalytic subunit has a nuclear localization sequence which prompts it to go into the nucleus and phosphorylate other...
    42 KB (5,255 words) - 02:53, 2 May 2025
  • Look up localization, L10n, or localize in Wiktionary, the free dictionary. Localization or localisation may refer to: Localization of function, locating...
    4 KB (506 words) - 17:52, 1 May 2025
  • Thumbnail for NeuN
    adds a C-terminal PY type nuclear localization sequence, which presumably explains why NeuN/Fox-3 protein can be both nuclear and, in some cell types,...
    8 KB (982 words) - 19:03, 25 June 2024
  • Thumbnail for MSH2
    N-terminal disordered domain. Conversely, MSH2 does not have a nuclear localization sequence (NLS), so it is believed that MSH2 and MSH6 dimerize in the...
    35 KB (4,237 words) - 07:05, 26 August 2024
  • Thumbnail for Importin subunit alpha-1
    "Identification of hSRP1 alpha as a functional receptor for nuclear localization sequences". Science. 268 (5213): 1049–53. Bibcode:1995Sci...268.1049W...
    13 KB (1,632 words) - 12:07, 22 December 2023
  • dominant role in recognition of the DR sequences in the transposon. The RED subdomain overlaps with the nuclear localization signal, but its function remains...
    30 KB (2,762 words) - 12:46, 17 November 2024
  • Thumbnail for G2 phase
    accomplished via removal of nuclear localization sequence (NLS)-obscuring phosphates and phosphorylation of the nuclear export signal. It is thought...
    22 KB (2,818 words) - 07:39, 3 June 2024
  • Thumbnail for T-cell receptor
    state, NFAT cannot enter the nucleus as its nuclear localization sequence (NLS) cannot be recognized by nuclear transporters due to phosphorylation by GSK-3...
    44 KB (5,378 words) - 07:54, 5 May 2025
  • Thumbnail for Archaea
    known life forms List of Archaea genera List of sequenced archaeal genomes Nuclear localization sequence Stirrup protein domain The Surprising Archaea (book)...
    153 KB (16,713 words) - 12:00, 5 May 2025
  • Thumbnail for Heterogeneous ribonucleoprotein particle
    mRNA in the cytoplasm. However, hnRNPs also have their own nuclear localization sequences (NLS) and are therefore found mainly in the nucleus. Though...
    16 KB (1,987 words) - 08:35, 13 March 2025
  • Thumbnail for Cyclin E/Cdk2
    typically appears as a nuclear protein in images as its nuclear import is more rapid than its export. Cyclin E's nuclear localization sequence (NLS) allows the...
    11 KB (1,404 words) - 07:30, 19 November 2024
  • Thumbnail for ZFX
    contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type...
    6 KB (721 words) - 03:48, 9 September 2024
  • Thumbnail for Rel homology domain
    family. The dimerization subdomain is immediately followed by a nuclear localization sequence that also comprises the site for inhibitory interactions with...
    3 KB (307 words) - 19:27, 12 May 2024
  • Thumbnail for PAX5
    "BSAP (Pax5)-importin alpha 1 (Rch1) interaction identifies a nuclear localization sequence". The Journal of Biological Chemistry. 275 (22): 16752–7. doi:10...
    11 KB (1,433 words) - 06:21, 3 June 2024
  • Thumbnail for Nuclear pore complex
    of which nuclear localization signal (NLS) are best characterized. Several NLS sequences are known, generally containing a conserved sequence with basic...
    29 KB (3,346 words) - 19:09, 17 December 2024
  • Thumbnail for SCF complex
    stable throughout the cell cycle and is localized to the nucleus due to the presence of a nuclear localization sequence (NLS). SCF-Fbw7 targets Sic1—when at...
    16 KB (2,021 words) - 15:42, 12 April 2025
  • Thumbnail for Fibroblast growth factor 1
    FGF1 can also function intracellularly. The protein has a nuclear localization sequence (NLS) but the route that FGF1 takes to get to the nucleus is...
    20 KB (2,311 words) - 22:01, 16 July 2024
  • nucleus from the cytoplasm carry nuclear localization signals (NLS) that are bound by importins. An NLS is a sequence of amino acids that acts as a tag...
    8 KB (976 words) - 22:34, 1 July 2024
  • Thumbnail for Nucleoplasm
    Nucleoplasm (redirect from Nuclear sap)
    a third of these have been found to localize to the nucleoplasm via targeting by a nuclear localization sequence (NLS). Cytosolic proteins, known as importins...
    17 KB (1,949 words) - 13:24, 8 January 2025
  • Thumbnail for Mef2
    heterodimerize, and a classic nuclear localization sequence (NLS) in the C-terminus of Mef2A, -C, and – D ensures nuclear localization of the protein. D-Mef2...
    15 KB (1,906 words) - 00:35, 31 March 2025
  • Thumbnail for Nuclear medicine
    (1985). "Localization of cortical areas activated by thinking". Journal of Neurophysiology. Vol. 53, no. 5. pp. 1219–1243. "What is nuclear medicine"...
    39 KB (4,404 words) - 17:41, 1 May 2025