• Thumbnail for Patch clamp
    The patch clamp technique is a laboratory technique in electrophysiology used to study ionic currents in individual isolated living cells, tissue sections...
    30 KB (3,853 words) - 01:56, 5 June 2024
  • Thumbnail for Electrophysiology
    involves impaling a cell with a fine electrode; patch-clamp recording takes a different approach. A patch-clamp microelectrode is a micropipette with a relatively...
    39 KB (4,537 words) - 20:45, 14 May 2025
  • Thumbnail for Voltage clamp
    fluid while clamping, which is possible using patch clamp techniques. Another disadvantage involves "space clamp" issues. Cole's voltage clamp used a long...
    26 KB (3,681 words) - 22:29, 24 November 2024
  • Patch-sequencing (patch-seq) is a modification of patch-clamp technique that combines electrophysiological, transcriptomic and morphological characterization...
    43 KB (5,261 words) - 15:33, 10 January 2025
  • measurement of current flow across a very small patch of membrane. Voltage clamp is a variation of patch clamp recording in which the membrane is held at a...
    11 KB (1,315 words) - 11:58, 27 February 2025
  • Automated patch clamping is beginning to replace manual patch clamping as a method to measure the electrical activity of individual cells. Different techniques...
    19 KB (2,412 words) - 03:08, 13 April 2024
  • Thumbnail for Ion transporter
    transport chain is regulated by the presence of H+ ions (pH) in solution. A patch clamp is an electrophysiology technique used to study channels and transporters...
    17 KB (2,039 words) - 10:46, 15 November 2024
  • Thumbnail for Dendritic spike
    tool for studying dendritic spikes due to its high level of precision. Patch clamp recording is used to measure electrical activity in neurons. The technique...
    22 KB (2,983 words) - 19:27, 3 April 2025
  • study the function of bacterial ion channels through a technique called patch clamp, which was originally designed for characterizing the behavior of neurons...
    13 KB (1,333 words) - 11:00, 20 January 2025
  • Thumbnail for Erwin Neher
    for liquid junction potentials in patch clamp experiments". Correction for liquid junction potentials in patch clamp experiments. Methods in Enzymology...
    10 KB (811 words) - 04:34, 22 November 2024
  • Thumbnail for Single-molecule experiment
    molecules have been developed. The first single-molecule experiments were patch clamp experiments performed in the 1970s, but these were limited to studying...
    18 KB (2,203 words) - 04:23, 12 February 2024
  • Thumbnail for Action potential
    patch clamp by Erwin Neher and Bert Sakmann. For this discovery, they were awarded the Nobel Prize in Physiology or Medicine in 1991. Patch-clamping verified...
    149 KB (16,451 words) - 05:32, 8 May 2025
  • Look up clamp or clamps in Wiktionary, the free dictionary. Clamp may refer to: Brick clamp, an early method of baking bricks Clamp (tool), a device or...
    2 KB (312 words) - 01:02, 17 May 2025
  • Thumbnail for Ion channel
    electrophysiology, and pharmacology, while using techniques including voltage clamp, patch clamp, immunohistochemistry, X-ray crystallography, fluoroscopy, and RT-PCR...
    51 KB (5,954 words) - 02:21, 2 May 2025
  • proportional to magnitude of the disturbance in the electric field. Patch-Clamp Electrophysiology was developed by Neher and Sakmann in 1976. This technique...
    10 KB (1,321 words) - 13:48, 20 October 2024
  • Thumbnail for Inchworm motor
    connecting the motor to a feedback system. The inchworm motor can be used in patch clamping of biological cells. This technique is most often performed with an...
    4 KB (502 words) - 16:21, 6 January 2025
  • Thumbnail for Hyperpolarization (biology)
    membrane potential. Neuroscientists measure it using a technique known as patch clamping that allows them to record ion currents passing through individual channels...
    11 KB (1,215 words) - 05:13, 7 December 2024
  • Retrieved 2022-03-03. Molleman, Areles (2003). "Patch Clamping: An Introductory Guide to Patch Clamp Electrophysiology". Wiley & Sons. ISBN 978-0-471-48685-5...
    18 KB (1,747 words) - 01:04, 2 March 2025
  • Thumbnail for Bert Sakmann
    function of single ion channels in cells," and the invention of the patch clamp. Bert Sakmann was Professor at Heidelberg University and is an Emeritus...
    8 KB (642 words) - 14:47, 10 January 2025
  • neurons. Several techniques such as intracellular recording, patch-clamp, and voltage-clamp technique, pharmacology, confocal imaging, molecular biology...
    12 KB (1,398 words) - 05:16, 30 July 2024
  • simultaneously from both sides of the die was produced by Yale e-Lab) patch-clamp amplifiers energy harvesting devices three-dimensional (3D) integration...
    11 KB (1,165 words) - 18:03, 13 September 2024
  • relationship Hill equation (biochemistry) Schild plot Del Castillo Katz model Cheng-Prussoff Equation Methods (Organ bath, Ligand binding assay, Patch clamp)...
    11 KB (1,288 words) - 14:01, 6 May 2025
  • single cells due to their low spatial resolution compared to patch clamp and dynamic clamp systems. The complexity of signals an MEA electrode could effectively...
    43 KB (5,095 words) - 14:51, 7 May 2025
  • experiments can be performed on these single isolated cells including patch clamp electrophysiology, calcium fluorescence imaging, and immunocytochemistry...
    13 KB (1,564 words) - 23:27, 2 September 2023
  • ethanol. Voltage clamp recordings have been done on the aplysia neuron. VGCCs were isolated and calcium current was recorded using patch clamp technique having...
    31 KB (3,456 words) - 15:10, 11 May 2025
  • Thumbnail for Pharmacology of ethanol
    ethanol. Voltage clamp recordings have been done on the aplysia neuron. VGCCs were isolated and calcium current was recorded using patch clamp technique having...
    98 KB (10,607 words) - 10:24, 29 April 2025
  • Thumbnail for Classical pharmacology
    relationship Hill equation (biochemistry) Schild plot Del Castillo Katz model Cheng-Prussoff Equation Methods (Organ bath, Ligand binding assay, Patch clamp)...
    5 KB (512 words) - 16:28, 1 February 2025
  • Thumbnail for Orphenadrine
    uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist: binding and patch clamp studies". Journal of Neural Transmission. General Section. 102 (3): 237–46...
    18 KB (1,552 words) - 01:29, 15 January 2025
  • Thumbnail for IC50
    relationship Hill equation (biochemistry) Schild plot Del Castillo Katz model Cheng-Prussoff Equation Methods (Organ bath, Ligand binding assay, Patch clamp)...
    10 KB (1,085 words) - 17:53, 26 February 2025
  • essential to creation of the glass pipettes used for the patch clamp technique of voltage clamping. Various machines and torches/gas burners are used in...
    2 KB (275 words) - 07:57, 22 June 2023