• In neurology, a paroxysmal depolarizing shift (PDS) or depolarizing shift is a hallmark of cellular manifestation of epilepsy. Little is known about the...
    7 KB (855 words) - 23:09, 24 May 2025
  • Thumbnail for Epilepsy
    ictogenesis is often marked by a paroxysmal depolarizing shift, a characteristic pattern of sustained neuronal depolarization followed by rapid repetitive...
    158 KB (17,621 words) - 23:06, 17 June 2025
  • Thumbnail for Spike-and-wave
    complex corresponds to the depolarization of the neuronal membrane potential, also called a paroxysmal depolarizing shift (PDS). The initial understanding...
    29 KB (3,698 words) - 04:18, 9 June 2025
  • Studios, a game developer subsidiary of Paradox Interactive Paroxysmal depolarizing shift, a pre-seizure interictal neuronal EEG spike in epilepsy. Pigment...
    3 KB (383 words) - 17:09, 5 June 2025
  • Thumbnail for Glutamate (neurotransmitter)
    apart, and this firing pattern is similar to what is known as paroxysmal depolarizing shift in epileptic attacks. This change in the resting membrane potential...
    20 KB (2,185 words) - 08:27, 3 April 2025
  • Thumbnail for Eric Kandel
    spike (the intracellular paroxysmal depolarizing shift) and the epileptic runs of spikes (the intracellular sustained depolarization). But, with respect to...
    41 KB (4,490 words) - 04:26, 23 June 2025
  • Paroxysmal extreme pain disorder originally named familial rectal pain syndrome, is a rare disorder whose most notable features are pain in the mandibular...
    12 KB (1,379 words) - 20:48, 28 November 2024
  • Thumbnail for Atrial fibrillation
    category changes to paroxysmal AF. Although people in this category have episodes lasting up to seven days, in most cases of paroxysmal AF, the episodes...
    133 KB (14,858 words) - 18:18, 11 June 2025
  • networks share a common mechanism of formation. In the 1990s, paroxysmal depolarizing shift-type interictal epileptiform discharges has been suggested to...
    18 KB (2,134 words) - 10:34, 2 April 2025
  • Thumbnail for Antiarrhythmic agent
    Elsevier Health Sciences. p. 144. ISBN 9780702055034. "treatment of paroxysmal atrial fibrillation – General Practice Notebook". www.gpnotebook.co.uk...
    21 KB (1,997 words) - 16:47, 25 March 2025
  • recordings show that the peak membrane potential deflection during a paroxysmal depolarizing shift (PDS) is 10mV greater in the apical trunk (supragranular location)...
    45 KB (5,967 words) - 13:52, 12 January 2025
  • Thumbnail for Sodium voltage-gated channel alpha subunit 9
    which has a more depolarized activation threshold that produces most of the transmembrane current responsible for the depolarizing phase of action potentials...
    28 KB (3,238 words) - 15:56, 31 October 2024
  • from the procedure, but therapy can help overcome the symptoms. Benign paroxysmal positional vertigo, or BPPV, is a disorder caused by the breaking off...
    22 KB (2,841 words) - 08:24, 29 April 2025
  • Thumbnail for Wandering atrial pacemaker
    spontaneously depolarizing, each foci acting as a pacemaker for the heart. However, the atrial muscle tissue isn't able to spontaneously depolarize. Therefore...
    7 KB (843 words) - 09:31, 27 September 2023
  • Thumbnail for Bundle branch block
    myocytes, allowing for rapid, coordinated, and synchronous physiologic depolarization of the ventricles.[citation needed] When a bundle branch or fascicle...
    8 KB (840 words) - 20:45, 11 June 2025
  • Thumbnail for Left axis deviation
    congenital heart disease, high potassium levels, emphysema, mechanical shift, and paced rhythm. Symptoms and treatment of left axis deviation depend...
    8 KB (898 words) - 15:42, 13 May 2024
  • Thumbnail for Heart failure
    conducting fiber bundles that originate at the base of the heart and carry depolarizing impulses to the left ventricle). Using a special pacing algorithm, biventricular...
    144 KB (15,674 words) - 03:06, 15 June 2025
  • Thumbnail for Myocardial infarction
    potentially fatal arrhythmia and deliver an electrical shock to the person to depolarize a critical mass of the heart muscle. Taking aspirin helps to reduce the...
    129 KB (13,826 words) - 16:29, 22 May 2025
  • Thumbnail for Cardiac arrest
    electrical current that results in the entire myocardium simultaneously depolarized thereby stopping the arrhythmia. Defibrillators can deliver energy as...
    124 KB (13,684 words) - 21:29, 18 June 2025
  • Thumbnail for Otolithic membrane
    physiology and the characteristics of proven otolithic syndromes. Benign paroxysmal positional vertigo (BPPV) is the most common vestibular system disorder...
    21 KB (2,636 words) - 22:34, 19 April 2025
  • Thumbnail for Right axis deviation
    electrical axis of the heart is the net direction in which the wave of depolarization travels. It is measured using an electrocardiogram (ECG). Normally,...
    15 KB (1,661 words) - 19:51, 6 November 2024
  • Thumbnail for BK channel
    lead to dependency of alcohol initiation of dyskinesias, epilepsy, or paroxysmal movement disorders. Not only are BK channels important in many cellular...
    33 KB (3,794 words) - 21:58, 15 June 2025
  • found a small, hyperpolarizing shift in the midpoint for activation, a result common among FHM1 mutants. This shift results in channels that open at...
    41 KB (4,227 words) - 06:15, 2 June 2025