E3 SUMO-protein ligase PIAS1 is an enzyme that in humans is encoded by the PIAS1 gene. This gene encodes a member of the mammalian PIAS [protein inhibitor...
11 KB (1,351 words) - 02:04, 4 March 2023
mammalian PIAS family are encoded by four genes: PIAS1, PIAS2 (PIASx), PIAS3, and PIAS4 (PIASy). Apart from PIAS1, each gene encodes two protein isoforms. Homologues...
29 KB (3,175 words) - 21:59, 29 May 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
15 KB (1,777 words) - 07:49, 20 May 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
29 KB (3,502 words) - 12:50, 3 March 2025
Mdm2, MDM4, MED1, MAPK9, MNAT1, NDN, NCL, NUMB, NF-κB, P16, PARC, PARP1, PIAS1, CDC14B, PIN1, PLAGL1, PLK3, PRKRA, PHB, PML, PSME3, PTEN, PTK2, PTTG1,...
131 KB (14,418 words) - 16:00, 7 June 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
33 KB (3,238 words) - 16:28, 25 May 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
53 KB (6,405 words) - 14:47, 8 June 2025
O43692 12110 PI16 HGNC:21245 Q6UXB8 12111 PIANP HGNC:25338 Q8IYJ0 12112 PIAS1 HGNC:2752 O75925 12113 PIAS2 HGNC:17311 O75928 12114 PIAS3 HGNC:16861 Q9Y6X2...
282 KB (17 words) - 09:28, 10 February 2025
JAK-STAT signaling dynamics. PIAS are a four-member protein family made of: PIAS1, PIAS3, PIASx, and PIASγ. The proteins add a marker, called SUMO (small...
62 KB (6,845 words) - 06:02, 23 May 2025
transcription factor has been shown to interact with Histone deacetylase 2, PIAS1, E2F1 and GABPA. GRCh38: Ensembl release 89: ENSG00000172845 – Ensembl,...
4 KB (517 words) - 16:48, 9 April 2024
signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction". Proceedings of the National Academy of...
31 KB (3,768 words) - 02:37, 2 June 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
49 KB (5,534 words) - 15:15, 2 May 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
9 KB (901 words) - 02:56, 23 May 2024
HERC2, HERC3, HERC4, HERC5, HERC6 HUWE1, ITCH NEDD4, NEDD4L PPIL2 PRPF19 PIAS1, PIAS2, PIAS3, PIAS4 RANBP2 RNF4, RNF167 RBX1 SMURF1, SMURF2 STUB1 TOPORS...
40 KB (4,436 words) - 07:10, 2 June 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
11 KB (1,152 words) - 17:58, 25 May 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
76 KB (8,708 words) - 09:25, 13 March 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
51 KB (5,551 words) - 22:14, 23 April 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
40 KB (4,909 words) - 18:03, 25 May 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
10 KB (1,274 words) - 23:14, 6 February 2024
(2005). "Sumoylation of the net inhibitory domain (NID) is stimulated by PIAS1 and has a negative effect on the transcriptional activity of Net". Oncogene...
7 KB (899 words) - 12:16, 1 August 2023
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
5 KB (650 words) - 14:32, 17 February 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
22 KB (2,320 words) - 09:55, 22 May 2025
Namikoshi K, et al. (2004). "DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation". Mol. Cell. Biol. 24 (24): 10733–41. doi:10...
6 KB (757 words) - 11:08, 17 October 2022
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
101 KB (11,338 words) - 19:50, 22 April 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
8 KB (787 words) - 16:36, 28 October 2022
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
34 KB (4,108 words) - 02:42, 22 November 2024
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
51 KB (5,785 words) - 23:20, 15 May 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
2 KB (215 words) - 03:26, 28 March 2024
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
31 KB (3,599 words) - 03:24, 2 June 2025
SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
5 KB (558 words) - 17:39, 7 June 2022