• Thumbnail for PIAS1
    E3 SUMO-protein ligase PIAS1 is an enzyme that in humans is encoded by the PIAS1 gene. This gene encodes a member of the mammalian PIAS [protein inhibitor...
    11 KB (1,351 words) - 02:04, 4 March 2023
  • Thumbnail for Protein inhibitor of activated STAT
    mammalian PIAS family are encoded by four genes: PIAS1, PIAS2 (PIASx), PIAS3, and PIAS4 (PIASy). Apart from PIAS1, each gene encodes two protein isoforms. Homologues...
    29 KB (3,179 words) - 10:37, 24 June 2025
  • SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    15 KB (1,777 words) - 07:49, 20 May 2025
  • Thumbnail for Chaperone (protein)
    SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    29 KB (3,502 words) - 12:50, 3 March 2025
  • O43692 12110 PI16 HGNC:21245 Q6UXB8 12111 PIANP HGNC:25338 Q8IYJ0 12112 PIAS1 HGNC:2752 O75925 12113 PIAS2 HGNC:17311 O75928 12114 PIAS3 HGNC:16861 Q9Y6X2...
    282 KB (17 words) - 09:28, 10 February 2025
  • Thumbnail for P53
    Mdm2, MDM4, MED1, MAPK9, MNAT1, NDN, NCL, NUMB, NF-κB, P16, PARC, PARP1, PIAS1, CDC14B, PIN1, PLAGL1, PLK3, PRKRA, PHB, PML, PSME3, PTEN, PTK2, PTTG1,...
    131 KB (14,423 words) - 10:16, 24 June 2025
  • Thumbnail for Post-translational modification
    SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    33 KB (3,238 words) - 16:28, 25 May 2025
  • Thumbnail for Protein folding
    SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    76 KB (8,712 words) - 06:16, 25 June 2025
  • Thumbnail for STAT1
    signal transducer and activator of transcription (STAT) 1 (PIAS1) in cytokine-induced PIAS1-Stat1 interaction". Proceedings of the National Academy of...
    31 KB (3,768 words) - 02:37, 2 June 2025
  • Thumbnail for Ubiquitin ligase
    HERC2, HERC3, HERC4, HERC5, HERC6 HUWE1, ITCH NEDD4, NEDD4L PPIL2 PRPF19 PIAS1, PIAS2, PIAS3, PIAS4 RANBP2 RNF4, RNF167 RBX1 SMURF1, SMURF2 STUB1 TOPORS...
    40 KB (4,436 words) - 16:32, 23 June 2025
  • SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    49 KB (5,534 words) - 19:53, 19 June 2025
  • Thumbnail for Ubiquitin-protein ligase E3B
    SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    9 KB (901 words) - 02:56, 23 May 2024
  • SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    53 KB (6,405 words) - 19:55, 19 June 2025
  • 5444 Zhongshu Tang, Oussama El Far, Heinrich Betz, and Astrid Scheschonka. Pias1 Interaction and Sumoylation of Metabotropic Glutamate Receptor 8. J. Biol...
    7 KB (850 words) - 22:23, 6 May 2025
  • JAK-STAT signaling dynamics. PIAS are a four-member protein family made of: PIAS1, PIAS3, PIASx, and PIASγ. The proteins add a marker, called SUMO (small...
    62 KB (6,845 words) - 06:02, 23 May 2025
  • Thumbnail for Sp3 transcription factor
    transcription factor has been shown to interact with Histone deacetylase 2, PIAS1, E2F1 and GABPA. GRCh38: Ensembl release 89: ENSG00000172845 – Ensembl,...
    4 KB (517 words) - 16:48, 9 April 2024
  • Thumbnail for SMN1
    SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    10 KB (1,274 words) - 23:14, 6 February 2024
  • Thumbnail for ELK3
    (2005). "Sumoylation of the net inhibitory domain (NID) is stimulated by PIAS1 and has a negative effect on the transcriptional activity of Net". Oncogene...
    7 KB (899 words) - 12:16, 1 August 2023
  • Thumbnail for Ubiquitin
    SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    101 KB (11,338 words) - 22:52, 24 June 2025
  • Thumbnail for Chaperonin
    SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    22 KB (2,327 words) - 06:13, 25 June 2025
  • SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    5 KB (650 words) - 09:51, 24 June 2025
  • Thumbnail for SUMO protein
    SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    40 KB (4,909 words) - 18:03, 25 May 2025
  • Thumbnail for TRAP1
    SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    8 KB (787 words) - 16:36, 28 October 2022
  • Thumbnail for Survival of motor neuron
    SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    13 KB (1,384 words) - 23:04, 9 June 2024
  • SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    2 KB (215 words) - 03:26, 28 March 2024
  • Thumbnail for Hsp70
    SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    51 KB (5,785 words) - 23:20, 15 May 2025
  • SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    11 KB (1,152 words) - 17:58, 25 May 2025
  • Thumbnail for Hsp90
    SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    51 KB (5,551 words) - 00:49, 20 June 2025
  • Thumbnail for UBE2I
    DACH1, DNMT3A, DNMT3B, DAXX, ETS1, FHIT, IPO13, MAP3K1 and MITF, P53, PIAS1, PIAS2, RAD51, RANBP2, RANGAP1, SAE2, SALL1, SUMO1, TCF3, TNFRSF1A, TOP1...
    24 KB (2,840 words) - 09:41, 17 February 2023
  • Thumbnail for Von Hippel–Lindau tumor suppressor
    SUMO-activating enzyme SAE1 SAE2 E2 SUMO-conjugating enzyme UBC9 E3 SUMO ligase PIAS1 PIAS2 PIAS3 PIAS4 Other ISG15 URM1 UFM1 NEDD8 (neddylation) FAT10 ATG8 ATG12...
    31 KB (3,599 words) - 03:24, 2 June 2025