I-alpha regulatory subunit is an enzyme that in humans is encoded by the PRKAR1A gene. cAMP is a signaling molecule important for a variety of cellular...
15 KB (1,842 words) - 03:29, 25 December 2023
different. Carney complex is most commonly caused by mutations in the PRKAR1A gene on chromosome 17 (17q23-q24) which may function as a tumor-suppressor...
9 KB (869 words) - 19:57, 27 October 2023
catalytic subunit – PRKACA, PRKACB, PRKACG regulatory subunit type I - PRKAR1A, PRKAR1B regulatory subunit type II - PRKAR2A, PRKAR2B PKA is also commonly...
27 KB (2,665 words) - 17:03, 6 April 2024
needed] Sahut-Barnola et al. used a mouse model to cre-lox knockout the Prkar1a gene specifically from cells of the adrenal cortex and observed that the...
14 KB (1,578 words) - 02:47, 3 December 2023
of transcription 5b (STAT5B), protein kinase A regulatory subunit 1α (PRKAR1A), factor interacting with PAPOLA and CPSF1 (FIP1L1), BCL-6 corepressor...
29 KB (3,150 words) - 09:24, 26 February 2024
have been shown to be recurrently mutated, including TP53, CTNNB1, MEN1, PRKAR1A, RPL22, and DAXX. The telomerase gene TERT is often amplified while ZNRF3...
23 KB (2,065 words) - 13:21, 9 March 2024
aortic valve Acrodysostosis is believed to be caused by mutations in the PRKAR1A gene (type 1) or the PDE4D gene (type 2). It has been suggested that the...
7 KB (588 words) - 21:30, 25 February 2024
P54619 12814 PRKAG2 HGNC:9386 Q9UGJ0 12815 PRKAG3 HGNC:9387 Q9UGI9 12816 PRKAR1A HGNC:9388 P10644 12817 PRKAR1B HGNC:9390 P31321 12818 PRKAR2A HGNC:9391...
282 KB (17 words) - 09:00, 31 May 2024
KCNH1; KCNH2; KCNH3; KCNH4; KCNH5; KCNH6; KCNH7; KCNH8; PNPLA6; PNPLA7; PRKAR1A; PRKAR1B; PRKAR2A; PRKAR2B; PRKG1; PRKG2; RAPGEF2; RAPGEF3; RAPGEF4; RAPGEF6;...
4 KB (327 words) - 22:46, 2 May 2024
protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), mRNA PRKAR1A NM_002734 Regulatory subunit of the cAMP-dependent protein kinases involved...
48 KB (4,612 words) - 23:41, 12 December 2023
benzodiazepine receptor and PKA regulatory subunit type 1A (PRKAR1A)-associated protein PAP7, and studies in PRKAR1A mutant cells and tissues". FASEB J. 17 (9): 1189–91...
4 KB (532 words) - 11:11, 24 January 2024
Adrenocortical Carcinoma 91 Overexpression of IGF2, mutations in TP53, PRKAR1A and other genes, and copy number alterations were common hallmarks; hypoploidy...
82 KB (7,468 words) - 19:06, 19 April 2024
Mitogen-activated protein kinase 9, NCKIPSD, NEU3, PDGFRB, PIK3R1, PLCG1, PRKAR1A, PTK2, PTPN11, PTPN12, PTPN1, PTPN6, PTPRA, RAPGEF1, RET proto-oncogene...
82 KB (9,365 words) - 15:39, 31 March 2024
the team identified a previously unrecognized 2 kilobase deletion in PRKAR1A, the gene responsible for Carney complex. In 2018, as the first co-chair...
22 KB (2,365 words) - 11:34, 3 December 2023
neurodegenerative disorder. PRKAR1B has been shown to interact with AKAP1 and PRKAR1A. GRCh38: Ensembl release 89: ENSG00000188191 – Ensembl, May 2017 GRCm38:...
10 KB (1,198 words) - 06:45, 27 May 2024
inhibition. ARFGEF1 has been shown to interact with FKBP2, ARFGEF2 and PRKAR1A. GRCh38: Ensembl release 89: ENSG00000066777 – Ensembl, May 2017 GRCm38:...
10 KB (1,092 words) - 15:35, 25 January 2024
Protein Description HTT Huntingtin protein APOE Apolipoprotein E PRKAR1A cAMP-dependent protein kinase type I-alpha regulatory subunit FH Fumarate hydratase...
20 KB (1,337 words) - 01:31, 4 November 2023
multiple myeloma (MM) AKAP4 has been shown to interact with: AKAP3, and PRKAR1A. GRCh38: Ensembl release 89: ENSG00000147081 – Ensembl, May 2017 GRCm38:...
11 KB (1,447 words) - 08:18, 7 January 2024
brefeldin A inhibition. ARFGEF2 has been shown to interact with ARFGEF1, PRKAR1A and PRKAR2A. GRCh38: Ensembl release 89: ENSG00000124198 – Ensembl, May...
9 KB (1,103 words) - 21:14, 1 September 2023
signal transduction. AKAP10 has been shown to interact with PDZK1 and PRKAR1A. GRCm38: Ensembl release 89: ENSMUSG00000047804 – Ensembl, May 2017 "Human...
7 KB (967 words) - 12:53, 24 January 2024
cellular compartment. AKAP1 has been shown to interact with: C3orf15, MYCBP, PRKAR1A, PRKAR1B, and PRKAR2A. GRCh38: Ensembl release 89: ENSG00000121057 – Ensembl...
10 KB (1,230 words) - 02:39, 29 November 2023
proteins, such as Cdc53/culin. UBE2M has been shown to interact with NEDD8, PRKAR1A and UBA3. GRCh38: Ensembl release 89: ENSG00000130725 – Ensembl, May 2017...
7 KB (788 words) - 01:42, 17 April 2022
MYLK2 Carney complex variant; 608837; MYH8 Carney complex, type 1; 160980; PRKAR1A Carnitine deficiency, systemic primary; 212140; SLC22A5 Carotid intimal...
234 KB (18,877 words) - 15:43, 9 May 2024